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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of epidermal growth factor-activated receptor activity
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Accession:GO:0007176 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of EGF-activated receptor activity.
Synonyms:exact_synonym: regulation of EGF receptor activity;   regulation of EGFR activity;   regulation of epidermal growth factor receptor activity


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regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplp2 amyloid beta precursor like protein 2 JBrowse link 8 32,298,526 32,328,821 RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
RGD:1600115
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:13792537
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:13792537
G Cblc Cbl proto-oncogene C JBrowse link 1 80,699,321 80,716,146 RGD:1624291
RGD:13792537
G Chmp6 charged multivesicular body protein 6 JBrowse link 10 109,073,678 109,079,348 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:8553726
RGD:1600115
RGD:1624291
G Gprc5a G protein-coupled receptor, class C, group 5, member A JBrowse link 4 168,832,937 168,851,650 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
G Socs4 suppressor of cytokine signaling 4 JBrowse link 15 24,056,383 24,070,868 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1624291
G Vps25 vacuolar protein sorting 25 homolog JBrowse link 10 89,174,684 89,180,165 RGD:1624291
G Zfyve28 zinc finger FYVE-type containing 28 JBrowse link 14 81,725,513 81,811,142 RGD:1624291
RGD:13792537
G Zgpat zinc finger CCCH-type and G-patch domain containing JBrowse link 3 176,865,078 176,881,603 RGD:1624291
RGD:1600115
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:1624291
RGD:1600115
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:2317913
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:1624291
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1624291
G Epgn epithelial mitogen JBrowse link 14 18,627,103 18,635,135 RGD:1624291
RGD:1600115
G Ereg epiregulin JBrowse link 14 18,577,620 18,591,395 RGD:632743
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:1624291
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:1624291
G Neurl1 neuralized E3 ubiquitin protein ligase 1 JBrowse link 1 266,953,006 267,038,879 RGD:1624291
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    biological regulation 13335
      regulation of molecular function 3020
        regulation of signaling receptor activity 184
          regulation of epidermal growth factor-activated receptor activity 26
            negative regulation of epidermal growth factor-activated receptor activity 14
            positive regulation of epidermal growth factor-activated receptor activity 10
Path 2
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      organic substance metabolic process 10949
        macromolecule metabolic process 9418
          protein metabolic process 5973
            protein modification process 3851
              cellular protein modification process 3851
                peptidyl-amino acid modification 1272
                  peptidyl-tyrosine modification 390
                    peptidyl-tyrosine phosphorylation 387
                      regulation of peptidyl-tyrosine phosphorylation 276
                        regulation of protein tyrosine kinase activity 92
                          regulation of epidermal growth factor-activated receptor activity 26
                            negative regulation of epidermal growth factor-activated receptor activity 14
                            positive regulation of epidermal growth factor-activated receptor activity 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.