ONTOLOGY REPORT - ANNOTATIONS


Term:ensheathment of neurons
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Accession:GO:0007272 term browser browse the term
Definition:The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.
Synonyms:related_synonym: ionic insulation of neurons by glial cells


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axon ensheathment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MBP myelin basic protein JBrowse link 18 73,628,537 73,781,956 RGD:9068941
G PLP1 proteolipid protein 1 JBrowse link X 103,353,181 103,412,513 RGD:9068941
G POU3F1 POU class 3 homeobox 1 JBrowse link 1 38,650,713 38,666,721 RGD:9068941
G PPARD peroxisome proliferator activated receptor delta JBrowse link 6 36,003,914 36,081,132 RGD:9068941
G PRX periaxin JBrowse link 19 45,952,420 45,971,987 RGD:9068941
central nervous system myelin formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 50,897,004 50,915,849 RGD:9068941
G TENM4 teneurin transmembrane protein 4 JBrowse link 11 77,333,644 78,113,322 RGD:9068941
G TLR2 toll like receptor 2 JBrowse link 4 157,848,058 157,870,324 RGD:9068941
central nervous system myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLU clusterin JBrowse link 8 24,070,053 24,086,934 RGD:9068941
G FA2H fatty acid 2-hydroxylase JBrowse link 16 74,632,161 74,693,710 RGD:9068941
G MYRF myelin regulatory factor JBrowse link 11 60,412,780 60,448,579 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 10 88,093,539 88,197,902 RGD:9068941
central nervous system myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASPA aspartoacylase JBrowse link 17 3,522,858 3,546,279 RGD:9068941
G B4GALT5 beta-1,4-galactosyltransferase 5 JBrowse link 20 47,042,479 47,123,209 RGD:9068941
G B4GALT6 beta-1,4-galactosyltransferase 6 JBrowse link 18 28,438,302 28,500,940 RGD:9068941
G CNTN2 contactin 2 JBrowse link 1 184,931,902 184,966,482 RGD:9068941
G CNTNAP1 contactin associated protein 1 JBrowse link 17 14,842,577 14,858,896 RGD:9068941
G KCNJ10 potassium voltage-gated channel subfamily J member 10 JBrowse link 1 139,312,371 139,345,145 RGD:9068941
G MAG myelin associated glycoprotein JBrowse link 19 40,975,763 40,997,401 RGD:9068941
G MYRF myelin regulatory factor JBrowse link 11 60,412,780 60,448,579 RGD:9068941
G NCSTN nicastrin JBrowse link 1 139,618,229 139,633,911 RGD:9068941
G NKX6-2 NK6 homeobox 2 JBrowse link 10 133,682,456 133,683,445 RGD:9068941
G PLP1 proteolipid protein 1 JBrowse link X 103,353,181 103,412,513 RGD:9068941
G SOX10 SRY-box 10 JBrowse link 22 36,712,128 36,724,192 RGD:9068941
myelin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FIG4 FIG4 phosphoinositide 5-phosphatase JBrowse link 6 111,539,937 111,673,894 RGD:9068941
G GPC1 glypican 1 JBrowse link 2B 246,509,247 246,523,569 RGD:9068941
G ILK integrin linked kinase JBrowse link 11 6,418,717 6,425,788 RGD:9068941
G MPP5 membrane palmitoylated protein 5 JBrowse link 14 66,693,863 66,790,122 RGD:9068941
G MTMR2 myotubularin related protein 2 JBrowse link 11 94,367,038 94,457,138 RGD:9068941
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing JBrowse link 2B 213,628,997 213,721,299 RGD:9068941
G PMP22 peripheral myelin protein 22 JBrowse link 17 41,038,286 41,073,872 RGD:9068941
myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCD1 ATP binding cassette subfamily D member 1 JBrowse link X 153,162,412 153,182,424 RGD:9068941
G ABCD2 ATP binding cassette subfamily D member 2 JBrowse link 12 49,941,914 50,011,140 RGD:9068941
G CXCR4 C-X-C motif chemokine receptor 4 JBrowse link 2B 140,185,803 140,189,626 RGD:9068941
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 JBrowse link 18 10,973,596 11,210,416 RGD:9068941
myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACER3 alkaline ceramidase 3 JBrowse link 11 75,557,846 75,717,627 RGD:9068941
G ACSBG1 acyl-CoA synthetase bubblegum family member 1 JBrowse link 15 76,064,937 76,128,835 RGD:9068941
G ADGRG6 adhesion G protein-coupled receptor G6 JBrowse link 6 144,142,374 144,283,545 RGD:9068941
G AFG3L2 AFG3 like matrix AAA peptidase subunit 2 JBrowse link 18 17,062,250 17,109,400 RGD:9068941
G AMIGO1 adhesion molecule with Ig like domain 1 JBrowse link 1 111,110,361 111,115,714 RGD:9068941
G ATRN attractin JBrowse link 20 3,315,241 3,490,901 RGD:9068941
G BCAS1 breast carcinoma amplified sequence 1 JBrowse link 20 51,512,049 51,639,255 RGD:9068941
G CLDN5 claudin 5 JBrowse link 22 17,957,605 17,962,121 RGD:9068941
G CMTM8 CKLF like MARVEL transmembrane domain containing 8 JBrowse link 3 32,472,720 32,602,124 RGD:9068941
G EGR2 early growth response 2 JBrowse link 10 61,648,364 61,652,846 RGD:9068941
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta JBrowse link 14 74,399,056 74,405,770 RGD:9068941
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta JBrowse link 2A 27,456,571 27,462,706 RGD:9068941
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link 3 189,652,675 189,663,132 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 17 17,777,434 17,817,735 RGD:9068941
G FAM126A family with sequence similarity 126 member A JBrowse link 7 23,250,256 23,320,970 RGD:9068941
G GAL3ST1 galactose-3-O-sulfotransferase 1 JBrowse link 22 29,382,779 29,403,310 RGD:9068941
G GALC galactosylceramidase JBrowse link 14 87,905,098 87,965,769 RGD:9068941
G GJC3 gap junction protein gamma 3 JBrowse link 7 105,390,290 105,396,643 RGD:9068941
G HEXB hexosaminidase subunit beta JBrowse link 5 41,199,681 41,232,693 RGD:9068941
G JAM3 junctional adhesion molecule 3 JBrowse link 11 132,783,580 132,864,657 RGD:9068941
G KEL Kell metallo-endopeptidase (Kell blood group) JBrowse link 7 147,422,965 147,444,255 RGD:9068941
G KLK6 kallikrein related peptidase 6 JBrowse link 19 56,815,073 56,826,689 RGD:9068941
G LOC100977262 sodium channel protein type 2 subunit alpha JBrowse link 2B 169,873,992 170,026,392 RGD:9068941
G LPAR1 lysophosphatidic acid receptor 1 JBrowse link 9 110,179,600 110,344,103 RGD:9068941
G MAL mal, T cell differentiation protein JBrowse link 2A 95,930,298 95,956,573 RGD:9068941
G MAL2 mal, T cell differentiation protein 2 JBrowse link 8 118,413,406 118,452,972 RGD:9068941
G MALL mal, T cell differentiation protein like JBrowse link 2A 111,584,239 111,618,382 RGD:9068941
G MARVELD1 MARVEL domain containing 1 JBrowse link 10 97,824,913 97,829,502 RGD:9068941
G MBP myelin basic protein JBrowse link 18 73,628,537 73,781,956 RGD:9068941
G MPZ myelin protein zero JBrowse link 1 140,603,609 140,631,273 RGD:9068941
G MYO5A myosin VA JBrowse link 15 49,572,084 49,699,507 RGD:9068941
G NAB1 NGFI-A binding protein 1 JBrowse link 2B 195,868,102 195,911,497 RGD:9068941
G NAB2 NGFI-A binding protein 2 JBrowse link 12 32,085,031 32,091,498 RGD:9068941
G NFASC neurofascin JBrowse link 1 184,760,032 184,911,633 RGD:9068941
G OLIG2 oligodendrocyte transcription factor 2 JBrowse link 21 32,766,039 32,769,408 RGD:9068941
G PLLP plasmolipin JBrowse link 16 56,663,878 56,692,784 RGD:9068941
G PLP1 proteolipid protein 1 JBrowse link X 103,353,181 103,412,513 RGD:9068941
G PMP22 peripheral myelin protein 22 JBrowse link 17 41,038,286 41,073,872 RGD:9068941
G PSAP prosaposin JBrowse link 10 70,810,591 70,845,593 RGD:9068941
G SBF2 SET binding factor 2 JBrowse link 11 9,639,828 10,154,637 RGD:9068941
G SCN8A sodium voltage-gated channel alpha subunit 8 JBrowse link 12 37,725,471 38,057,190 RGD:9068941
G SERINC5 serine incorporator 5 JBrowse link 5 35,332,193 35,449,905 RGD:9068941
