ONTOLOGY REPORT - ANNOTATIONS


Term:neuroblast proliferation
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Accession:GO:0007405 term browser browse the term
Definition:The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
Synonyms:alt_id: GO:0043349;   GO:0043350
 only_in_taxon: NCBITaxon:33208 ! Metazoa


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neuroblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 10 39,654,771 39,717,592 RGD:1624291
RGD:1600115
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
G Dagla diacylglycerol lipase, alpha JBrowse link 1 226,297,013 226,353,712 RGD:1624291
RGD:1600115
G Daglb diacylglycerol lipase, beta JBrowse link 12 13,113,073 13,157,748 RGD:1624291
RGD:1600115
G Eml1 EMAP like 1 JBrowse link 6 132,367,342 132,450,488 RGD:1600115
RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 7 60,128,506 60,210,482 RGD:1624291
RGD:1600115
G Fzd9 frizzled class receptor 9 JBrowse link 12 24,473,981 24,476,295 RGD:1624291
RGD:1600115
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:2315620
G Hhip Hedgehog-interacting protein JBrowse link 19 31,525,134 31,614,487 RGD:1624291
RGD:1600115
G Id4 inhibitor of DNA binding 4, HLH protein JBrowse link 17 16,692,557 16,695,126 RGD:1624291
RGD:1600115
G Ifrd1 interferon-related developmental regulator 1 JBrowse link 6 60,132,025 60,151,354 RGD:729202
G Kcna1 potassium voltage-gated channel subfamily A member 1 JBrowse link 4 159,190,781 159,192,526 RGD:1624291
RGD:1600115
G Nde1 nudE neurodevelopment protein 1 JBrowse link 10 860,513 904,624 RGD:1624291
RGD:1600115
G Neurod4 neuronal differentiation 4 JBrowse link 7 9,699,964 9,712,067 RGD:1624291
RGD:1600115
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:1624291
G Numbl NUMB-like, endocytic adaptor protein JBrowse link 1 84,067,841 84,091,659 RGD:1624291
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 JBrowse link 10 61,456,144 61,577,412 RGD:1624291
RGD:1600115
G Plxnb2 plexin B2 JBrowse link 7 130,135,484 130,161,568 RGD:1624291
RGD:1600115
G Racgap1 Rac GTPase-activating protein 1 JBrowse link 7 141,277,303 141,308,849 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
asymmetric neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
RGD:1600115
G Sox5 SRY box 5 JBrowse link 4 178,062,267 179,031,991 RGD:1624291
RGD:1600115
G Tead3 TEA domain transcription factor 3 JBrowse link 20 7,911,562 7,930,949 RGD:1624291
establishment of neuroblast polarity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dock7 dedicator of cytokinesis 7 JBrowse link 5 117,595,194 117,780,844 RGD:1624291
RGD:1600115
G Fgf13 fibroblast growth factor 13 JBrowse link X 142,053,648 142,589,274 RGD:1624291
RGD:1600115
G Rab10 RAB10, member RAS oncogene family JBrowse link 6 27,668,387 27,721,120 RGD:8553614
forebrain neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspm abnormal spindle microtubule assembly JBrowse link 13 56,546,021 56,591,793 RGD:1624291
RGD:1600115
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of neuroblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:1624291
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
RGD:1600115
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:1624291
RGD:1600115
G Kctd11 potassium channel tetramerization domain containing 11 JBrowse link 10 56,489,552 56,491,715 RGD:1624291
RGD:1600115
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Ptn pleiotrophin JBrowse link 4 64,239,156 64,330,996 RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1579761
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
RGD:1600115
G Vax1 ventral anterior homeobox 1 JBrowse link 1 280,334,897 280,338,813 RGD:1624291
RGD:1600115
neuroblast division in subventricular zone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akna AT-hook transcription factor JBrowse link 5 79,184,087 79,232,370 RGD:1600115
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:1600115
RGD:1624291
G Numbl NUMB-like, endocytic adaptor protein JBrowse link 1 84,067,841 84,091,659 RGD:1600115
RGD:1624291
positive regulation of neuroblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspm abnormal spindle microtubule assembly JBrowse link 13 56,546,021 56,591,793 RGD:1624291
RGD:1600115
G Bex1 brain expressed, X-linked 1 JBrowse link X 106,761,388 106,771,656 RGD:8554704
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1600115
RGD:1624291
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:9491804
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:9491804
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
G Disc1 DISC1 scaffold protein JBrowse link 19 57,818,838 58,069,992 RGD:1624291
RGD:1600115
G Dmrta2 DMRT-like family A2 JBrowse link 5 129,754,295 129,760,045 RGD:1624291
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1624291
RGD:1600115
G Foxg1 forkhead box G1 JBrowse link 6 69,971,227 69,974,037 RGD:1624291
RGD:1600115
G Fzd3 frizzled class receptor 3 JBrowse link 15 48,601,259 48,670,257 RGD:1624291
RGD:1600115
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1600115
RGD:1624291
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:10047173
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:2325303
G Otp orthopedia homeobox JBrowse link 2 24,546,393 24,554,953 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:729868
RGD:1600115
RGD:1624291
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 JBrowse link 4 7,076,710 7,108,334 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Sox10 SRY box 10 JBrowse link 7 120,393,238 120,403,523 RGD:1624291
RGD:1600115
G Sox2 SRY box 2 JBrowse link 2 121,165,137 121,167,545 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Vegfc vascular endothelial growth factor C JBrowse link 16 40,440,371 40,555,178 RGD:8554518
G Wdr62 WD repeat domain 62 JBrowse link 1 90,995,545 91,034,592 RGD:10047173
G Zfp335 zinc finger protein 335 JBrowse link 3 161,357,201 161,378,073 RGD:1600115
RGD:1624291
regulation of neuroblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Six3 SIX homeobox 3 JBrowse link 6 8,886,730 8,891,094 RGD:1624291
G Tafa1 TAFA chemokine like family member 1 JBrowse link 4 128,818,468 128,942,088 RGD:1624291
ventricular zone neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1600115
RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
Wnt signaling pathway involved in forebrain neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17895
    cell population proliferation 2081
      neural precursor cell proliferation 189
        neuroblast proliferation 70
          negative regulation of neuroblast proliferation + 9
          neuroblast division + 16
          positive regulation of neuroblast proliferation 27
          regulation of neuroblast proliferation + 39
Path 2
Term Annotations click to browse term
  biological_process 17895
    developmental process 6321
      anatomical structure development 5927
        multicellular organism development 5423
          system development 5002
            nervous system development 2549
              neurogenesis 1835
                generation of neurons 1704
                  neuroblast proliferation 70
                    negative regulation of neuroblast proliferation + 9
                    neuroblast division + 16
                    positive regulation of neuroblast proliferation 27
                    regulation of neuroblast proliferation + 39
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.