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ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway
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Accession:GO:0007224 term browser browse the term
Definition:A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
Synonyms:exact_synonym: hedgehog signaling pathway;   smoothened signalling pathway
 narrow_synonym: Sonic hedgehog signaling pathway;   hh signaling pathway;   hh signalling pathway
 related_synonym: Shh signaling pathway
 xref: MIPS_funcat:30.05.02.16;   Wikipedia:Hedgehog_signaling_pathway


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smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARL13B ADP ribosylation factor like GTPase 13B JBrowse link 3 93,980,139 94,055,678 RGD:2290271
G ARL3 ADP ribosylation factor like GTPase 3 JBrowse link 10 102,673,731 102,714,397 RGD:2290271
G B9D1 B9 domain containing 1 JBrowse link 17 19,334,695 19,377,913 RGD:2290271
G BBS7 Bardet-Biedl syndrome 7 JBrowse link 4 121,824,329 121,870,497 RGD:2290271
G BMP4 bone morphogenetic protein 4 JBrowse link 14 53,949,736 53,956,891 RGD:2290271
G BOC BOC cell adhesion associated, oncogene regulated JBrowse link 3 113,211,003 113,287,463 RGD:2290271
G CC2D2A coiled-coil and C2 domain containing 2A JBrowse link 4 15,468,660 15,601,971 RGD:2290271
G CDON cell adhesion associated, oncogene regulated JBrowse link 11 125,956,813 126,063,335 RGD:2290271
G CENPJ centromere protein J JBrowse link 13 24,882,279 24,922,889 RGD:2290271
G DHH desert hedgehog signaling molecule JBrowse link 12 49,086,656 49,094,801 RGD:2290271
G DISP2 dispatched RND transporter family member 2 JBrowse link 15 40,354,359 40,378,621 RGD:2290271
G DISP3 dispatched RND transporter family member 3 JBrowse link 1 11,479,155 11,537,583 RGD:2290271
G DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 JBrowse link 12 67,648,745 67,665,406 RGD:2290271
G DZIP1 DAZ interacting zinc finger protein 1 JBrowse link 13 95,578,202 95,644,706 RGD:2290271
G DZIP1L DAZ interacting zinc finger protein 1 like JBrowse link 3 138,061,990 138,115,862 RGD:2290271
G EVC EvC ciliary complex subunit 1 JBrowse link 4 5,711,199 5,829,043 RGD:2290271
G EVC2 EvC ciliary complex subunit 2 JBrowse link 4 5,562,408 5,709,548 RGD:2290271
G FKBP8 FKBP prolyl isomerase 8 JBrowse link 19 18,531,763 18,543,573 RGD:2290271
G FOXF1 forkhead box F1 JBrowse link 16 86,510,527 86,515,422 RGD:2290271
G GLI1 GLI family zinc finger 1 JBrowse link 12 57,459,785 57,472,451 RGD:2290271
G GLI2 GLI family zinc finger 2 JBrowse link 2 120,735,868 120,992,653 RGD:2290271
G GLI3 GLI family zinc finger 3 JBrowse link 7 41,960,949 42,237,209 RGD:2290271
G GPC2 glypican 2 JBrowse link 7 100,169,606 100,177,381 RGD:2290271
G HES1 hes family bHLH transcription factor 1 JBrowse link 3 194,136,148 194,138,732 RGD:2290271
G HES5 hes family bHLH transcription factor 5 JBrowse link 1 2,528,745 2,530,554 RGD:2290271
G HHAT hedgehog acyltransferase JBrowse link 1 210,327,873 210,676,298 RGD:2290271
G HIPK1 homeodomain interacting protein kinase 1 JBrowse link 1 113,929,324 113,977,869 RGD:2290271
G HIPK2 homeodomain interacting protein kinase 2 JBrowse link 7 139,561,570 139,777,998 RGD:2290271
G HSPB11 heat shock protein family B (small) member 11 JBrowse link 1 53,921,561 53,946,308 RGD:2290271
G IFT172 intraflagellar transport 172 JBrowse link 2 27,444,373 27,489,819 RGD:2290271
G IFT20 intraflagellar transport 20 JBrowse link 17 28,328,325 28,335,489 RGD:2290271
