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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal growth factor-activated receptor activity
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Accession:GO:0007175 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.
Synonyms:exact_synonym: EGF receptor downregulation;   down regulation of epidermal growth factor receptor activity;   downregulation of epidermal growth factor receptor activity;   negative regulation of EGF receptor activity;   negative regulation of EGFR activity;   negative regulation of epidermal growth factor receptor activity
 narrow_synonym: inhibition of epidermal growth factor receptor activity
 alt_id: GO:0007177


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negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBL Cbl proto-oncogene JBrowse link 9 46,416,937 46,512,855 RGD:14298760
G CBLB Cbl proto-oncogene B JBrowse link 13 153,480,525 153,700,115 RGD:14298760
G CBLC Cbl proto-oncogene C JBrowse link 6 51,274,717 51,292,546 RGD:14298760
G CHMP6 charged multivesicular body protein 6 JBrowse link 12 1,691,821 1,698,347 RGD:14298760
G ERRFI1 ERBB receptor feedback inhibitor 1 JBrowse link 6 68,667,651 68,682,629 RGD:14298760
G PSEN1 presenilin 1 JBrowse link 7 96,478,179 96,567,884 RGD:14298760
G SOCS4 suppressor of cytokine signaling 4 JBrowse link 1 184,379,017 184,398,902 RGD:14298760
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 3 93,777,402 93,925,859 RGD:14298760
G VPS25 vacuolar protein sorting 25 homolog JBrowse link 12 20,082,864 20,088,443 RGD:14298760
G ZFYVE28 zinc finger FYVE-type containing 28 JBrowse link 8 1,225,417 1,312,938 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14320
    biological regulation 9567
      regulation of molecular function 2090
        regulation of signaling receptor activity 95
          regulation of epidermal growth factor-activated receptor activity 18
            negative regulation of epidermal growth factor-activated receptor activity 10
Path 2
Term Annotations click to browse term
  biological_process 14320
    metabolic process 8826
      organic substance metabolic process 8295
        macromolecule metabolic process 7115
          protein metabolic process 4358
            protein modification process 2969
              cellular protein modification process 2969
                peptidyl-amino acid modification 936
                  peptidyl-tyrosine modification 265
                    peptidyl-tyrosine phosphorylation 263
                      regulation of peptidyl-tyrosine phosphorylation 177
                        regulation of protein tyrosine kinase activity 65
                          regulation of epidermal growth factor-activated receptor activity 18
                            negative regulation of epidermal growth factor-activated receptor activity 10
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.