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ONTOLOGY REPORT - ANNOTATIONS


Term:protein kinase C-activating G protein-coupled receptor signaling pathway
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Accession:GO:0007205 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
Synonyms:related_synonym: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;   activation of protein kinase C activity by G-protein coupled receptor protein signalling pathway


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protein kinase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1625697
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:1625754
G Cck cholecystokinin JBrowse link 8 130,120,525 130,127,515 RGD:1626097
G Cish cytokine inducible SH2-containing protein JBrowse link 8 116,054,547 116,059,494 RGD:1624291
RGD:1600115
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:5130951
G Dgka diacylglycerol kinase, alpha JBrowse link 7 3,143,826 3,170,764 RGD:1600115
G Dgkb diacylglycerol kinase, beta JBrowse link 6 57,516,351 58,277,385 RGD:1600115
G Dgkd diacylglycerol kinase, delta JBrowse link 9 94,980,328 95,071,531 RGD:1600115
G Dgke diacylglycerol kinase epsilon JBrowse link 10 76,375,981 76,408,224 RGD:1600115
G Dgkg diacylglycerol kinase, gamma JBrowse link 11 81,971,585 82,165,111 RGD:1298876
G Dgkh diacylglycerol kinase, eta JBrowse link 15 60,791,574 60,967,236 RGD:1624291
RGD:1600115
G Dgki diacylglycerol kinase, iota JBrowse link 4 64,365,115 64,831,473 RGD:1600115
G Dgkk diacylglycerol kinase kappa JBrowse link X 16,441,318 16,526,046 RGD:1600115
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1600115
G Dgkz diacylglycerol kinase zeta JBrowse link 3 80,844,002 80,886,487 RGD:1600115
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
RGD:1600115
G Edn2 endothelin 2 JBrowse link 5 139,098,472 139,106,396 RGD:1581817
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:728499
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1582293
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:728711
RGD:8554618
G Hcrt hypocretin neuropeptide precursor JBrowse link 10 88,669,216 88,670,430 RGD:1600968
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:1624291
RGD:1600115
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1600108
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:1625020
G Ms4a2 membrane spanning 4-domains A2 JBrowse link 1 227,957,363 227,965,312 RGD:1599963
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:1600115
RGD:1624291
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:68785

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    signaling 7108
      signal transduction 6597
        G protein-coupled receptor signaling pathway 2395
          protein kinase C-activating G protein-coupled receptor signaling pathway 28
Path 2
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological process 12128
        regulation of cellular process 11458
          signal transduction 6597
            G protein-coupled receptor signaling pathway 2395
              protein kinase C-activating G protein-coupled receptor signaling pathway 28
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.