G IFT27 intraflagellar transport 27 JBrowse link 22 36,758,208 36,776,119 RGD:2290271
G IFT46 intraflagellar transport 46 JBrowse link 11 118,544,528 118,576,456 RGD:2290271
G IFT52 intraflagellar transport 52 JBrowse link 20 43,590,937 43,647,299 RGD:2290271
G IFT57 intraflagellar transport 57 JBrowse link 3 108,160,812 108,222,424 RGD:2290271
G IFT80 intraflagellar transport 80 JBrowse link 3 160,256,986 160,399,225 RGD:2290271
G IHH Indian hedgehog signaling molecule JBrowse link 2 219,054,424 219,060,921 RGD:2290271
G IQUB IQ motif and ubiquitin domain containing JBrowse link 7 123,452,181 123,534,664 RGD:2290271
G KIAA0586 KIAA0586 JBrowse link 14 58,427,385 58,551,297 RGD:2290271
G KIF3A kinesin family member 3A JBrowse link 5 132,688,808 132,737,563 RGD:2290271
G MAP3K10 mitogen-activated protein kinase kinase kinase 10 JBrowse link 19 40,191,426 40,215,575 RGD:2290271
G NKX2-2 NK2 homeobox 2 JBrowse link 20 21,511,010 21,514,064 RGD:2290271
G NKX6-1 NK6 homeobox 1 JBrowse link 4 84,493,283 84,498,234 RGD:2290271
G NSDHL NAD(P) dependent steroid dehydrogenase-like JBrowse link X 152,830,967 152,869,729 RGD:2290271
G PAX6 paired box 6 JBrowse link 11 31,784,792 31,817,961 RGD:2290271
G PDX1 pancreatic and duodenal homeobox 1 JBrowse link 13 27,919,982 27,926,313 RGD:2290271
G PKD2L1 polycystin 2 like 1, transient receptor potential cation channel JBrowse link 10 100,288,145 100,347,030 RGD:2290271
G PTCH1 patched 1 JBrowse link 9 95,442,980 95,517,057 RGD:2290271
G PTCH2 patched 2 JBrowse link 1 44,819,844 44,843,253 RGD:2290271
G PTCHD1 patched domain containing 1 JBrowse link X 23,334,369 23,404,374 RGD:2290271
G PTPDC1 protein tyrosine phosphatase domain containing 1 JBrowse link 9 94,029,031 94,109,856 RGD:2290271
G RO60 Ro60, Y RNA binding protein JBrowse link 1 193,059,454 193,091,777 RGD:2290271
G ROR2 receptor tyrosine kinase like orphan receptor 2 JBrowse link 9 91,722,598 91,950,228 RGD:2290271
G SEPTIN2 septin 2 JBrowse link 2 241,315,187 241,354,027 RGD:2290271
G SHH sonic hedgehog signaling molecule JBrowse link 7 155,799,980 155,812,463 RGD:2290271
G SMO smoothened, frizzled class receptor JBrowse link 7 129,188,633 129,213,548 RGD:2290271
G STIL STIL centriolar assembly protein JBrowse link 1 47,250,139 47,314,787 RGD:2290271
G TCTN2 tectonic family member 2 JBrowse link 12 123,671,108 123,708,405 RGD:2290271
G TCTN3 tectonic family member 3 JBrowse link 10 95,663,396 95,694,143 RGD:2290271
G TGFBR2 transforming growth factor beta receptor 2 JBrowse link 3 30,606,472 30,694,142 RGD:2290271
G TMEM17 transmembrane protein 17 JBrowse link 2 62,452,778 62,511,894 RGD:2290271
G TMEM231 transmembrane protein 231 JBrowse link 16 75,536,741 75,556,286 RGD:2290271
G TTBK2 tau tubulin kinase 2 JBrowse link 15 42,738,730 42,920,995 RGD:2290271
G TTC21B tetratricopeptide repeat domain 21B JBrowse link 2 165,873,362 165,953,781 RGD:2290271
G TTC26 tetratricopeptide repeat domain 26 JBrowse link 7 139,133,744 139,191,986 RGD:2290271
G WDPCP WD repeat containing planar cell polarity effector JBrowse link 2 63,119,559 63,588,733 RGD:2290271
G WNT10B Wnt family member 10B JBrowse link 12 48,965,340 48,979,587 RGD:2290271
ciliary receptor clustering involved in smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFT122 intraflagellar transport 122 JBrowse link 3 129,440,036 129,520,507 RGD:2290271
G SSNA1 SS nuclear autoantigen 1 JBrowse link 9 137,188,676 137,190,366 RGD:2290271
G WDR19 WD repeat domain 19 JBrowse link 4 39,182,473 39,285,810 RGD:2290271
