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ONTOLOGY REPORT - ANNOTATIONS


Term:protein kinase C-activating G protein-coupled receptor signaling pathway
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Accession:GO:0007205 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
Synonyms:related_synonym: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway;   activation of protein kinase C activity by G-protein coupled receptor protein signalling pathway


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protein kinase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2a adenosine A2a receptor JBrowse link NW_004955455 7,886,720 7,906,214 RGD:9068941
G Bdkrb1 bradykinin receptor B1 JBrowse link NW_004955438 16,500,219 16,505,394 RGD:9068941
G Cck cholecystokinin JBrowse link NW_004955420 28,438,806 28,443,458 RGD:9068941
G Chrm1 cholinergic receptor muscarinic 1 JBrowse link NW_004955599 349,744 356,714 RGD:9068941
G Cish cytokine inducible SH2 containing protein JBrowse link NW_004955532 2,380,380 2,386,000 RGD:9068941
G Dgka diacylglycerol kinase alpha JBrowse link NW_004955458 3,517,519 3,544,651 RGD:9068941
G Dgkb diacylglycerol kinase beta JBrowse link NW_004955410 17,677,375 18,304,409 RGD:9068941
G Dgkd diacylglycerol kinase delta JBrowse link NW_004955453 2,740,922 2,802,669 RGD:9068941
G Dgke diacylglycerol kinase epsilon JBrowse link NW_004955451 5,966,773 5,988,004 RGD:9068941
G Dgkg diacylglycerol kinase gamma JBrowse link NW_004955420 21,296,515 21,481,651 RGD:9068941
G Dgkh diacylglycerol kinase eta JBrowse link NW_004955518 4,104,700 4,263,657 RGD:9068941
G Dgki diacylglycerol kinase iota JBrowse link NW_004955494 5,119,419 5,541,058 RGD:9068941
G Dgkk diacylglycerol kinase kappa JBrowse link NW_004955543 1,468,328 1,601,101 RGD:9068941
G Dgkq diacylglycerol kinase theta JBrowse link NW_004955514 452,548 475,240 RGD:9068941
G Dgkz diacylglycerol kinase zeta JBrowse link NW_004955422 1,658,237 1,687,000 RGD:9068941
G Edn1 endothelin 1 JBrowse link NW_004955465 2,287,906 2,314,945 RGD:9068941
G F2r coagulation factor II thrombin receptor JBrowse link NW_004955425 24,144,905 24,164,498 RGD:9068941
G Gap43 growth associated protein 43 JBrowse link NW_004955427 15,696,549 15,791,279 RGD:9068941
G Hcrt hypocretin neuropeptide precursor JBrowse link NW_004955451 16,235,819 16,237,457 RGD:9068941
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link NW_004955502 5,640,919 5,646,899 RGD:9068941
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link NW_004955453 4,352,278 4,367,807 RGD:9068941
G Il2 interleukin 2 JBrowse link NW_004955428 18,163,010 18,168,157 RGD:9068941
G Lrp1 LDL receptor related protein 1 JBrowse link NW_004955458 4,861,431 4,941,939 RGD:9068941
G Pard3 par-3 family cell polarity regulator JBrowse link NW_004955462 2,930,171 3,457,358 RGD:9068941
G Pick1 protein interacting with PRKCA 1 JBrowse link NW_004955413 24,383,130 24,399,092 RGD:9068941
G Plpp1 phospholipid phosphatase 1 JBrowse link NW_004955446 12,201,678 12,279,992 RGD:9068941
G Prkd3 protein kinase D3 JBrowse link NW_004955441 5,051,079 5,112,791 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14516
    signaling 5613
      signal transduction 5166
        G protein-coupled receptor signaling pathway 891
          protein kinase C-activating G protein-coupled receptor signaling pathway 27
Path 2
Term Annotations click to browse term
  biological_process 14516
    biological regulation 10313
      regulation of biological process 9748
        regulation of cellular process 9144
          signal transduction 5166
            G protein-coupled receptor signaling pathway 891
              protein kinase C-activating G protein-coupled receptor signaling pathway 27
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.