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ONTOLOGY REPORT - ANNOTATIONS


Term:adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
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Accession:GO:0007197 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
Synonyms:exact_synonym: muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway;   muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway
 related_synonym: inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway;   inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway;   inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signalling pathway


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adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrm1 cholinergic receptor, muscarinic 1 JBrowse link 1 224,869,087 224,885,101 RGD:13792537
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:13792537
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:13792537
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:1624291
RGD:1600115
RGD:13792537
G Chrm5 cholinergic receptor, muscarinic 5 JBrowse link 3 103,966,451 104,018,815 RGD:13792537
G Hrh3 histamine receptor H3 JBrowse link 3 175,474,310 175,479,395 RGD:13792537
G Hrh4 histamine receptor H4 JBrowse link 18 4,365,429 4,382,599 RGD:13792537
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:8656009

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    cellular process 17226
      signal transduction 6875
        G protein-coupled receptor signaling pathway 2474
          G protein-coupled acetylcholine receptor signaling pathway 14
            adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 8
              adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate 0
Path 2
Term Annotations click to browse term
  biological_process 19317
    response to stimulus 10411
      response to chemical 6308
        response to nitrogen compound 1523
          response to ammonium ion 248
            response to acetylcholine 34
              cellular response to acetylcholine 34
                acetylcholine receptor signaling pathway 32
                  G protein-coupled acetylcholine receptor signaling pathway 14
                    adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 8
                      adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.