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ONTOLOGY REPORT - ANNOTATIONS


Term:patched ligand maturation
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Accession:GO:0007225 term browser browse the term
Definition:The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.
Synonyms:exact_synonym: hh protein processing
 narrow_synonym: Hedgehog protein processing
 related_synonym: patched ligand processing


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patched ligand maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DISP1 dispatched RND transporter family member 1 JBrowse link 10 11,526,353 11,709,888 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15162
    metabolic process 9321
      hormone metabolic process 149
        peptide hormone processing 14
          patched ligand maturation 1
Path 2
Term Annotations click to browse term
  biological_process 15162
    metabolic process 9321
      organic substance metabolic process 8758
        macromolecule metabolic process 7560
          protein metabolic process 4514
            proteolysis 1415
              protein processing 150
                signaling receptor ligand precursor processing 14
                  peptide hormone processing 14
                    patched ligand maturation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.