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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal growth factor-activated receptor activity
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Accession:GO:0007175 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.
Synonyms:exact_synonym: EGF receptor downregulation;   down regulation of epidermal growth factor receptor activity;   downregulation of epidermal growth factor receptor activity;   negative regulation of EGF receptor activity;   negative regulation of EGFR activity;   negative regulation of epidermal growth factor receptor activity
 narrow_synonym: inhibition of epidermal growth factor receptor activity
 alt_id: GO:0007177


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negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:13792537
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:13792537
G Cblc Cbl proto-oncogene C JBrowse link 1 80,699,321 80,716,146 RGD:1624291
RGD:13792537
G Chmp6 charged multivesicular body protein 6 JBrowse link 10 109,073,678 109,079,348 RGD:1624291
RGD:1600115
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:8553726
RGD:1600115
RGD:1624291
G Gprc5a G protein-coupled receptor, class C, group 5, member A JBrowse link 4 168,832,937 168,851,650 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
RGD:1600115
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
G Socs4 suppressor of cytokine signaling 4 JBrowse link 15 24,056,383 24,070,868 RGD:1624291
RGD:1600115
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
RGD:1600115
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1624291
RGD:1600115
G Vps25 vacuolar protein sorting 25 homolog JBrowse link 10 89,174,684 89,180,165 RGD:1624291
RGD:1600115
G Zfyve28 zinc finger FYVE-type containing 28 JBrowse link 14 81,725,513 81,811,142 RGD:1624291
RGD:13792537
G Zgpat zinc finger CCCH-type and G-patch domain containing JBrowse link 3 176,865,078 176,881,603 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19312
    biological regulation 13339
      regulation of molecular function 3014
        regulation of signaling receptor activity 184
          regulation of epidermal growth factor-activated receptor activity 26
            negative regulation of epidermal growth factor-activated receptor activity 14
Path 2
Term Annotations click to browse term
  biological_process 19312
    metabolic process 11535
      organic substance metabolic process 10932
        macromolecule metabolic process 9412
          protein metabolic process 5975
            protein modification process 3864
              cellular protein modification process 3864
                peptidyl-amino acid modification 1278
                  peptidyl-tyrosine modification 390
                    peptidyl-tyrosine phosphorylation 387
                      regulation of peptidyl-tyrosine phosphorylation 276
                        regulation of protein tyrosine kinase activity 92
                          regulation of epidermal growth factor-activated receptor activity 26
                            negative regulation of epidermal growth factor-activated receptor activity 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.