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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal growth factor-activated receptor activity
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Accession:GO:0007175 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.
Synonyms:exact_synonym: EGF receptor downregulation;   down regulation of epidermal growth factor receptor activity;   downregulation of epidermal growth factor receptor activity;   negative regulation of EGF receptor activity;   negative regulation of EGFR activity;   negative regulation of epidermal growth factor receptor activity
 narrow_synonym: inhibition of epidermal growth factor receptor activity
 alt_id: GO:0007177


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negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Casitas B-lineage lymphoma JBrowse link 9 44,142,976 44,234,259 RGD:2290270
G Cblb Casitas B-lineage lymphoma b JBrowse link 16 52,031,230 52,208,047 RGD:2290270
G Cblc Casitas B-lineage lymphoma c JBrowse link 7 19,779,718 19,796,809 RGD:2290270
G Chmp6 charged multivesicular body protein 6 JBrowse link 11 119,913,409 119,919,552 RGD:2290270
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 4 150,853,796 150,868,889 RGD:2290270
G Gprc5a G protein-coupled receptor, family C, group 5, member A JBrowse link 6 135,065,662 135,084,709 RGD:2290270
G Psen1 presenilin 1 JBrowse link 12 83,688,152 83,735,095 RGD:2290270
G Psen2 presenilin 2 JBrowse link 1 180,227,004 180,263,467 RGD:2290270
G Socs4 suppressor of cytokine signaling 4 JBrowse link 14 47,277,143 47,291,591 RGD:2290270
G Socs5 suppressor of cytokine signaling 5 JBrowse link 17 87,107,278 87,137,647 RGD:2290270
G Tsg101 tumor susceptibility gene 101 JBrowse link 7 46,888,949 46,926,320 RGD:2290270
G Vps25 vacuolar protein sorting 25 JBrowse link 11 101,252,326 101,259,551 RGD:2290270
G Zfyve28 zinc finger, FYVE domain containing 28 JBrowse link 5 34,194,893 34,288,368 RGD:2290270
G Zgpat zinc finger, CCCH-type with G patch domain JBrowse link 2 181,364,931 181,380,793 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23017
    biological regulation 12187
      regulation of molecular function 2506
        regulation of signaling receptor activity 128
          regulation of epidermal growth factor-activated receptor activity 26
            negative regulation of epidermal growth factor-activated receptor activity 14
Path 2
Term Annotations click to browse term
  biological_process 23017
    metabolic process 10332
      organic substance metabolic process 9795
        macromolecule metabolic process 8329
          protein metabolic process 5165
            protein modification process 3440
              cellular protein modification process 3440
                peptidyl-amino acid modification 1144
                  peptidyl-tyrosine modification 324
                    peptidyl-tyrosine phosphorylation 321
                      regulation of peptidyl-tyrosine phosphorylation 265
                        regulation of protein tyrosine kinase activity 76
                          regulation of epidermal growth factor-activated receptor activity 26
                            negative regulation of epidermal growth factor-activated receptor activity 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.