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ONTOLOGY REPORT - ANNOTATIONS


Term:patched ligand maturation
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Accession:GO:0007225 term browser browse the term
Definition:The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.
Synonyms:exact_synonym: hh protein processing
 narrow_synonym: Hedgehog protein processing
 related_synonym: patched ligand processing


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patched ligand maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Disp1 dispatched RND transporter family member 1 JBrowse link 1 183,086,264 183,221,537 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23162
    metabolic process 10900
      hormone metabolic process 229
        peptide hormone processing 19
          patched ligand maturation 1
Path 2
Term Annotations click to browse term
  biological_process 23162
    metabolic process 10900
      organic substance metabolic process 10349
        macromolecule metabolic process 8877
          protein metabolic process 5314
            proteolysis 1704
              protein processing 225
                signaling receptor ligand precursor processing 21
                  peptide hormone processing 19
                    patched ligand maturation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.