ONTOLOGY REPORT - ANNOTATIONS


Term:ensheathment of neurons
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Accession:GO:0007272 term browser browse the term
Definition:The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.
Synonyms:related_synonym: ionic insulation of neurons by glial cells


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axon ensheathment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MBP myelin basic protein JBrowse link 18 76,978,833 77,133,708 RGD:2290271
G PLP1 proteolipid protein 1 JBrowse link X 103,776,506 103,792,619 RGD:2290271
G POU3F1 POU class 3 homeobox 1 JBrowse link 1 38,043,851 38,046,778 RGD:2290271
G PPARD peroxisome proliferator activated receptor delta JBrowse link 6 35,342,558 35,428,191 RGD:2290271
G PRX periaxin JBrowse link 19 40,393,762 40,414,718 RGD:2290271
central nervous system myelin formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 45,349,837 45,370,647 RGD:2290271
G TENM4 teneurin transmembrane protein 4 JBrowse link 11 78,653,283 79,441,019 RGD:2290271
G TLR2 toll like receptor 2 JBrowse link 4 153,684,080 153,710,643 RGD:2290271
central nervous system myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLU clusterin JBrowse link 8 27,596,917 27,615,031 RGD:2290271
G FA2H fatty acid 2-hydroxylase JBrowse link 16 74,712,955 74,774,831 RGD:2290271
G MYRF myelin regulatory factor JBrowse link 11 61,752,617 61,788,518 RGD:2290271
G PTEN phosphatase and tensin homolog JBrowse link 10 87,863,438 87,971,930 RGD:2290271
central nervous system myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASPA aspartoacylase JBrowse link 17 3,473,646 3,502,534 RGD:2290271
G B4GALT5 beta-1,4-galactosyltransferase 5 JBrowse link 20 49,632,945 49,713,884 RGD:2290271
G B4GALT6 beta-1,4-galactosyltransferase 6 JBrowse link 18 31,621,036 31,724,670 RGD:2290271
G CNTN2 contactin 2 JBrowse link 1 205,042,937 205,078,272 RGD:2290271
G CNTNAP1 contactin associated protein 1 JBrowse link 17 42,679,767 42,699,993 RGD:2290271
G HES5 hes family bHLH transcription factor 5 JBrowse link 1 2,528,745 2,530,554 RGD:2290271
G ID4 inhibitor of DNA binding 4, HLH protein JBrowse link 6 19,837,370 19,842,200 RGD:2290271
G KCNJ10 potassium voltage-gated channel subfamily J member 10 JBrowse link 1 160,037,467 160,070,261 RGD:2290271
G MAG myelin associated glycoprotein JBrowse link 19 35,292,086 35,313,807 RGD:2290271
G MYRF myelin regulatory factor JBrowse link 11 61,752,617 61,788,518 RGD:2290271
G NCSTN nicastrin JBrowse link 1 160,343,273 160,358,952 RGD:2290271
G NKX6-2 NK6 homeobox 2 JBrowse link 10 132,782,229 132,786,033 RGD:2290271
G PLP1 proteolipid protein 1 JBrowse link X 103,776,506 103,792,619 RGD:2290271
G SOX10 SRY-box 10 JBrowse link 22 37,972,312 37,984,532 RGD:2290271
myelin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FIG4 FIG4 phosphoinositide 5-phosphatase JBrowse link 6 109,691,221 109,825,431 RGD:2290271
G GPC1 glypican 1 JBrowse link 2 240,435,698 240,468,078 RGD:2290271
G ILK integrin linked kinase JBrowse link 11 6,603,708 6,610,874 RGD:2290271
G MPP5 membrane palmitoylated protein 5 JBrowse link 14 67,241,295 67,336,061 RGD:2290271
G MTMR2 myotubularin related protein 2 JBrowse link 11 95,832,880 95,924,207 RGD:2290271
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing JBrowse link 2 208,266,178 208,358,751 RGD:2290271
G PMP22 peripheral myelin protein 22 JBrowse link 17 15,229,777 15,265,373 RGD:2290271
myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCD1 ATP binding cassette subfamily D member 1 JBrowse link X 153,724,851 153,744,762 RGD:2290271
G ABCD2 ATP binding cassette subfamily D member 2 JBrowse link 12 39,530,965 39,651,333 RGD:2290271
G CXCR4 C-X-C motif chemokine receptor 4 JBrowse link 2 136,114,349 136,118,155 RGD:2290271
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 JBrowse link 18 5,392,276 5,630,663 RGD:2290271
myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACER3 alkaline ceramidase 3 JBrowse link 11 76,860,873 77,026,797 RGD:2290271
