Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:patched ligand maturation
go back to main search page
Accession:GO:0007225 term browser browse the term
Definition:The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.
Synonyms:exact_synonym: hh protein processing
 narrow_synonym: Hedgehog protein processing
 related_synonym: patched ligand processing


show annotations for term's descendants       view all columns           Sort by:
 
patched ligand maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DISP1 dispatched RND transporter family member 1 JBrowse link 1 203,501,711 203,692,218 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15758
    metabolic process 10722
      hormone metabolic process 222
        peptide hormone processing 30
          patched ligand maturation 1
Path 2
Term Annotations click to browse term
  biological_process 15758
    metabolic process 10722
      organic substance metabolic process 10201
        macromolecule metabolic process 8835
          protein metabolic process 5500
            proteolysis 1689
              protein processing 206
                signaling receptor ligand precursor processing 31
                  peptide hormone processing 30
                    patched ligand maturation 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.