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Term:activation of phospholipase C activity
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Accession:GO:0007202 term browser browse the term
Definition:The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.
Comment:Note that this term refers to a signaling pathway, and should not be confused with function terms such as 'phospholipase activator activity ; GO:0016004'.
Synonyms:exact_synonym: phospholipase C activation

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activation of phospholipase C activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1r1 ADCYAP receptor type I JBrowse link 4 85,662,809 85,711,696 RGD:631732
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:69745
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:1582152
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:1624291
G Arhgap6 Rho GTPase activating protein 6 JBrowse link X 26,314,561 26,845,242 RGD:1624291
G Calcr calcitonin receptor JBrowse link 4 28,627,439 28,702,559 RGD:1624291
G Dlc1 DLC1 Rho GTPase activating protein JBrowse link 16 58,776,489 59,247,752 RGD:68218
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:1598489
G Gpr55 G protein-coupled receptor 55 JBrowse link 9 92,961,431 93,011,157 RGD:1624291
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:1624291
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
G Itk IL2-inducible T-cell kinase JBrowse link 10 31,431,820 31,493,413 RGD:1624291
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:1624291
G Ms4a2 membrane spanning 4-domains A2 JBrowse link 1 227,957,363 227,965,312 RGD:1599963
G Nmur1 neuromedin U receptor 1 JBrowse link 9 93,402,871 93,407,264 RGD:1624291
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:1624291
G Sele selectin E JBrowse link 13 82,355,234 82,365,323 RGD:1624291
G Txk TXK tyrosine kinase JBrowse link 14 38,029,809 38,085,822 RGD:1624291

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  biological_process 18166
    biological regulation 12793
      regulation of molecular function 2919
        regulation of catalytic activity 2211
          regulation of hydrolase activity 1233
            regulation of lipase activity 77
              regulation of phospholipase activity 57
                positive regulation of phospholipase activity 44
                  positive regulation of phospholipase C activity 27
                    activation of phospholipase C activity 18
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.