G ACSBG1 acyl-CoA synthetase bubblegum family member 1 JBrowse link 15 78,167,468 78,234,707 RGD:2290271
G ADGRG6 adhesion G protein-coupled receptor G6 JBrowse link 6 142,301,919 142,446,266 RGD:2290271
G AFG3L2 AFG3 like matrix AAA peptidase subunit 2 JBrowse link 18 12,328,944 12,377,309 RGD:2290271
G AMIGO1 adhesion molecule with Ig like domain 1 JBrowse link 1 109,504,175 109,509,751 RGD:2290271
G ATRN attractin JBrowse link 20 3,471,018 3,651,122 RGD:2290271
G BCAS1 breast carcinoma amplified sequence 1 JBrowse link 20 53,943,538 54,070,765 RGD:2290271
G CLDN5 claudin 5 JBrowse link 22 19,523,024 19,527,545 RGD:2290271
G CMTM8 CKLF like MARVEL transmembrane domain containing 8 JBrowse link 3 32,238,679 32,370,325 RGD:2290271
G DHH desert hedgehog signaling molecule JBrowse link 12 49,086,656 49,094,819 RGD:2290271
G EGR2 early growth response 2 JBrowse link 10 62,811,996 62,819,167 RGD:2290271
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta JBrowse link 14 75,002,909 75,009,591 RGD:2290271
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta JBrowse link 2 27,364,352 27,370,457 RGD:2290271
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link 3 184,135,022 184,145,311 RGD:2290271
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 17 39,688,084 39,728,662 RGD:2290271
G FAM126A family with sequence similarity 126 member A JBrowse link 7 22,895,848 23,014,151 RGD:2290271
G GAL3ST1 galactose-3-O-sulfotransferase 1 JBrowse link 22 30,554,635 30,574,588 RGD:2290271
G GALC galactosylceramidase JBrowse link 14 87,933,014 87,993,665 RGD:2290271
G GJC3 gap junction protein gamma 3 JBrowse link 7 99,923,269 99,929,620 RGD:2290271
G HEXB hexosaminidase subunit beta JBrowse link 5 74,640,023 74,721,288 RGD:2290271
G JAM3 junctional adhesion molecule 3 JBrowse link 11 134,068,925 134,151,757 RGD:2290271
G KEL Kell metallo-endopeptidase (Kell blood group) JBrowse link 7 142,941,114 142,962,416 RGD:2290271
G KLK6 kallikrein related peptidase 6 JBrowse link 19 50,958,631 50,969,673 RGD:2290271
G LPAR1 lysophosphatidic acid receptor 1 JBrowse link 9 110,873,252 111,039,259 RGD:2290271
G MAL mal, T cell differentiation protein JBrowse link 2 95,025,655 95,053,992 RGD:2290271
G MAL2 mal, T cell differentiation protein 2 (gene/pseudogene) JBrowse link 8 119,208,371 119,245,673 RGD:2290271
G MALL mal, T cell differentiation protein like JBrowse link 2 110,083,870 110,118,139 RGD:2290271
G MARVELD1 MARVEL domain containing 1 JBrowse link 10 97,713,708 97,718,152 RGD:2290271
G MBP myelin basic protein JBrowse link 18 76,978,833 77,133,708 RGD:2290271
G MPZ myelin protein zero JBrowse link 1 161,303,594 161,309,972 RGD:2290271
G MYO5A myosin VA JBrowse link 15 52,307,283 52,529,050 RGD:2290271
G NAB1 NGFI-A binding protein 1 JBrowse link 2 190,648,860 190,692,766 RGD:2290271
G NAB2 NGFI-A binding protein 2 JBrowse link 12 57,088,894 57,095,476 RGD:2290271
G NFASC neurofascin JBrowse link 1 204,828,652 205,022,822 RGD:2290271
G OLIG2 oligodendrocyte transcription factor 2 JBrowse link 21 33,025,908 33,029,196 RGD:2290271
G PLLP plasmolipin JBrowse link 16 57,256,097 57,284,672 RGD:2290271
G PLP1 proteolipid protein 1 JBrowse link X 103,776,506 103,792,619 RGD:2290271
G PMP22 peripheral myelin protein 22 JBrowse link 17 15,229,777 15,265,373 RGD:2290271
G PSAP prosaposin JBrowse link 10 71,816,283 71,851,375 RGD:2290271
G QKI QKI, KH domain containing RNA binding JBrowse link 6 163,414,486 163,578,596 RGD:2290271
G SBF2 SET binding factor 2 JBrowse link 11 9,778,667 10,294,207 RGD:2290271
G SCN2A sodium voltage-gated channel alpha subunit 2 JBrowse link 2 165,208,056 165,392,310 RGD:2290271
G SCN8A sodium voltage-gated channel alpha subunit 8 JBrowse link 12 51,589,958 51,812,864 RGD:2290271
G SERINC5 serine incorporator 5 JBrowse link 5 80,111,227 80,256,082 RGD:2290271
G SLC8A3 solute carrier family 8 member A3 JBrowse link 14 70,044,217 70,189,626 RGD:2290271