G SLC8A3 solute carrier family 8 member A3 JBrowse link 14 69,505,703 69,650,382 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 48,079,749 48,158,356 RGD:9068941
G TSC1 TSC complex subunit 1 JBrowse link 9 132,638,003 132,692,264 RGD:9068941
G TSPAN2 tetraspanin 2 JBrowse link 1 122,520,308 122,561,850 RGD:9068941
G XK X-linked Kx blood group JBrowse link X 37,846,539 37,892,348 RGD:9068941
G ZNF24 zinc finger protein 24 JBrowse link 18 32,139,846 32,152,397 RGD:9068941
G ZSCAN26 zinc finger and SCAN domain containing 26 JBrowse link 6 28,741,890 28,752,403 RGD:9068941
myelination in peripheral nervous system term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAM22 ADAM metallopeptidase domain 22 JBrowse link 7 93,578,988 93,846,903 RGD:9068941
G ADGRG6 adhesion G protein-coupled receptor G6 JBrowse link 6 144,142,374 144,283,545 RGD:9068941
G ARHGEF10 Rho guanine nucleotide exchange factor 10 JBrowse link 8 1,747,801 1,862,917 RGD:9068941
G CNTNAP1 contactin associated protein 1 JBrowse link 17 14,842,577 14,858,896 RGD:9068941
G DAG1 dystroglycan 1 JBrowse link 3 50,637,707 50,703,852 RGD:9068941
G ILK integrin linked kinase JBrowse link 11 6,418,717 6,425,788 RGD:9068941
G LGI4 leucine rich repeat LGI family member 4 JBrowse link 19 40,808,853 40,827,023 RGD:9068941
G MYOC myocilin JBrowse link 1 150,841,630 150,858,628 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 17 26,160,857 26,439,295 RGD:9068941
G NRG1 neuregulin 1 JBrowse link 8 29,049,787 29,267,531 RGD:9068941
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 9 84,022,677 84,378,307 RGD:9068941
G NTRK3 neurotrophic receptor tyrosine kinase 3 JBrowse link 15 85,776,819 86,157,209 RGD:9068941
G PARD3 par-3 family cell polarity regulator JBrowse link 10 34,807,707 35,393,308 RGD:9068941
G POU3F1 POU class 3 homeobox 1 JBrowse link 1 38,650,713 38,666,721 RGD:9068941
G POU3F2 POU class 3 homeobox 2 JBrowse link 6 100,558,883 100,564,670 RGD:9068941
G SIRT2 sirtuin 2 JBrowse link 19 44,533,965 44,554,838 RGD:9068941
G SKI SKI proto-oncogene JBrowse link 1 2,091,620 2,174,080 RGD:9068941
negative regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CTSC cathepsin C JBrowse link 11 86,890,010 86,933,847 RGD:9068941
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 2A 89,596,833 89,667,468 RGD:9068941
G FIG4 FIG4 phosphoinositide 5-phosphatase JBrowse link 6 111,539,937 111,673,894 RGD:9068941
G KLK8 kallikrein related peptidase 8 JBrowse link 19 56,832,643 56,858,549 RGD:9068941
G MTMR2 myotubularin related protein 2 JBrowse link 11 94,367,038 94,457,138 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 10 88,093,539 88,197,902 RGD:9068941
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 48,079,749 48,158,356 RGD:9068941
paranodal junction assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANK2 ankyrin 2 JBrowse link 4 115,760,071 116,446,170 RGD:9068941
G CD9 CD9 molecule JBrowse link 12 6,245,351 6,283,385 RGD:9068941
G CNTNAP1 contactin associated protein 1 JBrowse link 17 14,842,577 14,858,896 RGD:9068941
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 JBrowse link 18 10,973,596 11,210,416 RGD:9068941
G GNPAT glyceronephosphate O-acyltransferase JBrowse link 1 211,819,259 211,855,974 RGD:9068941
G NFASC neurofascin JBrowse link 1 184,760,032 184,911,633 RGD:9068941
G UGT8 UDP glycosyltransferase 8 JBrowse link 4 117,676,804 117,762,363 RGD:9068941
peripheral nervous system myelin formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,036,385 95,107,940 RGD:9068941
G NCMAP non-compact myelin associated protein JBrowse link 1 24,738,804 24,789,114 RGD:9068941
peripheral nervous system myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 105,211,645 105,236,756 RGD:9068941
