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ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway
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Accession:GO:0007224 term browser browse the term
Definition:A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
Synonyms:exact_synonym: hedgehog signaling pathway;   smoothened signalling pathway
 narrow_synonym: Sonic hedgehog signaling pathway;   hh signaling pathway;   hh signalling pathway
 related_synonym: Shh signaling pathway
 xref: MIPS_funcat:30.05.02.16;   Wikipedia:Hedgehog_signaling_pathway


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smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arl13b ADP-ribosylation factor like GTPase 13B JBrowse link 7 1,122,567 1,188,209 RGD:1624291
G Arl3 ADP ribosylation factor like GTPase 3 JBrowse link 1 266,287,015 266,333,099 RGD:1624291
RGD:1600115
G B9d1 B9 domain containing 1 JBrowse link 10 47,784,294 47,794,399 RGD:1624291
RGD:1600115
G Bbs7 Bardet-Biedl syndrome 7 JBrowse link 2 123,283,402 123,322,991 RGD:1624291
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Boc BOC cell adhesion associated, oncogene regulated JBrowse link 11 61,084,216 61,159,220 RGD:1624291
G Cc2d2a coiled-coil and C2 domain containing 2A JBrowse link 14 71,895,128 71,979,452 RGD:1624291
G Cdon cell adhesion associated, oncogene regulated JBrowse link 8 36,625,757 36,712,091 RGD:8554425
RGD:1600115
RGD:1624291
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
G Cfap410 cilia and flagella associated protein 410 JBrowse link 20 11,417,428 11,424,301 RGD:1624291
G Cluap1 clusterin associated protein 1 JBrowse link 10 11,847,058 11,878,792 RGD:1624291
G Dhh desert hedgehog signaling molecule JBrowse link 7 140,575,288 140,580,783 RGD:634737
RGD:13792537
RGD:1624291
G Disp1 dispatched RND transporter family member 1 JBrowse link 13 101,451,932 101,597,570 RGD:1624291
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 JBrowse link 7 61,785,423 61,816,775 RGD:1624291
G Dzip1 DAZ interacting zinc finger protein 1 JBrowse link 15 104,117,551 104,168,574 RGD:1624291
G Dzip1l DAZ interacting zinc finger protein 1-like JBrowse link 8 107,875,659 107,916,298 RGD:1624291
RGD:1600115
G Evc EvC ciliary complex subunit 1 JBrowse link 14 78,213,601 78,253,266 RGD:1600115
G Evc2 EvC ciliary complex subunit 2 JBrowse link 14 78,128,620 78,212,394 RGD:1624291
G Fkbp8 FKBP prolyl isomerase 8 JBrowse link 16 20,645,956 20,652,890 RGD:1624291
G Foxf1 forkhead box F1 JBrowse link 19 53,012,306 53,016,100 RGD:1624291
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1303367
RGD:1624291
G Gpc2 glypican 2 JBrowse link 12 19,593,041 19,599,374 RGD:5510027
RGD:13792537
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:1624291
RGD:1600115
G Hhat hedgehog acyltransferase JBrowse link 13 111,235,325 111,489,075 RGD:1624291
G Hipk1 homeodomain interacting protein kinase 1 JBrowse link 2 206,224,015 206,274,910 RGD:1624291
RGD:13792537
RGD:1600115
G Hipk2 homeodomain interacting protein kinase 2 JBrowse link 4 66,438,390 66,625,183 RGD:1624291
RGD:13792537
G Hspb11 heat shock protein family B (small), member 11 JBrowse link 5 126,856,128 126,882,913 RGD:1624291
G Hspg2 heparan sulfate proteoglycan 2 JBrowse link 5 155,812,096 155,913,751 RGD:5510033
G Ift172 intraflagellar transport 172 JBrowse link 6 26,390,686 26,485,459 RGD:1624291
G Ift20 intraflagellar transport 20 JBrowse link 10 65,805,808 65,811,353 RGD:1624291
G Ift27 intraflagellar transport 27 JBrowse link 7 119,393,384 119,409,710 RGD:1624291
G Ift46 intraflagellar transport 46 JBrowse link 8 49,075,978 49,097,689 RGD:1624291
G Ift52 intraflagellar transport 52 JBrowse link 3 159,388,868 159,413,358 RGD:1624291
G Ift57 intraflagellar transport 57 JBrowse link 11 53,664,638 53,731,779 RGD:1624291