mesenchymal smoothened signaling pathway involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SHH sonic hedgehog signaling molecule JBrowse link 7 155,799,980 155,812,463 RGD:2290271
negative regulation of hh target transcription factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 6 131,808,020 131,895,155 RGD:2290271
negative regulation of smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 10 101,353,808 101,557,321 RGD:2290271
G CD3E CD3e molecule JBrowse link 11 118,304,730 118,316,173 RGD:2290271
G GLI2 GLI family zinc finger 2 JBrowse link 2 120,735,868 120,992,653 RGD:2290271
G GLI3 GLI family zinc finger 3 JBrowse link 7 41,960,949 42,237,209 RGD:2290271
G GLIS2 GLIS family zinc finger 2 JBrowse link 16 4,314,761 4,339,597 RGD:2290271
G GPC3 glypican 3 JBrowse link X 133,535,745 133,985,616 RGD:2290271
G GPR37L1 G protein-coupled receptor 37 like 1 JBrowse link 1 202,118,669 202,133,592 RGD:2290271
G HHIP hedgehog interacting protein JBrowse link 4 144,646,154 144,745,271 RGD:2290271
G IFT122 intraflagellar transport 122 JBrowse link 3 129,440,036 129,520,507 RGD:2290271
G IFT172 intraflagellar transport 172 JBrowse link 2 27,444,373 27,489,819 RGD:2290271
G KCTD21 potassium channel tetramerization domain containing 21 JBrowse link 11 78,171,243 78,188,854 RGD:2290271
G KCTD6 potassium channel tetramerization domain containing 6 JBrowse link 3 58,492,096 58,502,360 RGD:2290271
G KIF7 kinesin family member 7 JBrowse link 15 89,627,977 89,663,086 RGD:2290271
G MEGF8 multiple EGF like domains 8 JBrowse link 19 42,325,635 42,378,765 RGD:2290271
G MGRN1 mahogunin ring finger 1 JBrowse link 16 4,624,824 4,690,974 RGD:2290271
G MOSMO modulator of smoothened JBrowse link 16 22,008,111 22,084,654 RGD:2290271
G PTCH1 patched 1 JBrowse link 9 95,442,980 95,517,057 RGD:2290271
G PTCH2 patched 2 JBrowse link 1 44,819,844 44,843,253 RGD:2290271
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,303,747 48,481,890 RGD:2290271
G RUNX2 RUNX family transcription factor 2 JBrowse link 6 45,328,317 45,551,082 RGD:2290271
G SALL3 spalt like transcription factor 3 JBrowse link 18 78,980,275 78,998,969 RGD:2290271
G SERPINE2 serpin family E member 2 JBrowse link 2 223,975,045 224,039,319 RGD:2290271
G SUFU SUFU negative regulator of hedgehog signaling JBrowse link 10 102,502,801 102,633,535 RGD:2290271
G TULP3 TUB like protein 3 JBrowse link 12 2,890,891 2,941,138 RGD:2290271
G ULK3 unc-51 like kinase 3 JBrowse link 15 74,836,118 74,843,166 RGD:2290271
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GPR161 G protein-coupled receptor 161 JBrowse link 1 168,079,542 168,137,667 RGD:2290271
G PRKACA protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 14,091,688 14,117,762 RGD:2290271
G PRKACB protein kinase cAMP-activated catalytic subunit beta JBrowse link 1 84,077,975 84,238,498 RGD:2290271
G SUFU SUFU negative regulator of hedgehog signaling JBrowse link 10 102,502,801 102,633,535 RGD:2290271
G TRAF3IP1 TRAF3 interacting protein 1 JBrowse link 2 238,320,489 238,400,900 RGD:2290271
G TULP3 TUB like protein 3 JBrowse link 12 2,890,891 2,941,138 RGD:2290271
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFT122 intraflagellar transport 122 JBrowse link 3 129,440,036 129,520,507 RGD:2290271
G RFX4 regulatory factor X4 JBrowse link 12 106,583,004 106,762,803 RGD:2290271
G RFX8 RFX family member 8, lacking RFX DNA binding domain JBrowse link 2 101,397,344 101,475,179 RGD:2290271
G TULP3 TUB like protein 3 JBrowse link 12 2,890,891 2,941,138 RGD:2290271
