ONTOLOGY REPORT - ANNOTATIONS


Term:ensheathment of neurons
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Accession:GO:0007272 term browser browse the term
Definition:The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.
Synonyms:related_synonym: ionic insulation of neurons by glial cells


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axon ensheathment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mbp myelin basic protein JBrowse link NW_004955402 60,324,060 60,448,926 RGD:9068941
G Plp1 proteolipid protein 1 JBrowse link NW_004955548 781,522 797,246 RGD:9068941
G Ppard peroxisome proliferator activated receptor delta JBrowse link NW_004955437 3,285,281 3,354,099 RGD:9068941
G Prx periaxin JBrowse link NW_004955578 852,789 873,319 RGD:9068941
central nervous system myelin formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link NW_004955555 2,355,005 2,369,599 RGD:9068941
G Tenm4 teneurin transmembrane protein 4 JBrowse link NW_004955414 12,649,128 13,364,523 RGD:9068941
G Tlr2 toll like receptor 2 JBrowse link NW_004955471 8,011,710 8,019,063 RGD:9068941
central nervous system myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clu clusterin JBrowse link NW_004955403 50,160,598 50,175,876 RGD:9068941
G Fa2h fatty acid 2-hydroxylase JBrowse link NW_004955484 2,726,496 2,775,763 RGD:9068941
G Myrf myelin regulatory factor JBrowse link NW_004955511 5,927,103 5,949,289 RGD:9068941
G Pten phosphatase and tensin homolog JBrowse link NW_004955425 5,007,811 5,091,829 RGD:9068941
central nervous system myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspa aspartoacylase JBrowse link NW_004955467 13,277,014 13,332,658 RGD:9068941
G B4galt5 beta-1,4-galactosyltransferase 5 JBrowse link NW_004955445 8,471,684 8,559,672 RGD:9068941
G B4galt6 beta-1,4-galactosyltransferase 6 JBrowse link NW_004955402 18,945,013 19,024,132 RGD:9068941
G Cntn2 contactin 2 JBrowse link NW_004955406 40,831,897 40,862,445 RGD:9068941
G Cntnap1 contactin associated protein 1 JBrowse link NW_004955451 16,535,924 16,547,800 RGD:9068941
G Hes5 hes family bHLH transcription factor 5 JBrowse link NW_004955486 8,700,212 8,701,581 RGD:9068941
G Id4 inhibitor of DNA binding 4, HLH protein JBrowse link NW_004955483 6,598,804 6,601,496 RGD:9068941
G Kcnj10 potassium voltage-gated channel subfamily J member 10 JBrowse link NW_004955468 11,828,525 11,860,365 RGD:9068941
G Mag myelin associated glycoprotein JBrowse link NW_004955468 4,584,068 4,598,772 RGD:9068941
G Myrf myelin regulatory factor JBrowse link NW_004955511 5,927,103 5,949,289 RGD:9068941
G Ncstn nicastrin JBrowse link NW_004955468 12,111,078 12,126,404 RGD:9068941
G Nkx6-2 NK6 homeobox 2 JBrowse link NW_004955477 10,386,033 10,387,423 RGD:9068941
G Plp1 proteolipid protein 1 JBrowse link NW_004955548 781,522 797,246 RGD:9068941
G Sox10 SRY-box 10 JBrowse link NW_004955413 24,313,311 24,323,112 RGD:9068941
myelin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fig4 FIG4 phosphoinositide 5-phosphatase JBrowse link NW_004955411 3,135,752 3,217,891 RGD:9068941
G Gpc1 glypican 1 JBrowse link NW_004955542 947,556 968,295 RGD:9068941
G Ilk integrin linked kinase JBrowse link NW_004955414 22,316,243 22,322,979 RGD:9068941
G Mpp5 membrane palmitoylated protein 5 JBrowse link NW_004955466 2,871,445 2,937,296 RGD:9068941
G Mtmr2 myotubularin related protein 2 JBrowse link NW_004955412 693,743 764,377 RGD:9068941
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing JBrowse link NW_004955457 6,749,226 6,841,855 RGD:9068941
G Pmp22 peripheral myelin protein 22 JBrowse link NW_004955467 2,422,181 2,456,925 RGD:9068941
myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcd1 ATP binding cassette subfamily D member 1 JBrowse link NW_004955580 459,715 475,363 RGD:9068941
G Abcd2 ATP binding cassette subfamily D member 2 JBrowse link NW_004955505 717,800 769,702 RGD:9068941
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link NW_004955440 3,456,165 3,460,024 RGD:9068941
G Epb41l3 erythrocyte membrane protein band 4.1 like 3 JBrowse link NW_004955402 5,459,586 5,674,745 RGD:9068941
myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acer3 alkaline ceramidase 3 JBrowse link NW_004955414 14,741,027 14,846,931 RGD:9068941
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 JBrowse link NW_004955450 703,874 744,782 RGD:9068941
G Adgrg6 adhesion G protein-coupled receptor G6 JBrowse link NW_004955436 17,804,548 17,931,667 RGD:9068941
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 JBrowse link NW_004955402 1,037,414 1,069,165 RGD:9068941
G Amigo1 adhesion molecule with Ig like domain 1 JBrowse link NW_004955435 12,918,270 12,930,362 RGD:9068941
G Atrn attractin JBrowse link NW_004955415 14,341,635 14,505,955 RGD:9068941
G Bcas1 breast carcinoma amplified sequence 1 JBrowse link NW_004955445 4,951,645 5,049,925 RGD:9068941
G Cldn5 claudin 5 JBrowse link NW_004955442 18,509,501 18,511,267 RGD:9068941
G Cmtm8 CKLF like MARVEL transmembrane domain containing 8 JBrowse link NW_004955430 23,638,734 23,728,365 RGD:9068941
G Egr2 early growth response 2 JBrowse link NW_004955425 16,055,748 16,068,429 RGD:9068941
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta JBrowse link NW_004955523 553,356 559,376 RGD:9068941
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta JBrowse link NW_004955469 9,328,900 9,334,463 RGD:9068941
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link NW_004955420 23,313,405 23,322,748 RGD:9068941
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link NW_004955451 14,442,816 14,456,009 RGD:9068941
G Fam126a family with sequence similarity 126 member A JBrowse link NW_004955410 25,274,360 25,342,112 RGD:9068941
G Gal3st1 galactose-3-O-sulfotransferase 1 JBrowse link NW_004955455 4,771,378 4,794,085 RGD:9068941
G Galc galactosylceramidase JBrowse link NW_004955438 10,667,807 10,704,386 RGD:9068941
G Gjc3 gap junction protein gamma 3 JBrowse link NW_004955573 944,440 951,440 RGD:9068941
G Hexb hexosaminidase subunit beta JBrowse link NW_004955425 25,942,341 25,961,312 RGD:9068941
G Jam3 junctional adhesion molecule 3 JBrowse link NW_004955412 34,901,850 34,967,394 RGD:9068941
G Kel Kell metallo-endopeptidase (Kell blood group) JBrowse link NW_004955494 668,188 688,036 RGD:9068941
G Klk6 kallikrein related peptidase 6 JBrowse link NW_004955558 1,501,806 1,509,461 RGD:9068941
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link NW_004955419 16,190,109 16,324,702 RGD:9068941
G Mal mal, T cell differentiation protein JBrowse link NW_004955470 3,372,577 3,396,868 RGD:9068941
G Mal2 mal, T cell differentiation protein 2 JBrowse link NW_004955417 25,069,847 25,096,132 RGD:9068941
G Mall mal, T cell differentiation protein like JBrowse link NW_004955470 3,313,152 3,344,950 RGD:9068941
G Marveld1 MARVEL domain containing 1 JBrowse link NW_004955507 3,787,404 3,787,976 RGD:9068941
G Mbp myelin basic protein JBrowse link NW_004955402 60,324,060 60,448,926 RGD:9068941
G Mpz myelin protein zero JBrowse link NW_004955468 13,041,911 13,047,026 RGD:9068941
G Myo5a myosin VA JBrowse link NW_004955409 2,409,503 2,530,539 RGD:9068941
G Nab1 NGFI-A binding protein 1 JBrowse link NW_004955403 8,456,572 8,487,749 RGD:9068941
G Nab2 NGFI-A binding protein 2 JBrowse link NW_004955458 4,826,464 4,832,487 RGD:9068941
G Nfasc neurofascin JBrowse link NW_004955406 40,632,971 40,814,930 RGD:9068941
G Olig2 oligodendrocyte transcription factor 2 JBrowse link NW_004955407 32,432,888 32,436,209 RGD:9068941
G Pllp plasmolipin JBrowse link NW_004955433 14,896,087 14,915,794 RGD:9068941
G Plp1 proteolipid protein 1 JBrowse link NW_004955548 781,522 797,246 RGD:9068941
G Pmp22 peripheral myelin protein 22 JBrowse link NW_004955467 2,422,181 2,456,925 RGD:9068941
G Psap prosaposin JBrowse link NW_004955437 19,667,252 19,683,669 RGD:9068941
G Sbf2 SET binding factor 2 JBrowse link NW_004955414 25,463,962 25,845,368 RGD:9068941
G Scn2a sodium voltage-gated channel alpha subunit 2 JBrowse link NW_004955449 8,722,043 8,846,165 RGD:9068941
G Scn8a sodium voltage-gated channel alpha subunit 8 JBrowse link NW_004955547 2,086,215 2,201,300 RGD:9068941
G Serinc5 serine incorporator 5 JBrowse link NW_004955418 29,502,562 29,573,966 RGD:9068941