G Ift80 intraflagellar transport 80 JBrowse link 2 165,506,878 165,600,748 RGD:1624291
G Ift88 intraflagellar transport 88 JBrowse link 15 37,690,417 37,786,855 RGD:1624291
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
RGD:13792537
G Iqub IQ motif and ubiquitin domain containing JBrowse link 4 51,482,169 51,586,881 RGD:1624291
G Kif3a kinesin family member 3a JBrowse link 10 38,918,705 38,953,958 RGD:1624291
G LOC100912537 tectonic-3-like JBrowse link 1 259,096,641 259,107,087 RGD:13792537
G LOC108348055 B9 domain-containing protein 1 JBrowse link 10 49,019,745 49,029,851 RGD:1600115
G LOC690035 similar to Protein KIAA0586 JBrowse link 6 93,562,775 93,667,857 RGD:1624291
RGD:13792537
G Map3k10 mitogen activated protein kinase kinase kinase 10 JBrowse link 1 84,473,178 84,491,689 RGD:1624291
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1624291
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:1624291
G Nsdhl NAD(P) dependent steroid dehydrogenase-like JBrowse link X 152,933,118 152,964,399 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:2311195
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel JBrowse link 1 263,922,201 263,959,318 RGD:1624291
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
RGD:13792537
RGD:1600115
G Ptch2 patched 2 JBrowse link 5 135,962,252 135,983,816 RGD:13792537
G Ptchd1 patched domain containing 1 JBrowse link X 42,558,912 42,610,430 RGD:1624291
G Ptpdc1 protein tyrosine phosphatase domain containing 1 JBrowse link 17 16,333,369 16,381,887 RGD:1624291
G Ro60 Ro60, Y RNA binding protein JBrowse link 13 60,546,892 60,567,882 RGD:1624291
G Ror2 receptor tyrosine kinase-like orphan receptor 2 JBrowse link 17 11,953,552 12,134,386 RGD:1624291
G Septin2 septin 2 JBrowse link 9 100,624,876 100,658,053 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:13792537
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1600115
RGD:13792537
RGD:1624291
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
RGD:13792537
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
G Tbc1d32 TBC1 domain family, member 32 JBrowse link 20 37,463,879 37,701,268 RGD:1624291
G Tctn2 tectonic family member 2 JBrowse link 12 37,400,896 37,427,256 RGD:1624291
RGD:13792537
RGD:1600115
G Tctn3 tectonic family member 3 JBrowse link 1 259,681,435 259,691,881 RGD:1624291
RGD:13792537
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
G Tmem17 transmembrane protein 17 JBrowse link 14 107,268,235 107,308,546 RGD:1624291
RGD:1600115
G Tmem231 transmembrane protein 231 JBrowse link 19 44,137,444 44,158,624 RGD:1624291
RGD:1600115
G Ttbk2 tau tubulin kinase 2 JBrowse link 3 112,677,932 112,789,615 RGD:1624291
G Ttc21b tetratricopeptide repeat domain 21B JBrowse link 3 52,286,794 52,361,060 RGD:1624291
G Ttc26 tetratricopeptide repeat domain 26 JBrowse link 4 66,090,178 66,147,998 RGD:1600115
RGD:1624291
G Wdpcp WD repeat containing planar cell polarity effector JBrowse link 14 106,393,959 106,759,511 RGD:1624291
RGD:1600115
G Wdr19 WD repeat domain 19 JBrowse link 14 44,705,012 44,767,120 RGD:1624291
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:1624291
ciliary receptor clustering involved in smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ift122 intraflagellar transport 122 JBrowse link 4 147,756,574 147,826,983 RGD:1624291
G Nme7 NME/NM23 family member 7 JBrowse link 13 82,607,844 82,737,383 RGD:1624291
G Ssna1 SS nuclear autoantigen 1 JBrowse link 3 2,489,017 2,490,481 RGD:1624291
G Wdr19 WD repeat domain 19 JBrowse link 14 44,705,012 44,767,120 RGD:1624291
mesenchymal smoothened signaling pathway involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
negative regulation of hh target transcription factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:1600115
RGD:1624291
