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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of JNKK activity
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Accession:GO:0007256 term browser browse the term
Definition:The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
Synonyms:exact_synonym: activation of JUN kinase kinase activity
 broad_synonym: positive regulation of JUNKK activity


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activation of JNKK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:1624291
RGD:1600115
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:2293488
G Map3k10 mitogen activated protein kinase kinase kinase 10 JBrowse link 1 84,473,178 84,491,689 RGD:1600115
G Map3k11 mitogen-activated protein kinase kinase kinase 11 JBrowse link 1 221,043,119 221,056,420 RGD:2298577
G Map3k12 mitogen activated protein kinase kinase kinase 12 JBrowse link 7 144,102,275 144,120,306 RGD:1600115
RGD:1624291
G Map3k13 mitogen-activated protein kinase kinase kinase 13 JBrowse link 11 82,744,391 82,938,357 RGD:1600115
RGD:1624291
G Map3k21 mitogen-activated protein kinase kinase kinase 21 JBrowse link 19 58,744,995 58,779,408 RGD:1600115
G Map3k9 mitogen-activated protein kinase kinase kinase 9 JBrowse link 6 105,455,461 105,518,974 RGD:1600115
G Mapkbp1 mitogen activated protein kinase binding protein 1 JBrowse link 3 111,767,126 111,817,103 RGD:1624291
G Nrk Nik related kinase JBrowse link X
X
109,940,439
110,065,199
110,036,361
110,089,124
RGD:1624291
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1600115
G Tnik TRAF2 and NCK interacting kinase JBrowse link 2 113,984,599 114,391,805 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    cellular process 17226
      signal transduction 6875
        signal transduction by protein phosphorylation 874
          MAPK cascade 854
            stress-activated MAPK cascade 273
              JNK cascade 210
                activation of JNKK activity 12
Path 2
Term Annotations click to browse term
  biological_process 19317
    metabolic process 11540
      organic substance metabolic process 10932
        macromolecule metabolic process 9412
          protein metabolic process 5975
            protein modification process 3864
              cellular protein modification process 3864
                protein phosphorylation 1961
                  signal transduction by protein phosphorylation 874
                    MAPK cascade 854
                      stress-activated MAPK cascade 273
                        regulation of stress-activated MAPK cascade 247
                          regulation of JNK cascade 195
                            positive regulation of JNK cascade 147
                              positive regulation of JUN kinase activity 77
                                activation of JNKK activity 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.