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,883 RGD:2290271
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 47,231,527 47,309,947 RGD:2290271
G TSC1 TSC complex subunit 1 JBrowse link 9 132,891,348 132,945,269 RGD:2290271
G TSPAN2 tetraspanin 2 JBrowse link 1 115,048,011 115,089,501 RGD:2290271
G XK X-linked Kx blood group JBrowse link X 37,685,686 37,732,130 RGD:2290271
G ZNF24 zinc finger protein 24 JBrowse link 18 35,332,208 35,344,467 RGD:2290271
G ZSCAN26 zinc finger and SCAN domain containing 26 JBrowse link 6 28,267,010 28,278,224 RGD:2290271
myelination in peripheral nervous system term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAM22 ADAM metallopeptidase domain 22 JBrowse link 7 87,934,143 88,202,889 RGD:2290271
G ADGRG6 adhesion G protein-coupled receptor G6 JBrowse link 6 142,301,919 142,446,266 RGD:2290271
G ARHGEF10 Rho guanine nucleotide exchange factor 10 JBrowse link 8 1,823,976 1,958,641 RGD:2290271
G CNTNAP1 contactin associated protein 1 JBrowse link 17 42,679,767 42,699,993 RGD:2290271
G DAG1 dystroglycan 1 JBrowse link 3 49,468,703 49,535,618 RGD:2290271
G ILK integrin linked kinase JBrowse link 11 6,603,708 6,610,874 RGD:2290271
G LGI4 leucine rich repeat LGI family member 4 JBrowse link 19 35,124,513 35,135,274 RGD:2290271
G MYOC myocilin JBrowse link 1 171,635,417 171,652,633 RGD:2290271
G NF1 neurofibromin 1 JBrowse link 17 31,094,927 31,377,677 RGD:2290271
G NRG1 neuregulin 1 JBrowse link 8 31,639,222 32,771,716 RGD:2290271
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 9 84,668,458 85,027,070 RGD:2290271
G NTRK3 neurotrophic receptor tyrosine kinase 3 JBrowse link 15 87,859,749 88,256,796 RGD:2290271
G PARD3 par-3 family cell polarity regulator JBrowse link 10 34,109,560 34,815,325 RGD:2290271
G POU3F1 POU class 3 homeobox 1 JBrowse link 1 38,043,851 38,046,778 RGD:2290271
G POU3F2 POU class 3 homeobox 2 JBrowse link 6 98,834,704 98,838,790 RGD:2290271
G SIRT2 sirtuin 2 JBrowse link 19 38,878,555 38,899,862 RGD:2290271
G SKI SKI proto-oncogene JBrowse link 1 2,228,695 2,310,213 RGD:2290271
negative regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CTSC cathepsin C JBrowse link 11 88,293,592 88,337,787 RGD:2290271
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 2 88,556,740 88,627,576 RGD:2290271
G FIG4 FIG4 phosphoinositide 5-phosphatase JBrowse link 6 109,691,221 109,825,431 RGD:2290271
G KLK8 kallikrein related peptidase 8 JBrowse link 19 50,996,008 51,001,702 RGD:2290271
G MTMR2 myotubularin related protein 2 JBrowse link 11 95,832,880 95,924,207 RGD:2290271
G PTEN phosphatase and tensin homolog JBrowse link 10 87,863,438 87,971,930 RGD:2290271
G TMEM98 transmembrane protein 98 JBrowse link 17 32,927,910 32,941,649 RGD:2290271
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 47,231,527 47,309,947 RGD:2290271
paranodal junction assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANK2 ankyrin 2 JBrowse link 4 112,706,018 113,383,740 RGD:2290271
G CD9 CD9 molecule JBrowse link 12 6,199,707 6,238,271 RGD:2290271
G CNTNAP1 contactin associated protein 1 JBrowse link 17 42,679,767 42,699,993 RGD:2290271
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 JBrowse link 18 5,392,276 5,630,663 RGD:2290271
G GNPAT glyceronephosphate O-acyltransferase JBrowse link 1 231,241,173 231,277,973 RGD:2290271
G NFASC neurofascin JBrowse link 1 204,828,652 205,022,822 RGD:2290271
G UGT8 UDP glycosyltransferase 8 JBrowse link 4 114,598,402 114,687,914 RGD:2290271
peripheral nervous system myelin formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:2290271
G NCMAP non-compact myelin associated protein JBrowse link 1 24,556,076 24,609,328 RGD:2290271
peripheral nervous system myelin maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,743 RGD:2290271
G AKT2 AKT serine/threonine kinase 2 JBrowse link 19 40,230,317 40,285,531 RGD:2290271
G FA2H fatty acid 2-hydroxylase JBrowse link 16 74,712,955 74,774,831 RGD:2290271