negative regulation of smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd3e CD3e molecule JBrowse link 8 49,297,604 49,309,370 RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:1624291
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Glis2 GLIS family zinc finger 2 JBrowse link 10 11,154,459 11,177,063 RGD:1624291
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:1600115
RGD:1624291
G Gpr37l1 G protein-coupled receptor 37-like 1 JBrowse link 13 51,985,698 51,992,547 RGD:1624291
RGD:1600115
G Hhip Hedgehog-interacting protein JBrowse link 19 31,525,134 31,614,487 RGD:1624291
G Ift122 intraflagellar transport 122 JBrowse link 4 147,756,574 147,826,983 RGD:1624291
G Kctd11 potassium channel tetramerization domain containing 11 JBrowse link 10 56,489,552 56,491,715 RGD:1624291
G Kctd21 potassium channel tetramerization domain containing 21 JBrowse link 1 162,307,746 162,325,284 RGD:1624291
RGD:1600115
G Kctd6 potassium channel tetramerization domain containing 6 JBrowse link 15 18,484,607 18,493,188 RGD:1624291
G Kif7 kinesin family member 7 JBrowse link 1 141,434,183 141,452,592 RGD:1624291
G Megf8 multiple EGF-like-domains 8 JBrowse link 1 82,184,671 82,234,045 RGD:1600115
RGD:1624291
G Mgrn1 mahogunin ring finger 1 JBrowse link 10 10,832,573 10,881,999 RGD:1600115
RGD:1624291
G Mosmo modulator of smoothened JBrowse link 1 190,604,613 190,671,906 RGD:1624291
RGD:13792537
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:1624291
RGD:1600115
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
G Sall3 spalt-like transcription factor 3 JBrowse link 18 77,572,200 77,591,710 RGD:1624291
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:1624291
RGD:1600115
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
G Ulk3 unc-51 like kinase 3 JBrowse link 8 62,368,548 62,375,229 RGD:1624291
RGD:1600115
G Wnt7b Wnt family member 7B JBrowse link 7 126,423,418 126,465,724 RGD:1624291
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr161 G protein-coupled receptor 161 JBrowse link 13 83,530,389 83,576,117 RGD:1624291
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1624291
RGD:1600115
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:1624291
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
G Traf3ip1 TRAF3 interacting protein 1 JBrowse link 9 98,621,499 98,658,223 RGD:1624291
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ift122 intraflagellar transport 122 JBrowse link 4 147,756,574 147,826,983 RGD:1624291
G Rfx4 regulatory factor X4 JBrowse link 7 25,831,358 25,909,976 RGD:1624291
RGD:13792537
G Rfx8 RFX family member 8, lacking RFX DNA binding domain JBrowse link 9 46,414,407 46,476,076 RGD:13792537
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
patched ligand maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Disp1 dispatched RND transporter family member 1 JBrowse link 13 101,451,932 101,597,570 RGD:1624291
positive regulation of hh target transcription factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Stk36 serine/threonine kinase 36 JBrowse link 9 81,880,175 81,908,014 RGD:1624291
RGD:13792537
positive regulation of smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Armc9 armadillo repeat containing 9 JBrowse link 9 93,172,718 93,299,119 RGD:1600115
RGD:1624291
G Chsy1 chondroitin sulfate synthase 1 JBrowse link 1 127,010,587 127,071,570 RGD:1624291
G Cibar1 CBY1 interacting BAR domain containing 1 JBrowse link 5 25,732,457 25,750,953 RGD:1600115
RGD:1624291
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:1624291
G Dcdc2 doublecortin domain containing 2 JBrowse link 17 41,838,201 42,031,265 RGD:1624291
G Dlg5 discs large MAGUK scaffold protein 5 JBrowse link 15 120,213 230,312 RGD:1624291
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 JBrowse link 8 5,217,054 5,436,969 RGD:1624291
RGD:1600115
G Evc EvC ciliary complex subunit 1 JBrowse link 14 78,213,601 78,253,266 RGD:1624291