G AKT2 AKT serine/threonine kinase 2 JBrowse link 19 45,791,043 45,846,359 RGD:9068941
G FA2H fatty acid 2-hydroxylase JBrowse link 16 74,632,161 74,693,710 RGD:9068941
G MPP5 membrane palmitoylated protein 5 JBrowse link 14 66,693,863 66,790,122 RGD:9068941
G NDRG1 N-myc downstream regulated 1 JBrowse link 8 132,866,245 132,926,514 RGD:9068941
G SH3TC2 SH3 domain and tetratricopeptide repeats 2 JBrowse link 5 150,439,183 150,498,467 RGD:9068941
G SOD1 superoxide dismutase 1 JBrowse link 21 31,411,702 31,419,432 RGD:9068941
positive regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CST7 cystatin F JBrowse link 20 25,237,251 25,248,364 RGD:9068941
G DAG1 dystroglycan 1 JBrowse link 3 50,637,707 50,703,852 RGD:9068941
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,036,385 95,107,940 RGD:9068941
G HGF hepatocyte growth factor JBrowse link 7 87,325,741 87,396,850 RGD:9068941
G MAG myelin associated glycoprotein JBrowse link 19 40,975,763 40,997,401 RGD:9068941
G MYRF myelin regulatory factor JBrowse link 11 60,412,780 60,448,579 RGD:9068941
G NCMAP non-compact myelin associated protein JBrowse link 1 24,738,804 24,789,114 RGD:9068941
G PARD3 par-3 family cell polarity regulator JBrowse link 10 34,807,707 35,393,308 RGD:9068941
G RNF10 ring finger protein 10 JBrowse link 12 121,491,665 121,533,548 RGD:9068941
G S100B S100 calcium binding protein B JBrowse link 21 46,197,750 46,203,953 RGD:9068941
G SLC25A12 solute carrier family 25 member 12 JBrowse link 2B 176,532,940 176,755,193 RGD:9068941
G SOX10 SRY-box 10 JBrowse link 22 36,712,128 36,724,192 RGD:9068941
G TENM4 teneurin transmembrane protein 4 JBrowse link 11 77,333,644 78,113,322 RGD:9068941
G WASF3 WASP family member 3 JBrowse link 13 26,250,171 26,328,553 RGD:9068941
regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 105,211,645 105,236,756 RGD:9068941
G CTNNB1 catenin beta 1 JBrowse link 3 41,372,368 41,414,030 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 3 204,319,410 204,586,232 RGD:9068941
G KIF14 kinesin family member 14 JBrowse link 1 180,462,381 180,528,302 RGD:9068941
G LGI4 leucine rich repeat LGI family member 4 JBrowse link 19 40,808,853 40,827,023 RGD:9068941
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,093,765 11,249,841 RGD:9068941
G NKX6-2 NK6 homeobox 2 JBrowse link 10 133,682,456 133,683,445 RGD:9068941
G RARA retinoic acid receptor alpha JBrowse link 17 17,156,923 17,205,451 RGD:9068941
G RARB retinoic acid receptor beta JBrowse link 3 25,660,850 25,830,372 RGD:9068941
G RARG retinoic acid receptor gamma JBrowse link 12 36,303,328 36,325,111 RGD:9068941
G SIRT2 sirtuin 2 JBrowse link 19 44,533,965 44,554,838 RGD:9068941
G TENM4 teneurin transmembrane protein 4 JBrowse link 11 77,333,644 78,113,322 RGD:9068941
G TG thyroglobulin JBrowse link 8 132,495,516 132,764,918 RGD:9068941
G TNFRSF1B TNF receptor superfamily member 1B JBrowse link 1 12,130,663 12,172,646 RGD:9068941
G TYMP thymidine phosphorylase JBrowse link 22 49,883,129 49,886,996 RGD:9068941
G ZPR1 ZPR1 zinc finger JBrowse link 11 115,547,951 115,557,883 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15676
    cellular process 14345
      ensheathment of neurons 124
        axon ensheathment + 124
        ensheathment of neuronal cell bodies 0
Path 2
Term Annotations click to browse term
  biological_process 15676
    developmental process 5899
      anatomical structure development 5536
        multicellular organism development 5080
          system development 4542
            nervous system development 2284
              ensheathment of neurons 124
                axon ensheathment + 124
                ensheathment of neuronal cell bodies 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.