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ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor beta receptor complex assembly
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Accession:GO:0007181 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex.
Synonyms:exact_synonym: TGF-beta receptor complex assembly;   TGF-beta:type II receptor:type I receptor complex assembly;   TGFbeta receptor complex assembly


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transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C IDA TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:85,515,610...85,517,516
Ensembl chr 1:85,516,653...85,517,360
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IMP RGD PMID:8106553 RGD:1579949 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    response to stimulus 10568
      response to endogenous stimulus 2026
        cellular response to endogenous stimulus 1618
          cellular response to transforming growth factor beta stimulus 264
            transforming growth factor beta receptor signaling pathway 183
              transforming growth factor beta receptor complex assembly 3
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        regulation of cellular process 12560
          signal transduction 7015
            cell surface receptor signaling pathway 2782
              enzyme linked receptor protein signaling pathway 963
                transmembrane receptor protein serine/threonine kinase signaling pathway 383
                  transforming growth factor beta receptor signaling pathway 183
                    transforming growth factor beta receptor complex assembly 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.