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:1624291
G Gas8 growth arrest specific 8 JBrowse link 19 56,316,367 56,335,873 RGD:1600115
RGD:1624291
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:1624291
RGD:1600115
G Ift172 intraflagellar transport 172 JBrowse link 6 26,390,686 26,485,459 RGD:1624291
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
G Intu inturned planar cell polarity protein JBrowse link 2 127,589,325 127,611,705 RGD:1624291
RGD:1600115
G Kif7 kinesin family member 7 JBrowse link 1 141,434,183 141,452,592 RGD:1624291
G Ndst1 N-deacetylase and N-sulfotransferase 1 JBrowse link 18 55,951,497 56,014,107 RGD:1624291
G Pdcl phosducin-like JBrowse link 3 21,602,349 21,609,821 RGD:1600115
RGD:1624291
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316785
G Prrx1 paired related homeobox 1 JBrowse link 13 81,147,038 81,215,559 RGD:1624291
G Prrx2 paired related homeobox 2 JBrowse link 3 9,681,871 9,718,051 RGD:1624291
G Rab34 RAB34, member RAS oncogene family JBrowse link 10 65,448,111 65,452,178 RGD:1600115
RGD:1624291
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 JBrowse link 7 124,501,988 124,620,755 RGD:1624291
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 JBrowse link 1 174,428,056 174,495,356 RGD:1624291
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 JBrowse link 20 7,718,260 7,749,847 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Shox2 short stature homeobox 2 JBrowse link 2 164,118,175 164,126,783 RGD:1624291
G Skor2 SKI family transcriptional corepressor 2 JBrowse link 18 73,145,596 73,199,395 RGD:1624291
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:13792537
RGD:1600115
G Stk36 serine/threonine kinase 36 JBrowse link 9 81,880,175 81,908,014 RGD:1624291
G Tedc1 tubulin epsilon and delta complex 1 JBrowse link 6 137,967,119 137,976,324 RGD:1600115
RGD:1624291
G Tedc2 tubulin epsilon and delta complex 2 JBrowse link 10 13,586,852 13,591,938 RGD:1600115
RGD:1624291
G Ttc23 tetratricopeptide repeat domain 23 JBrowse link 1 128,604,324 128,687,900 RGD:1600115
RGD:1624291
G Tubd1 tubulin, delta 1 JBrowse link 10 73,865,828 73,886,976 RGD:1624291
G Txndc15 thioredoxin domain containing 15 JBrowse link 17 9,429,171 9,441,628 RGD:1600115
RGD:1624291
G Ulk3 unc-51 like kinase 3 JBrowse link 8 62,368,548 62,375,229 RGD:1600115
RGD:1624291
G Wnt9a Wnt family member 9A JBrowse link 10 45,659,045 45,686,103 RGD:1624291
positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gorab golgin, RAB6-interacting JBrowse link 13 81,682,207 81,698,827 RGD:1624291
regulation of smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actrt1 actin-related protein T1 JBrowse link X 133,227,699 133,229,052 RGD:1600115
RGD:1624291
G Arl6 ADP-ribosylation factor like GTPase 6 JBrowse link 11 42,858,476 42,884,324 RGD:1624291
G C2cd3 C2 domain containing 3 centriole elongation regulator JBrowse link 1 165,382,279 165,480,088 RGD:1624291
G Fbxl17 F-box and leucine-rich repeat protein 17 JBrowse link 9 110,515,558 110,936,631 RGD:1624291
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Fuz fuzzy planar cell polarity protein JBrowse link 1 100,891,832 100,896,811 RGD:1600115
RGD:1624291
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:1624291
G Ift140 intraflagellar transport 140 JBrowse link 10 14,373,668 14,461,509 RGD:1624291
G Ift172 intraflagellar transport 172 JBrowse link 6 26,390,686 26,485,459 RGD:1624291
G Ift81 intraflagellar transport 81 JBrowse link 12 39,420,161 39,507,412 RGD:1600115
RGD:1624291
G Intu inturned planar cell polarity protein JBrowse link 2 127,589,325 127,611,705 RGD:1600115
RGD:1624291
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1624291
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1600115
G Rab23 RAB23, member RAS oncogene family JBrowse link 9 38,469,784 38,496,185 RGD:1624291
