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ONTOLOGY REPORT - ANNOTATIONS


Term:patched ligand maturation
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Accession:GO:0007225 term browser browse the term
Definition:The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.
Synonyms:exact_synonym: hh protein processing
 narrow_synonym: Hedgehog protein processing
 related_synonym: patched ligand processing


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patched ligand maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Disp1 dispatched RND transporter family member 1 JBrowse link NW_004955520 1,591,831 1,711,871 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14616
    metabolic process 10124
      hormone metabolic process 201
        peptide hormone processing 29
          patched ligand maturation 1
Path 2
Term Annotations click to browse term
  biological_process 14616
    metabolic process 10124
      organic substance metabolic process 9625
        macromolecule metabolic process 8332
          protein metabolic process 5281
            proteolysis 1588
              protein processing 198
                signaling receptor ligand precursor processing 29
                  peptide hormone processing 29
                    patched ligand maturation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.