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ONTOLOGY REPORT - ANNOTATIONS


Term:penetration of zona pellucida
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Accession:GO:0007341 term browser browse the term
Definition:The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.


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penetration of zona pellucida term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acr acrosin TAS
ISO
IMP
MGI:MGI:2180087|MGI:MGI:2429958|MGI:MGI:96945 (MGI:MGI:3042304|PMID:15051954), (MGI:MGI:69844|PMID:7989357), (MGI:MGI:86042|PMID:9041140) RGD PMID:7989357, PMID:9041140, PMID:15051954, PMID:8037773, PMID:28859281 MGI:MGI:3042304, MGI:MGI:69844, MGI:MGI:86042, RGD:1299864, RGD:13464336 NCBI chr 7:130,541,320...130,548,356
Ensembl chr 7:130,542,202...130,548,356
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 ISO
IEA
MGI:MGI:2178779 (MGI:MGI:1098917|PMID:9374408)
GO_REF:0000107
RGD
Ensembl
PMID:9374408 GO_REF:0000107, MGI:MGI:1098917 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G Dkkl1 dickkopf like acrosomal protein 1 ISO (MGI:MGI:4438468|PMID:19596312) RGD PMID:19596312 MGI:MGI:4438468 NCBI chr 1:101,205,426...101,210,675
Ensembl chr 1:101,205,426...101,210,675
JBrowse link
G Hexb hexosaminidase subunit beta ISO
IEA
(MGI:MGI:3582046|PMID:8269854)
GO_REF:0000107
RGD
Ensembl
PMID:8269854 GO_REF:0000107, MGI:MGI:3582046 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hyal3 hyaluronidase 3 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4834982|PMID:20586096)
Ensembl
UniProt
RGD
PMID:20586096 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4834982 NCBI chr 8:116,336,512...116,342,147
Ensembl chr 8:116,336,512...116,342,146
JBrowse link
G Hyal5 hyaluronoglucosaminidase 5 ISO (MGI:MGI:3611697|PMID:16330764) RGD PMID:16330764 MGI:MGI:3611697 NCBI chr 4:52,232,565...52,319,777
Ensembl chr 4:52,235,811...52,275,936
JBrowse link
G Pithd1 PITH domain containing 1 ISO MGI:MGI:6416147 (MGI:MGI:6392185|PMID:31915251) RGD PMID:31915251 MGI:MGI:6392185 NCBI chr 5:154,322,562...154,333,080
Ensembl chr 5:154,322,551...154,332,940
JBrowse link
G Smcp sperm mitochondria-associated cysteine-rich protein ISO MGI:MGI:2387973|MGI:MGI:87884 (MGI:MGI:2386493|PMID:11940662), (MGI:MGI:3042304|PMID:15051954) RGD PMID:11940662, PMID:15051954 MGI:MGI:2386493, MGI:MGI:3042304 NCBI chr 2:192,775,425...192,780,631
Ensembl chr 2:192,775,437...192,780,631
JBrowse link
G Tbxt T-box transcription factor T ISO MGI:MGI:1856570|MGI:MGI:1856722 (MGI:MGI:71219|PMID:7883069) RGD PMID:7883069 MGI:MGI:71219 NCBI chr 1:52,887,067...52,900,691
Ensembl chr 1:52,887,067...52,894,832
JBrowse link
G Tnp2 transition protein 2 ISO
IBA
IEA
MGI:MGI:2180779 (MGI:MGI:2180725|PMID:11385107)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:11385107, PMID:21873635 GO_REF:0000107, MGI:MGI:2180725, RGD:13792537 NCBI chr10:4,953,898...4,954,626
Ensembl chr10:4,953,879...4,954,624
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    multi-organism process 1260
      multi-multicellular organism process 337
        penetration of zona pellucida 10
Path 2
Term Annotations click to browse term
  biological_process 20014
    reproduction 1788
      reproductive process 1785
        multi-organism reproductive process 1238
          sexual reproduction 982
            fertilization 195
              single fertilization 150
                penetration of zona pellucida 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.