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ONTOLOGY REPORT - ANNOTATIONS


Term:gamma-aminobutyric acid signaling pathway
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Accession:GO:0007214 term browser browse the term
Definition:The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.
Synonyms:exact_synonym: 4-aminobutanoate signaling pathway;   4-aminobutanoate signalling pathway;   4-aminobutyrate signaling pathway;   4-aminobutyrate signalling pathway;   GABA signaling pathway;   GABA signalling pathway;   gamma-aminobutyric acid signalling pathway


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gamma-aminobutyric acid signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 IDA RGD PMID:10924501 RGD:631878 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO (MGI:3694324|PMID:16754670) RGD PMID:16754670 MGI:3694324 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA
ISO
GO_REF:0000107
MGI:1856209 (MGI:79685|PMID:8565963)
Ensembl
RGD
PMID:8565963 GO_REF:0000107, MGI:79685 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 ISO MGI:1856936 (MGI:52881|PMID:8388308), (MGI:77305|PMID:7472490), (MGI:77739|PMID:7562514) RGD PMID:7472490, PMID:7562514, PMID:8388308 MGI:52881, MGI:77305, MGI:77739 NCBI chr 3:37,950,846...38,211,478
Ensembl chr 3:37,955,069...38,090,526
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:4462115|PMID:20400944)
PMID:21873635
GO_REF:0000024
(PMID:9872316)
Ensembl
RGD
UniProt
PMID:9872316, PMID:20400944, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:4462115, RGD:13792537 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 IDA
IBA
ISO
IEA
PMID:21873635
(PMID:9872316)
GO_REF:0000107
RGD
Ensembl
PMID:9872316, PMID:11389174, PMID:21873635 GO_REF:0000107, RGD:632824, RGD:13792537 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 IEA
IBA
ISO
GO_REF:0000002
PMID:21873635
(PMID:8391122)
InterPro
RGD
PMID:8391122, PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr14:39,662,411...39,801,082
Ensembl chr14:39,661,968...39,798,302
JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:152,414,332...152,642,607
Ensembl chr  X:152,414,615...152,642,531
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:112,833,941...112,947,482
Ensembl chr 1:112,833,944...112,947,451
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 TAS
ISS
ISO
GO_REF:0000024
(PMID:26950270)
UniProt
RGD
PMID:26950270, PMID:11986365 GO_REF:0000024, RGD:727368 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 TAS
ISO
(PMID:27789573) RGD PMID:27789573, PMID:11877425 RGD:727351 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:26950270)
Ensembl
UniProt
RGD
PMID:26950270 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11691872, PMID:21873635 RGD:727328, RGD:13792537 NCBI chr  X:152,220,180...152,237,347
Ensembl chr  X:152,218,707...152,237,361
JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:39,964,502...40,051,306
Ensembl chr14:39,964,588...40,049,354
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 TAS
ISO
IBA
IEA
(MGI:2450227|PMID:12574411)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:12574411, PMID:1702644, PMID:21873635 GO_REF:0000107, MGI:2450227, RGD:728419, RGD:13792537 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 TAS
IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:1311098, PMID:21873635 GO_REF:0000002, RGD:727524, RGD:13792537 NCBI chr 1:112,158,525...112,812,267
Ensembl chr 1:112,158,519...112,811,936
JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 ISO MGI:2446461 (MGI:2179933|PMID:12019334) RGD PMID:12019334 MGI:2179933 NCBI chr 5:48,303,366...48,341,571
Ensembl chr 5:48,303,366...48,341,642
JBrowse link
G Gnai2 G protein subunit alpha i2 IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11923410, PMID:21873635 RGD:625670, RGD:13792537 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gpr156 G protein-coupled receptor 156 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:65,285,468...65,350,442
Ensembl chr11:65,285,468...65,350,442
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO MGI:2387408 (MGI:3830611|PMID:16925594) RGD PMID:16925594 MGI:3830611 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 IMP RGD PMID:11986365 RGD:727368 NCBI chr18:57,637,013...57,820,317
Ensembl chr18:57,654,290...57,819,698
JBrowse link
G Phf24 PHD finger protein 24 ISO MGI:5706936 (MGI:5616490|PMID:25242222) RGD PMID:25242222 MGI:5616490 NCBI chr 5:58,359,744...58,387,446
Ensembl chr 5:58,359,498...58,383,070
JBrowse link
G Plcl1 phospholipase C-like 1 IEA
ISO
GO_REF:0000107
MGI:1352756 (MGI:3694324|PMID:16754670)
Ensembl
RGD
PMID:16754670 GO_REF:0000107, MGI:3694324 NCBI chr 9:62,016,112...62,349,244
Ensembl chr 9:62,291,405...62,349,309
JBrowse link
G Plcl2 phospholipase C-like 2 ISO MGI:3036262 (MGI:3694324|PMID:16754670) RGD PMID:16754670 MGI:3694324 NCBI chr 9:1,782,536...1,984,654
Ensembl chr 9:1,782,536...1,984,654
JBrowse link
G Shisa7 shisa family member 7 ISO (MGI:6377643|PMID:31601770) RGD PMID:31601770 MGI:6377643 NCBI chr 1:72,545,413...72,564,513
Ensembl chr 1:72,545,596...72,564,513
JBrowse link
G Slc12a2 solute carrier family 12 member 2 IEP
IMP
PMID:16227993 RGD
ARUK-UCL
PMID:15090604, PMID:16227993 RGD:1580436, RGD:1580584 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    signaling 7579
      signal transduction 7010
        G protein-coupled receptor signaling pathway 2509
          gamma-aminobutyric acid signaling pathway 29
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          signal transduction 7010
            G protein-coupled receptor signaling pathway 2509
              gamma-aminobutyric acid signaling pathway 29
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.