G Slc8a3 solute carrier family 8 member A3 JBrowse link NW_004955466 220,346 359,627 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link NW_004955437 11,877,051 11,915,220 RGD:9068941
G Tsc1 TSC complex subunit 1 JBrowse link NW_004955513 2,197,037 2,244,992 RGD:9068941
G Tspan2 tetraspanin 2 JBrowse link NW_004955435 18,344,320 18,371,248 RGD:9068941
G Xk X-linked Kx blood group JBrowse link NW_004955587 668,871 725,829 RGD:9068941
G Znf24 zinc finger protein 24 JBrowse link NW_004955402 22,067,261 22,079,216 RGD:9068941
G Zscan26 zinc finger and SCAN domain containing 26 JBrowse link NW_004955465 13,626,552 13,638,819 RGD:9068941
myelination in peripheral nervous system term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam22 ADAM metallopeptidase domain 22 JBrowse link NW_004955432 5,306,018 5,536,282 RGD:9068941
G Adgrg6 adhesion G protein-coupled receptor G6 JBrowse link NW_004955436 17,804,548 17,931,667 RGD:9068941
G Arhgef10 Rho guanine nucleotide exchange factor 10 JBrowse link NW_004955403 57,820,003 57,907,324 RGD:9068941
G Cntnap1 contactin associated protein 1 JBrowse link NW_004955451 16,535,924 16,547,800 RGD:9068941
G Dag1 dystroglycan 1 JBrowse link NW_004955532 1,446,553 1,465,310 RGD:9068941
G Ilk integrin linked kinase JBrowse link NW_004955414 22,316,243 22,322,979 RGD:9068941
G Lgi4 leucine rich repeat LGI family member 4 JBrowse link NW_004955468 4,441,808 4,456,884 RGD:9068941
G Myoc myocilin JBrowse link NW_004955406 12,182,115 12,194,683 RGD:9068941
G Nf1 neurofibromin 1 JBrowse link NW_004955481 6,145,855 6,404,179 RGD:9068941
G Nrg1 neuregulin 1 JBrowse link NW_004955463 8,009,436 9,037,116 RGD:9068941
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link NW_004955432 2,284,283 2,629,631 RGD:9068941
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link NW_004955416 16,652,931 17,018,188 RGD:9068941
G Pard3 par-3 family cell polarity regulator JBrowse link NW_004955462 2,930,171 3,457,358 RGD:9068941
G Pou3f2 POU class 3 homeobox 2 JBrowse link NW_004955411 24,714,899 24,722,048 RGD:9068941
G Sirt2 sirtuin 2 JBrowse link NW_004955468 626,365 644,441 RGD:9068941
G Ski SKI proto-oncogene JBrowse link NW_004955486 8,857,693 8,921,821 RGD:9068941
negative regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctsc cathepsin C JBrowse link NW_004955414 5,062,355 5,092,631 RGD:9068941
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link NW_004955424 210,867 279,267 RGD:9068941
G Fig4 FIG4 phosphoinositide 5-phosphatase JBrowse link NW_004955411 3,135,752 3,217,891 RGD:9068941
G Klk8 kallikrein related peptidase 8 JBrowse link NW_004955558 1,479,383 1,484,209 RGD:9068941
G Mtmr2 myotubularin related protein 2 JBrowse link NW_004955412 693,743 764,377 RGD:9068941
G Pten phosphatase and tensin homolog JBrowse link NW_004955425 5,007,811 5,091,829 RGD:9068941
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link NW_004955437 11,877,051 11,915,220 RGD:9068941
paranodal junction assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link NW_004955457 13,624,590 13,938,427 RGD:9068941
G Cd9 CD9 molecule JBrowse link NW_004955413 3,891,874 3,924,065 RGD:9068941
G Cntnap1 contactin associated protein 1 JBrowse link NW_004955451 16,535,924 16,547,800 RGD:9068941
G Epb41l3 erythrocyte membrane protein band 4.1 like 3 JBrowse link NW_004955402 5,459,586 5,674,745 RGD:9068941
G Gnpat glyceronephosphate O-acyltransferase JBrowse link NW_004955492 7,489,080 7,519,590 RGD:9068941
G Nfasc neurofascin JBrowse link NW_004955406 40,632,971 40,814,930 RGD:9068941
G Ugt8 UDP glycosyltransferase 8 JBrowse link NW_004955428 24,800,854 24,864,904 RGD:9068941
peripheral nervous system myelin formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004955438 17,374,899 17,431,599 RGD:9068941
G Ncmap non-compact myelin associated protein JBrowse link NW_004955452 4,335,411 4,380,972 RGD:9068941
peripheral nervous system myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004955538 3,208,711 3,224,386 RGD:9068941
G Akt2 AKT serine/threonine kinase 2 JBrowse link NW_004955578 950,258 1,004,438 RGD:9068941