patched ligand maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DISP1 dispatched RND transporter family member 1 JBrowse link 1 222,814,514 223,005,995 RGD:2290271
positive regulation of hh target transcription factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SHH sonic hedgehog signaling molecule JBrowse link 7 155,799,980 155,812,463 RGD:2290271
G SMO smoothened, frizzled class receptor JBrowse link 7 129,188,633 129,213,548 RGD:2290271
G STK36 serine/threonine kinase 36 JBrowse link 2 218,672,049 218,702,717 RGD:2290271
positive regulation of smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARMC9 armadillo repeat containing 9 JBrowse link 2 231,198,628 231,394,991 RGD:2290271
G CHSY1 chondroitin sulfate synthase 1 JBrowse link 15 101,175,727 101,252,048 RGD:2290271
G CIBAR1 CBY1 interacting BAR domain containing 1 JBrowse link 8 93,700,550 93,731,527 RGD:2290271
G CTNNA1 catenin alpha 1 JBrowse link 5 138,753,386 138,935,034 RGD:2290271
G DCDC2 doublecortin domain containing 2 JBrowse link 6 24,171,755 24,383,292 RGD:2290271
G DLG5 discs large MAGUK scaffold protein 5 JBrowse link 10 77,790,787 77,926,755 RGD:2290271
G DYNC2H1 dynein cytoplasmic 2 heavy chain 1 JBrowse link 11 103,109,426 103,479,863 RGD:2290271
G EVC EvC ciliary complex subunit 1 JBrowse link 4 5,711,199 5,829,043 RGD:2290271
G FGF9 fibroblast growth factor 9 JBrowse link 13 21,671,073 21,704,501 RGD:2290271
G FOXA1 forkhead box A1 JBrowse link 14 37,589,552 37,595,249 RGD:2290271
G GAS8 growth arrest specific 8 JBrowse link 16 90,019,629 90,044,971 RGD:2290271
G GLI1 GLI family zinc finger 1 JBrowse link 12 57,459,785 57,472,451 RGD:2290271
G GPC3 glypican 3 JBrowse link X 133,535,745 133,985,616 RGD:2290271
G IFT172 intraflagellar transport 172 JBrowse link 2 27,444,373 27,489,819 RGD:2290271
G IHH Indian hedgehog signaling molecule JBrowse link 2 219,054,424 219,060,921 RGD:2290271
G INTU inturned planar cell polarity protein JBrowse link 4 127,623,271 127,726,737 RGD:2290271
G KIF7 kinesin family member 7 JBrowse link 15 89,627,977 89,663,086 RGD:2290271
G NDST1 N-deacetylase and N-sulfotransferase 1 JBrowse link 5 150,497,779 150,558,211 RGD:2290271
G PDCL phosducin like JBrowse link 9 122,818,097 122,828,588 RGD:2290271
G POR cytochrome p450 oxidoreductase JBrowse link 7 75,915,155 75,986,855 RGD:2290271
G PRRX1 paired related homeobox 1 JBrowse link 1 170,662,728 170,739,421 RGD:2290271
G RAB34 RAB34, member RAS oncogene family JBrowse link 17 28,714,281 28,718,440 RGD:2290271
G SCUBE1 signal peptide, CUB domain and EGF like domain containing 1 JBrowse link 22 43,197,280 43,343,372 RGD:2290271
G SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 JBrowse link 6 35,213,956 35,253,079 RGD:2290271
G SFRP1 secreted frizzled related protein 1 JBrowse link 8 41,261,962 41,309,473 RGD:2290271
G SHH sonic hedgehog signaling molecule JBrowse link 7 155,799,980 155,812,463 RGD:2290271
G SHOX2 short stature homeobox 2 JBrowse link 3 158,095,905 158,106,420 RGD:2290271
G SKOR2 SKI family transcriptional corepressor 2 JBrowse link 18 47,206,169 47,251,660 RGD:2290271
G SMO smoothened, frizzled class receptor JBrowse link 7 129,188,633 129,213,548 RGD:2290271
G STK36 serine/threonine kinase 36 JBrowse link 2 218,672,049 218,702,717 RGD:2290271
G TEDC1 tubulin epsilon and delta complex 1 JBrowse link 14 105,489,855 105,499,248 RGD:2290271
G TEDC2 tubulin epsilon and delta complex 2 JBrowse link 16 2,460,109 2,464,963 RGD:2290271
G TTC23 tetratricopeptide repeat domain 23 JBrowse link 15 99,136,323 99,251,226 RGD:2290271