G MPP5 membrane palmitoylated protein 5 JBrowse link 14 67,241,295 67,336,061 RGD:2290271
G NDRG1 N-myc downstream regulated 1 JBrowse link 8 133,237,171 133,297,587 RGD:2290271
G SH3TC2 SH3 domain and tetratricopeptide repeats 2 JBrowse link 5 148,982,150 149,063,174 RGD:2290271
G SOD1 superoxide dismutase 1 JBrowse link 21 31,659,622 31,668,931 RGD:2290271
positive regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CST7 cystatin F JBrowse link 20 24,949,230 24,959,928 RGD:2290271
G DAG1 dystroglycan 1 JBrowse link 3 49,468,703 49,535,618 RGD:2290271
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:2290271
G HGF hepatocyte growth factor JBrowse link 7 81,699,006 81,770,438 RGD:2290271
G ITGAX integrin subunit alpha X JBrowse link 16 31,355,134 31,382,997 RGD:2290271
G MAG myelin associated glycoprotein JBrowse link 19 35,292,086 35,313,807 RGD:2290271
G MYRF myelin regulatory factor JBrowse link 11 61,752,617 61,788,518 RGD:2290271
G NCMAP non-compact myelin associated protein JBrowse link 1 24,556,076 24,609,328 RGD:2290271
G PARD3 par-3 family cell polarity regulator JBrowse link 10 34,109,560 34,815,325 RGD:2290271
G RNF10 ring finger protein 10 JBrowse link 12 120,534,329 120,577,594 RGD:2290271
G S100B S100 calcium binding protein B JBrowse link 21 46,598,618 46,605,243 RGD:2290271
G SLC25A12 solute carrier family 25 member 12 JBrowse link 2 171,783,405 171,894,306 RGD:2290271
G SOX10 SRY-box 10 JBrowse link 22 37,972,312 37,984,532 RGD:2290271
G TENM4 teneurin transmembrane protein 4 JBrowse link 11 78,653,283 79,441,019 RGD:2290271
G TNFRSF1B TNF receptor superfamily member 1B JBrowse link 1 12,166,948 12,209,222 RGD:2290271
G WASF3 WASP family member 3 JBrowse link 13 26,539,139 26,688,945 RGD:2290271
regulation of myelination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,743 RGD:2290271
G CTNNB1 catenin beta 1 JBrowse link 3 41,199,422 41,240,453 RGD:2290271
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 3 197,042,560 197,299,272 RGD:2290271
G HES5 hes family bHLH transcription factor 5 JBrowse link 1 2,528,745 2,530,554 RGD:2290271
G KIF14 kinesin family member 14 JBrowse link 1 200,551,497 200,620,791 RGD:2290271
G LGI4 leucine rich repeat LGI family member 4 JBrowse link 19 35,124,513 35,135,274 RGD:2290271
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,106,531 11,273,497 RGD:2290271
G NKX6-2 NK6 homeobox 2 JBrowse link 10 132,782,229 132,786,033 RGD:2290271
G PTN pleiotrophin JBrowse link 7 137,227,341 137,343,990 RGD:2290271
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 JBrowse link 7 121,873,105 122,062,036 RGD:2290271
G RARA retinoic acid receptor alpha JBrowse link 17 40,309,171 40,357,643 RGD:2290271
G RARB retinoic acid receptor beta JBrowse link 3 24,829,323 25,597,932 RGD:2290271
G RARG retinoic acid receptor gamma JBrowse link 12 53,210,566 53,232,256 RGD:2290271
G SIRT2 sirtuin 2 JBrowse link 19 38,878,555 38,899,862 RGD:2290271
G TENM4 teneurin transmembrane protein 4 JBrowse link 11 78,653,283 79,441,019 RGD:2290271
G TG thyroglobulin JBrowse link 8 132,866,943 133,134,902 RGD:2290271
G TNFRSF1B TNF receptor superfamily member 1B JBrowse link 1 12,166,948 12,209,222 RGD:2290271
G TYMP thymidine phosphorylase JBrowse link 22 50,525,752 50,530,085 RGD:2290271
G ZPR1 ZPR1 zinc finger JBrowse link 11 116,778,189 116,789,272 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17615
    cellular process 15892
      ensheathment of neurons 132
        axon ensheathment + 132
        ensheathment of neuronal cell bodies 0
Path 2
Term Annotations click to browse term
  biological_process 17615
    developmental process 6336
      anatomical structure development 5926
        multicellular organism development 5438
          system development 4873
            nervous system development 2403
              ensheathment of neurons 132
                axon ensheathment + 132
                ensheathment of neuronal cell bodies 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.