G Fa2h fatty acid 2-hydroxylase JBrowse link NW_004955484 2,726,496 2,775,763 RGD:9068941
G Mpp5 membrane palmitoylated protein 5 JBrowse link NW_004955466 2,871,445 2,937,296 RGD:9068941
G Ndrg1 N-myc downstream regulated 1 JBrowse link NW_004955461 7,787,068 7,836,380 RGD:9068941
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 JBrowse link NW_004955415 5,286,475 5,354,880 RGD:9068941
G Sod1 superoxide dismutase 1 JBrowse link NW_004955407 31,261,451 31,267,657 RGD:9068941
positive regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cst7 cystatin F JBrowse link NW_004955415 31,082,978 31,086,379 RGD:9068941
G Dag1 dystroglycan 1 JBrowse link NW_004955532 1,446,553 1,465,310 RGD:9068941
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004955438 17,374,899 17,431,599 RGD:9068941
G Hgf hepatocyte growth factor JBrowse link NW_004955410 4,114,280 4,181,953 RGD:9068941
G Mag myelin associated glycoprotein JBrowse link NW_004955468 4,584,068 4,598,772 RGD:9068941
G Myrf myelin regulatory factor JBrowse link NW_004955511 5,927,103 5,949,289 RGD:9068941
G Ncmap non-compact myelin associated protein JBrowse link NW_004955452 4,335,411 4,380,972 RGD:9068941
G Pard3 par-3 family cell polarity regulator JBrowse link NW_004955462 2,930,171 3,457,358 RGD:9068941
G Rnf10 ring finger protein 10 JBrowse link NW_004955455 11,074,118 11,119,771 RGD:9068941
G S100b S100 calcium binding protein B JBrowse link NW_004955407 42,972,584 42,980,510 RGD:9068941
G Slc25a12 solute carrier family 25 member 12 JBrowse link NW_004955449 3,093,603 3,182,513 RGD:9068941
G Sox10 SRY-box 10 JBrowse link NW_004955413 24,313,311 24,323,112 RGD:9068941
G Tenm4 teneurin transmembrane protein 4 JBrowse link NW_004955414 12,649,128 13,364,523 RGD:9068941
G Wasf3 WASP family member 3 JBrowse link NW_004955497 6,100,633 6,190,639 RGD:9068941
regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004955538 3,208,711 3,224,386 RGD:9068941
G Ctnnb1 catenin beta 1 JBrowse link NW_004955420 29,030,716 29,047,447 RGD:9068941
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link NW_004955420 13,068,289 13,273,805 RGD:9068941
G Hes5 hes family bHLH transcription factor 5 JBrowse link NW_004955486 8,700,212 8,701,581 RGD:9068941
G Kif14 kinesin family member 14 JBrowse link NW_004955406 36,732,135 36,791,756 RGD:9068941
G Lgi4 leucine rich repeat LGI family member 4 JBrowse link NW_004955468 4,441,808 4,456,884 RGD:9068941
G Mtor mechanistic target of rapamycin kinase JBrowse link NW_004955486 2,487,642 2,599,694 RGD:9068941
G Nkx6-2 NK6 homeobox 2 JBrowse link NW_004955477 10,386,033 10,387,423 RGD:9068941
G Rara retinoic acid receptor alpha JBrowse link NW_004955451 14,876,663 14,917,134 RGD:9068941
G Rarb retinoic acid receptor beta JBrowse link NW_004955430 17,067,536 17,457,558 RGD:9068941
G Rarg retinoic acid receptor gamma JBrowse link NW_004955458 480,257 501,172 RGD:9068941
G Sirt2 sirtuin 2 JBrowse link NW_004955468 626,365 644,441 RGD:9068941
G Tenm4 teneurin transmembrane protein 4 JBrowse link NW_004955414 12,649,128 13,364,523 RGD:9068941
G Tg thyroglobulin JBrowse link NW_004955461 7,487,268 7,703,458 RGD:9068941
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link NW_004955486 1,790,531 1,817,986 RGD:9068941
G Tymp thymidine phosphorylase JBrowse link NW_004955413 33,505,424 33,509,095 RGD:9068941
G Zpr1 ZPR1 zinc finger JBrowse link NW_004955412 18,117,957 18,127,552 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14499
    cellular process 13308
      ensheathment of neurons 125
        axon ensheathment + 125
        ensheathment of neuronal cell bodies 0
Path 2
Term Annotations click to browse term
  biological_process 14499
    developmental process 5690
      anatomical structure development 5342
        multicellular organism development 4907
          system development 4397
            nervous system development 2262
              ensheathment of neurons 125
                axon ensheathment + 125
                ensheathment of neuronal cell bodies 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.