ONTOLOGY REPORT - ANNOTATIONS


Term:acrosome reaction
go back to main search page
Accession:GO:0007340 term browser browse the term
Definition:The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.
Comment:If the release of the acrosome content occurs before the sperm reaches the zona pellucida, consider using premature acrosome loss.
Synonyms:xref: Wikipedia:Acrosome_reaction


show annotations for term's descendants       view all columns           Sort by:
 
acrosome reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABHD2 abhydrolase domain containing 2 JBrowse link 15 86,987,070 87,095,823 RGD:9068941
G ACR acrosin JBrowse link 22 50,085,719 50,092,869 RGD:9068941
G ADCY3 adenylate cyclase 3 JBrowse link 2A 24,908,108 25,009,163 RGD:9068941
G AKAP3 A-kinase anchoring protein 3 JBrowse link 12 4,655,004 4,687,239 RGD:9068941
G GLRA1 glycine receptor alpha 1 JBrowse link 5 153,248,488 153,350,573 RGD:9068941
G GLRB glycine receptor beta JBrowse link 4 161,237,189 161,333,035 RGD:9068941
G PCSK4 proprotein convertase subtilisin/kexin type 4 JBrowse link 19 1,452,597 1,466,539 RGD:9068941
G PKDREJ polycystin family receptor for egg jelly JBrowse link 22 45,320,969 45,328,048 RGD:9068941
G PLCD4 phospholipase C delta 4 JBrowse link 2B 224,461,261 224,490,345 RGD:9068941
G PRND prion like protein doppel JBrowse link 20 4,545,862 4,552,299 RGD:9068941
G ROPN1B rhophilin associated tail protein 1B JBrowse link 3 130,351,601 130,365,393 RGD:9068941
G SPESP1 sperm equatorial segment protein 1 JBrowse link 15 66,651,277 66,667,511 RGD:9068941
G STX2 syntaxin 2 JBrowse link 12 132,612,870 132,650,554 RGD:9068941
G SYT6 synaptotagmin 6 JBrowse link 1 123,453,698 123,514,804 RGD:9068941
G SYT8 synaptotagmin 8 JBrowse link 11 1,899,325 1,905,764 RGD:9068941
G TNP2 transition protein 2 JBrowse link 16 11,431,694 11,433,158 RGD:9068941
G TRIM36 tripartite motif containing 36 JBrowse link 5 116,279,568 116,335,848 RGD:9068941
acrosomal vesicle exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EQTN equatorin JBrowse link 9 27,738,315 27,750,736 RGD:9068941
G LOC100985164 regulating synaptic membrane exocytosis protein 1 JBrowse link 6 73,304,152 73,523,422 RGD:9068941
G RAB3A RAB3A, member RAS oncogene family JBrowse link 19 18,649,166 18,656,768 RGD:9068941
G SYT6 synaptotagmin 6 JBrowse link 1 123,453,698 123,514,804 RGD:9068941
G UNC13B unc-13 homolog B JBrowse link 9 35,817,353 36,059,895 RGD:9068941
G ZP4 zona pellucida glycoprotein 4 JBrowse link 1 218,433,473 218,442,383 RGD:9068941
acrosome matrix dispersal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACR acrosin JBrowse link 22 50,085,719 50,092,869 RGD:9068941
negative regulation of acrosome reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) JBrowse link 5 149,702,870 149,721,406 RGD:9068941
positive regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HYAL3 hyaluronidase 3 JBrowse link 3 51,456,173 51,462,815 RGD:9068941
positive regulation of acrosome reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CACNA1H calcium voltage-gated channel subunit alpha1 H JBrowse link 16 1,195,991 1,222,917 RGD:9068941
G CCDC87 coiled-coil domain containing 87 JBrowse link 11 65,270,801 65,273,720 RGD:9068941
G GLRA1 glycine receptor alpha 1 JBrowse link 5 153,248,488 153,350,573 RGD:9068941
G IQCF1 IQ motif containing F1 JBrowse link 3 53,068,288 53,076,768 RGD:9068941
G PLB1 phospholipase B1 JBrowse link 2A 28,584,636 28,730,640 RGD:9068941
G PLCB1 phospholipase C beta 1 JBrowse link 20 7,887,773 8,636,019 RGD:9068941
G PRSS37 serine protease 37 JBrowse link 7 146,236,906 146,242,157 RGD:9068941
G ZP4 zona pellucida glycoprotein 4 JBrowse link 1 218,433,473 218,442,383 RGD:9068941
regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G STXBP1 syntaxin binding protein 1 JBrowse link 9 127,434,080 127,483,971 RGD:9068941
regulation of acrosome reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B4GALT1 beta-1,4-galactosyltransferase 1 JBrowse link 9 33,697,551 33,754,192 RGD:9068941
G CRISP1 cysteine rich secretory protein 1 JBrowse link 6 50,665,193 50,712,092 RGD:9068941
G SERPINA10 serpin family A member 10 JBrowse link 14 94,248,362 94,258,301 RGD:9068941
G SPINK1 serine peptidase inhibitor, Kazal type 1 JBrowse link 5 149,282,828 149,297,469 RGD:9068941
G ZP2 zona pellucida glycoprotein 2 JBrowse link 16 21,227,285 21,244,316 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15692
    reproductive process 1393
      acrosome reaction 36
        acrosomal vesicle exocytosis + 8
        acrosome matrix dispersal 1
        membrane fusion involved in acrosome reaction 0
        negative regulation of acrosome reaction 1
        positive regulation of acrosome reaction + 9
        positive regulation of actin filament depolymerization involved in acrosome reaction 0
        positive regulation of actin filament polymerization involved in acrosome reaction 0
        protein localization involved in acrosome reaction 0
        regulation of acrosome reaction + 16
Path 2
Term Annotations click to browse term
  biological_process 15692
    reproduction 1396
      reproductive process 1393
        multi-organism reproductive process 951
          sexual reproduction 793
            fertilization 173
              single fertilization 140
                acrosome reaction 36
                  acrosomal vesicle exocytosis + 8
                  acrosome matrix dispersal 1
                  membrane fusion involved in acrosome reaction 0
                  negative regulation of acrosome reaction 1
                  positive regulation of acrosome reaction + 9
                  positive regulation of actin filament depolymerization involved in acrosome reaction 0
                  positive regulation of actin filament polymerization involved in acrosome reaction 0
                  protein localization involved in acrosome reaction 0
                  regulation of acrosome reaction + 16
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.