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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled glutamate receptor signaling pathway
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Accession:GO:0007216 term browser browse the term
Definition:A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: metabotropic glutamate receptor signaling pathway;   metabotropic glutamate receptor signalling pathway


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G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dagla diacylglycerol lipase, alpha JBrowse link 1 226,297,013 226,353,712 RGD:1624291
RGD:13792537
G Daglb diacylglycerol lipase, beta JBrowse link 12 13,113,073 13,157,748 RGD:13792537
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:625670
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:1624291
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:1304458
RGD:1600115
RGD:13792537
RGD:1624291
G Grm2 glutamate metabotropic receptor 2 JBrowse link 8 115,344,999 115,358,628 RGD:13792537
G Grm3 glutamate metabotropic receptor 3 JBrowse link 4 21,316,761 21,567,561 RGD:13792537
G Grm4 glutamate metabotropic receptor 4 JBrowse link 20 6,745,682 6,791,521 RGD:13792537
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:8553991
RGD:13792537
RGD:1600115
RGD:1624291
RGD:12050103
G Grm6 glutamate metabotropic receptor 6 JBrowse link 10 36,345,503 36,363,416 RGD:1624291
RGD:13792537
RGD:1600115
G Grm7 glutamate metabotropic receptor 7 JBrowse link 4 142,452,616 143,368,460 RGD:13792537
G Grm8 glutamate metabotropic receptor 8 JBrowse link 4 54,474,344 55,409,526 RGD:13792537
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:633021
RGD:13792537
G Homer2 homer scaffold protein 2 JBrowse link 1 143,443,300 143,535,579 RGD:13792537
G Homer3 homer scaffold protein 3 JBrowse link 16 20,880,447 20,890,968 RGD:13792537
G Trpm1 transient receptor potential cation channel, subfamily M, member 1 JBrowse link 1 124,983,391 125,101,759 RGD:1600115
RGD:1624291
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:1600115
G Grm2 glutamate metabotropic receptor 2 JBrowse link 8 115,344,999 115,358,628 RGD:1600115
G Grm3 glutamate metabotropic receptor 3 JBrowse link 4 21,316,761 21,567,561 RGD:1600115
G Grm4 glutamate metabotropic receptor 4 JBrowse link 20 6,745,682 6,791,521 RGD:1624291
RGD:1600115
G Grm6 glutamate metabotropic receptor 6 JBrowse link 10 36,345,503 36,363,416 RGD:69945
G Grm7 glutamate metabotropic receptor 7 JBrowse link 4 142,452,616 143,368,460 RGD:728749
RGD:1600115
RGD:1624291
G Grm8 glutamate metabotropic receptor 8 JBrowse link 4 54,474,344 55,409,526 RGD:6484727
RGD:1600115
RGD:1624291
phospholipase C-activating G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:728711
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:625594
RGD:728711

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    signaling 7108
      signal transduction 6597
        G protein-coupled receptor signaling pathway 2395
          G protein-coupled glutamate receptor signaling pathway 16
            adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway 7
            phospholipase C-activating G protein-coupled glutamate receptor signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological process 12128
        regulation of cellular process 11458
          signal transduction 6597
            cell surface receptor signaling pathway 2535
              glutamate receptor signaling pathway 104
                G protein-coupled glutamate receptor signaling pathway 16
                  adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway 7
                  phospholipase C-activating G protein-coupled glutamate receptor signaling pathway 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.