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ONTOLOGY REPORT - ANNOTATIONS


Term:gamma-aminobutyric acid signaling pathway
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Accession:GO:0007214 term browser browse the term
Definition:The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.
Synonyms:exact_synonym: 4-aminobutanoate signaling pathway;   4-aminobutanoate signalling pathway;   4-aminobutyrate signaling pathway;   4-aminobutyrate signalling pathway;   GABA signaling pathway;   GABA signalling pathway;   gamma-aminobutyric acid signalling pathway


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gamma-aminobutyric acid signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 ISO RGD PMID:10924501 RGD:631878 NCBI chrNW_004955413:25,406,589...25,408,727
Ensembl chrNW_004955413:25,406,589...25,412,218
JBrowse link
G Bdnf brain derived neurotrophic factor ISO (MGI:MGI:3694324|PMID:16754670) MGI PMID:16754670 MGI:MGI:3694324 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO (MGI:MGI:79685|PMID:8565963) MGI PMID:8565963 MGI:MGI:79685 NCBI chrNW_004955415:32,182,536...32,457,511
Ensembl chrNW_004955415:32,183,442...32,400,595
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 ISO (MGI:MGI:52881|PMID:8388308), (MGI:MGI:77305|PMID:7472490), (MGI:MGI:77739|PMID:7562514) MGI PMID:7472490, PMID:7562514, PMID:8388308 MGI:MGI:52881, MGI:MGI:77305, MGI:MGI:77739 NCBI chrNW_004955440:17,364,996...17,497,446 JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO (PMID:9872316)
(MGI:MGI:4462115|PMID:20400944)
UniProtKB
MGI
PMID:9872316, PMID:20400944 MGI:MGI:4462115 NCBI chrNW_004955583:85,255...115,140
Ensembl chrNW_004955583:85,255...115,189
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 ISO (PMID:9872316) UniProtKB
RGD
PMID:9872316, PMID:11389174 RGD:632824 NCBI chrNW_004955419:26,872,734...27,241,917
Ensembl chrNW_004955419:26,872,728...27,239,464
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor alpha2 subunit ISO (PMID:8391122) UniProtKB PMID:8391122 NCBI chrNW_004955443:2,042,202...2,176,589
Ensembl chrNW_004955443:2,042,151...2,179,174
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor beta1 subunit ISO (PMID:26950270) UniProtKB PMID:26950270 NCBI chrNW_004955443:1,126,223...1,514,291
Ensembl chrNW_004955443:1,132,860...1,514,376
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor beta2 subunit ISO (PMID:27789573) UniProtKB PMID:27789573 NCBI chrNW_004955408:15,126,235...15,363,169
Ensembl chrNW_004955408:15,131,909...15,363,169
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor beta3 subunit ISO (PMID:26950270) UniProtKB PMID:26950270 NCBI chrNW_004955533:2,879,437...2,938,952
Ensembl chrNW_004955533:2,573,599...2,938,952
JBrowse link
G Gabre gamma-aminobutyric acid type A receptor epsilon subunit ISO RGD PMID:11691872 RGD:727328 NCBI chrNW_004955498:7,470,881...7,488,902 JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor gamma2 subunit ISO (MGI:MGI:2450227|PMID:12574411) MGI PMID:12574411 MGI:MGI:2450227 NCBI chrNW_004955408:15,766,161...15,857,121
Ensembl chrNW_004955408:15,765,984...15,857,244
JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:11923410 RGD:625670 NCBI chrNW_004955532:2,059,038...2,079,120
Ensembl chrNW_004955532:2,059,038...2,079,957
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO (MGI:MGI:3830611|PMID:16925594) MGI PMID:16925594 MGI:MGI:3830611 NCBI chrNW_004955446:4,913,181...4,917,726
Ensembl chrNW_004955446:4,913,884...4,915,146
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 ISO RGD PMID:11986365 RGD:727368 NCBI chrNW_004955415:5,745,056...5,802,409
Ensembl chrNW_004955415:5,685,309...5,802,409
JBrowse link
G Phf24 PHD finger protein 24 ISO (MGI:MGI:5616490|PMID:25242222) MGI PMID:25242222 MGI:MGI:5616490 NCBI chrNW_004955472:1,186,021...1,204,018
Ensembl chrNW_004955472:1,185,110...1,204,040
JBrowse link
G Plcl1 phospholipase C like 1 (inactive) ISO (MGI:MGI:3694324|PMID:16754670) MGI PMID:16754670 MGI:MGI:3694324 NCBI chrNW_004955403:2,643,092...2,904,651
Ensembl chrNW_004955403:2,641,360...2,693,352
JBrowse link
G Plcl2 phospholipase C like 2 ISO (MGI:MGI:3694324|PMID:16754670) MGI PMID:16754670 MGI:MGI:3694324 NCBI chrNW_004955430:9,157,074...9,347,366
Ensembl chrNW_004955430:9,157,074...9,348,563
JBrowse link
G Shisa7 shisa family member 7 ISO (MGI:MGI:6377643|PMID:31601770) UniProt PMID:31601770 MGI:MGI:6377643 NCBI chrNW_004955567:840,193...845,093 JBrowse link
G Slc12a2 solute carrier family 12 member 2 ISO PMID:16227993 ARUK-UCL
RGD
PMID:15090604, PMID:16227993 RGD:1580436, RGD:1580584 NCBI chrNW_004955415:1,138,297...1,219,241
Ensembl chrNW_004955415:1,137,327...1,219,241
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11889
    signaling 4142
      signal transduction 3676
        G protein-coupled receptor signaling pathway 449
          gamma-aminobutyric acid signaling pathway 20
Path 2
Term Annotations click to browse term
  biological_process 11889
    biological regulation 8722
      regulation of biological process 8267
        regulation of cellular process 7843
          signal transduction 3676
            G protein-coupled receptor signaling pathway 449
              gamma-aminobutyric acid signaling pathway 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.