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ONTOLOGY REPORT - ANNOTATIONS


Term:adenylate cyclase-inhibiting dopamine receptor signaling pathway
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Accession:GO:0007195 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
Synonyms:exact_synonym: dopamine receptor, adenylate cyclase inhibiting pathway;   dopamine receptor, adenylyl cyclase inhibiting pathway;   inhibition of adenylate cyclase activity by dopamine receptor signalling pathway
 related_synonym: inhibition of adenylate cyclase activity by dopamine receptor signaling pathway


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adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy5 adenylate cyclase 5 JBrowse link 11 68,695,839 68,842,452 RGD:1624291
RGD:1600115
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:8553953
RGD:13792537
RGD:1624291
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:8554810
RGD:13792537
RGD:1624291
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:1624291
RGD:1600115
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:1624291
RGD:1600115
G LOC500460 similar to olfactory receptor Olr841 JBrowse link 5 64,614,755 64,615,714 RGD:13792537
G Olr1257 olfactory receptor 1257 JBrowse link 8 42,429,993 42,430,928 RGD:13792537
G Olr1320 olfactory receptor 1320 JBrowse link 8 43,628,182 43,629,120 RGD:13792537
G Olr533 olfactory receptor 533 JBrowse link 3 74,574,075 74,575,010 RGD:13792537
G Olr841 olfactory receptor 841 JBrowse link 5 64,621,407 64,622,359 RGD:13792537
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prmt5 protein arginine methyltransferase 5 JBrowse link 15 33,156,508 33,165,893 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    signaling 7108
      signal transduction 6597
        signal transduction involved in cellular response to ammonium ion 108
          dopamine receptor signaling pathway 44
            adenylate cyclase-inhibiting dopamine receptor signaling pathway 11
              negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 0
              positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 1
              regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 18166
    response to stimulus 9928
      response to chemical 6195
        response to nitrogen compound 1512
          response to organonitrogen compound 1420
            response to monoamine 123
              cellular response to monoamine stimulus 114
                cellular response to catecholamine stimulus 114
                  cellular response to dopamine 95
                    dopamine receptor signaling pathway 44
                      adenylate cyclase-inhibiting dopamine receptor signaling pathway 11
                        negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 0
                        positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 1
                        regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.