ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasmic sequestering of NF-kappaB
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Accession:GO:0007253 term browser browse the term
Definition:The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
Synonyms:exact_synonym: cytoplasmic NF-kappaB retention;   cytoplasmic NF-kappaB sequestration;   cytoplasmic NF-kappaB storage;   cytoplasmic retention of NF-kappaB;   cytoplasmic sequestration of NF-kappaB;   cytoplasmic storage of NF-kappaB;   maintenance of NF-kappaB location in cytoplasm


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cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccdc22 coiled-coil domain containing 22 JBrowse link X 15,742,978 15,754,925 RGD:1624291
RGD:1600115
G Faf1 Fas associated factor 1 JBrowse link 5 129,370,767 129,738,393 RGD:1600115
RGD:1624291
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:2298880
RGD:1624291
RGD:2298917
RGD:2298882
RGD:2298908
G Nfkbib NFKB inhibitor beta JBrowse link 1 86,941,073 86,948,845 RGD:2298908
RGD:2298917
G Psmd10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 112,323,188 112,328,642 RGD:1624291
RGD:1600115
G Tmsb4x thymosin beta 4, X-linked JBrowse link X 28,593,405 28,617,267 RGD:1624291

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Term Annotations click to browse term
  biological_process 17926
    negative regulation of biological process 5362
      negative regulation of DNA-binding transcription factor activity 165
        negative regulation of NF-kappaB transcription factor activity 81
          cytoplasmic sequestering of NF-kappaB 6
Path 2
Term Annotations click to browse term
  biological_process 17926
    metabolic process 10677
      cellular metabolic process 9772
        cellular aromatic compound metabolic process 5091
          nucleobase-containing compound metabolic process 4884
            nucleic acid metabolic process 4438
              RNA metabolic process 3968
                RNA biosynthetic process 3114
                  nucleic acid-templated transcription 3097
                    transcription, DNA-templated 3053
                      regulation of transcription, DNA-templated 2948
                        regulation of DNA-binding transcription factor activity 414
                          negative regulation of DNA-binding transcription factor activity 165
                            negative regulation of NF-kappaB transcription factor activity 81
                              cytoplasmic sequestering of NF-kappaB 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.