G Rora RAR-related orphan receptor A JBrowse link 8 75,515,886 75,616,477 RGD:1624291
G Rpgrip1l Rpgrip1-like JBrowse link 19 17,115,266 17,208,055 RGD:1624291
G Tctn1 tectonic family member 1 JBrowse link 12 39,790,948 39,828,215 RGD:1624291
G Ttbk2 tau tubulin kinase 2 JBrowse link 3 112,677,932 112,789,615 RGD:1624291
G Ttc21b tetratricopeptide repeat domain 21B JBrowse link 3 52,286,794 52,361,060 RGD:1624291
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
G Wdr11 WD repeat domain 11 JBrowse link 1 202,770,810 202,816,336 RGD:1624291
G Zic1 Zic family member 1 JBrowse link 8 98,733,715 98,738,960 RGD:1624291
regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1624291
RGD:1600115
signal transduction downstream of smoothened term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ift122 intraflagellar transport 122 JBrowse link 4 147,756,574 147,826,983 RGD:1624291
smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Ift122 intraflagellar transport 122 JBrowse link 4 147,756,574 147,826,983 RGD:1624291
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
G Tbc1d32 TBC1 domain family, member 32 JBrowse link 20 37,463,879 37,701,268 RGD:1624291
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
G Wdr19 WD repeat domain 19 JBrowse link 14 44,705,012 44,767,120 RGD:1624291
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1600115
RGD:1624291
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    signaling 7456
      signal transduction 6872
        cell surface receptor signaling pathway 2674
          smoothened signaling pathway 155
            ciliary receptor clustering involved in smoothened signaling pathway 4
            mesenchymal smoothened signaling pathway involved in prostate gland development 1
            negative regulation of smoothened signaling pathway + 33
            positive regulation of smoothened signaling pathway + 43
            regulation of smoothened signaling pathway + 90
            signal transduction downstream of smoothened + 4
            smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 14
            smoothened signaling pathway involved in growth plate cartilage chondrocyte development 0
            smoothened signaling pathway involved in lung development 0
            smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 4
            smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
            smoothened signaling pathway involved in ventral spinal cord patterning + 8
Path 2
Term Annotations click to browse term
  biological_process 19336
    biological regulation 13340
      regulation of biological process 12655
        regulation of cellular process 11994
          signal transduction 6872
            cell surface receptor signaling pathway 2674
              smoothened signaling pathway 155
                ciliary receptor clustering involved in smoothened signaling pathway 4
                mesenchymal smoothened signaling pathway involved in prostate gland development 1
                negative regulation of smoothened signaling pathway + 33
                positive regulation of smoothened signaling pathway + 43
                regulation of smoothened signaling pathway + 90
                signal transduction downstream of smoothened + 4
                smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 14
                smoothened signaling pathway involved in growth plate cartilage chondrocyte development 0
                smoothened signaling pathway involved in lung development 0
                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 4
                smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
                smoothened signaling pathway involved in ventral spinal cord patterning + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.