G TUBD1 tubulin delta 1 JBrowse link 17 59,859,467 59,892,948 RGD:2290271
G TXNDC15 thioredoxin domain containing 15 JBrowse link 5 134,873,770 134,901,635 RGD:2290271
G ULK3 unc-51 like kinase 3 JBrowse link 15 74,836,118 74,843,166 RGD:2290271
G WNT9A Wnt family member 9A JBrowse link 1 227,918,656 227,947,932 RGD:2290271
positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GORAB golgin, RAB6 interacting JBrowse link 1 170,532,134 170,553,834 RGD:2290271
regulation of smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTRT1 actin related protein T1 JBrowse link X 128,050,962 128,052,403 RGD:2290271
G ARL6 ADP ribosylation factor like GTPase 6 JBrowse link 3 97,762,581 97,812,585 RGD:2290271
G C2CD3 C2 domain containing 3 centriole elongation regulator JBrowse link 11 74,012,578 74,171,210 RGD:2290271
G CREBBP CREB binding protein JBrowse link 16 3,725,054 3,880,727 RGD:2290271
G FBXL17 F-box and leucine rich repeat protein 17 JBrowse link 5 107,859,035 108,382,098 RGD:2290271
G FGF10 fibroblast growth factor 10 JBrowse link 5 44,300,247 44,389,706 RGD:2290271
G FGFR2 fibroblast growth factor receptor 2 JBrowse link 10 121,478,330 121,598,458 RGD:2290271
G FUZ fuzzy planar cell polarity protein JBrowse link 19 49,806,866 49,817,376 RGD:2290271
G GAS1 growth arrest specific 1 JBrowse link 9 86,944,362 86,947,506 RGD:2290271
G GLI1 GLI family zinc finger 1 JBrowse link 12 57,459,785 57,472,451 RGD:2290271
G IFT140 intraflagellar transport 140 JBrowse link 16 1,510,427 1,612,072 RGD:2290271
G IFT81 intraflagellar transport 81 JBrowse link 12 110,124,335 110,218,793 RGD:2290271
G INTU inturned planar cell polarity protein JBrowse link 4 127,623,271 127,726,737 RGD:2290271
G OTX2 orthodenticle homeobox 2 JBrowse link 14 56,799,905 56,810,479 RGD:2290271
G PTCH1 patched 1 JBrowse link 9 95,442,980 95,517,057 RGD:2290271
G RORA RAR related orphan receptor A JBrowse link 15 60,488,284 61,229,302 RGD:2290271
G RPGRIP1L RPGRIP1 like JBrowse link 16 53,598,153 53,703,938 RGD:2290271
G TCTN1 tectonic family member 1 JBrowse link 12 110,614,068 110,649,430 RGD:2290271
G TTC21B tetratricopeptide repeat domain 21B JBrowse link 2 165,873,362 165,953,781 RGD:2290271
G WDR11 WD repeat domain 11 JBrowse link 10 120,851,313 120,909,525 RGD:2290271
G ZIC1 Zic family member 1 JBrowse link 3 147,409,365 147,416,719 RGD:2290271
regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MKS1 MKS transition zone complex subunit 1 JBrowse link 17 58,205,436 58,219,605 RGD:2290271
signal transduction downstream of smoothened term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFT122 intraflagellar transport 122 JBrowse link 3 129,440,036 129,520,507 RGD:2290271
smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GLI2 GLI family zinc finger 2 JBrowse link 2 120,735,868 120,992,653 RGD:2290271
G GLI3 GLI family zinc finger 3 JBrowse link 7 41,960,949 42,237,209 RGD:2290271
G IFT122 intraflagellar transport 122 JBrowse link 3 129,440,036 129,520,507 RGD:2290271
G PTCH1 patched 1 JBrowse link 9 95,442,980 95,517,057 RGD:2290271
G TBC1D32 TBC1 domain family member 32 JBrowse link 6 121,079,494 121,335,384 RGD:2290271
G TULP3 TUB like protein 3 JBrowse link 12 2,890,891 2,941,138 RGD:2290271
G WDR19 WD repeat domain 19 JBrowse link 4 39,182,473 39,285,810 RGD:2290271
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GLI1 GLI family zinc finger 1 JBrowse link 12 57,459,785 57,472,451 RGD:2290271
G GLI2 GLI family zinc finger 2 JBrowse link 2 120,735,868 120,992,653 RGD:2290271
G SHH sonic hedgehog signaling molecule JBrowse link 7 155,799,980 155,812,463 RGD:2290271
G SMO smoothened, frizzled class receptor JBrowse link 7 129,188,633 129,213,548 RGD:2290271
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MKS1 MKS transition zone complex subunit 1 JBrowse link 17 58,205,436 58,219,605 RGD:2290271
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GLI2 GLI family zinc finger 2 JBrowse link 2 120,735,868 120,992,653 RGD:2290271
G GLI3 GLI family zinc finger 3 JBrowse link 7 41,960,949 42,237,209 RGD:2290271
G SUFU SUFU negative regulator of hedgehog signaling JBrowse link 10 102,502,801 102,633,535 RGD:2290271
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GLI2 GLI family zinc finger 2 JBrowse link 2 120,735,868 120,992,653 RGD:2290271
G GLI3 GLI family zinc finger 3 JBrowse link 7 41,960,949 42,237,209 RGD:2290271
G SUFU SUFU negative regulator of hedgehog signaling JBrowse link 10 102,502,801 102,633,535 RGD:2290271
smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SMO smoothened, frizzled class receptor JBrowse link 7 129,188,633 129,213,548 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17988
    signaling 6838
      signal transduction 6305
        cell surface receptor signaling pathway 3207
          smoothened signaling pathway 145
            ciliary receptor clustering involved in smoothened signaling pathway 3
            mesenchymal smoothened signaling pathway involved in prostate gland development 1
            negative regulation of smoothened signaling pathway + 32
            positive regulation of smoothened signaling pathway + 39
            regulation of smoothened signaling pathway + 86
            signal transduction downstream of smoothened + 4
            smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 14
            smoothened signaling pathway involved in growth plate cartilage chondrocyte development 0
            smoothened signaling pathway involved in lung development 0
            smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 4
            smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
            smoothened signaling pathway involved in ventral spinal cord patterning + 8
Path 2
Term Annotations click to browse term
  biological_process 17988
    biological regulation 12615
      regulation of biological process 11925
        regulation of cellular process 11208
          signal transduction 6305
            cell surface receptor signaling pathway 3207
              smoothened signaling pathway 145
                ciliary receptor clustering involved in smoothened signaling pathway 3
                mesenchymal smoothened signaling pathway involved in prostate gland development 1
                negative regulation of smoothened signaling pathway + 32
                positive regulation of smoothened signaling pathway + 39
                regulation of smoothened signaling pathway + 86
                signal transduction downstream of smoothened + 4
                smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 14
                smoothened signaling pathway involved in growth plate cartilage chondrocyte development 0
                smoothened signaling pathway involved in lung development 0
                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 4
                smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
                smoothened signaling pathway involved in ventral spinal cord patterning + 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.