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ONTOLOGY REPORT - ANNOTATIONS


Term:endoderm development
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Accession:GO:0007492 term browser browse the term
Definition:The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.


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endoderm development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:1624291
RGD:1600115
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
G Bptf bromodomain PHD finger transcription factor JBrowse link 10 95,248,573 95,350,162 RGD:1624291
G Cfc1 cripto, FRL-1, cryptic family 1 JBrowse link 9 41,045,352 41,051,979 RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:1624291
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:1624291
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 JBrowse link 13 35,622,472 35,673,449 RGD:1624291
RGD:1600115
G Ext1 exostosin glycosyltransferase 1 JBrowse link 7 92,605,008 92,881,392 RGD:1624291
RGD:1600115
G Gdf1 growth differentiation factor 1 JBrowse link 16 20,845,580 20,860,789 RGD:1624291
G Gdf3 growth differentiation factor 3 JBrowse link 4 155,417,667 155,422,014 RGD:1624291
RGD:1600115
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:1624291
RGD:1600115
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
G Kif16b kinesin family member 16B JBrowse link 3 136,596,621 136,936,809 RGD:1624291
RGD:1600115
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
G Med12 mediator complex subunit 12 JBrowse link X 71,174,653 71,197,812 RGD:1624291
RGD:1600115
G Mixl1 Mix paired-like homeobox 1 JBrowse link 13 97,278,258 97,282,299 RGD:1624291
G Nckap1 NCK-associated protein 1 JBrowse link 3 67,725,180 67,804,680 RGD:1624291
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1600115
RGD:1624291
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Onecut1 one cut homeobox 1 JBrowse link 8 81,765,779 81,799,894 RGD:1624291
RGD:1600115
G Otx2 orthodenticle homeobox 2 JBrowse link 15 25,500,037 25,511,619 RGD:1624291
G Pax9 paired box 9 JBrowse link 6 77,607,705 77,624,453 RGD:1624291
RGD:1600115
G Pelo pelota mRNA surveillance and ribosome rescue factor JBrowse link 2 47,266,758 47,268,526 RGD:1624291
RGD:1600115
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
G Smad2 SMAD family member 2 JBrowse link 18 72,550,107 72,612,078 RGD:1624291
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1624291
RGD:1600115
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
G Sox17 SRY box 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link 10 106,698,359 106,763,639 RGD:1624291
G Wnt8a Wnt family member 8A JBrowse link 18 27,331,236 27,336,829 RGD:1624291
RGD:1600115
cell migration involved in mesendoderm migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
endoderm formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:1624291
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:1624291
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
RGD:1600115
G Mixl1 Mix paired-like homeobox 1 JBrowse link 13 97,278,258 97,282,299 RGD:1624291
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Smad2 SMAD family member 2 JBrowse link 18 72,550,107 72,612,078 RGD:1624291
RGD:1600115
G Sox17 SRY box 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
G Sox7 SRY box 7 JBrowse link 15 47,293,699 47,300,460 RGD:1624291
RGD:1600115
G Tnrc6c trinucleotide repeat containing adaptor 6C JBrowse link 10 106,698,359 106,763,639 RGD:1624291
endodermal cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col11a1 collagen type XI alpha 1 chain JBrowse link 2 216,863,423 217,056,523 RGD:1624291
RGD:1600115
G Col12a1 collagen type XII alpha 1 chain JBrowse link 8 87,042,820 87,150,701 RGD:1600115
RGD:1624291
G Col4a2 collagen type IV alpha 2 chain JBrowse link 16 83,386,388 83,522,169 RGD:1624291
RGD:1600115
G Col6a1 collagen type VI alpha 1 chain JBrowse link 20 12,657,913 12,676,370 RGD:1624291
RGD:1600115
G Col7a1 collagen type VII alpha 1 chain JBrowse link 8 117,694,441 117,726,844 RGD:1624291
G Col8a1 collagen type VIII alpha 1 chain JBrowse link 11 44,877,690 45,006,203 RGD:1624291
RGD:1600115
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:1600115
RGD:1624291
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
RGD:1600115
G Hsbp1 heat shock factor binding protein 1 JBrowse link 19 51,985,196 51,989,528 RGD:1624291
RGD:1600115
G Inhba inhibin subunit beta A JBrowse link 17 51,894,869 51,919,998 RGD:1624291
RGD:1600115
G Itga4 integrin subunit alpha 4 JBrowse link 3 66,178,745 66,265,547 RGD:1624291
RGD:1600115
G Itga5 integrin subunit alpha 5 JBrowse link 7 144,970,444 144,993,652 RGD:1624291
RGD:1600115
G Itga7 integrin subunit alpha 7 JBrowse link 7 3,355,079 3,383,886 RGD:1600115
RGD:1624291
G Itgav integrin subunit alpha V JBrowse link 3 71,113,269 71,205,958 RGD:1624291
RGD:1600115
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1624291
RGD:1600115
G Itgb5 integrin subunit beta 5 JBrowse link 11 70,056,500 70,172,164 RGD:1624291
G Lama3 laminin subunit alpha 3 JBrowse link 18 3,704,866 3,941,215 RGD:1624291
G Lamb1 laminin subunit beta 1 JBrowse link 6 50,528,796 50,596,593 RGD:1624291
RGD:1600115
G Lamb3 laminin subunit beta 3 JBrowse link 13 112,031,614 112,073,187 RGD:1624291
RGD:1600115
G Mixl1 Mix paired-like homeobox 1 JBrowse link 13 97,278,258 97,282,299 RGD:1624291
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:1624291
RGD:1600115
G Mmp15 matrix metallopeptidase 15 JBrowse link 19 10,079,881 10,101,380 RGD:1624291
RGD:1600115
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:1600115
RGD:1624291
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1600115
RGD:1624291
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1600115
RGD:1624291
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
RGD:1600115
G Setd2 SET domain containing 2, histone lysine methyltransferase JBrowse link 8 118,802,478 118,888,224 RGD:1624291
RGD:1600115
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:1624291
RGD:1600115
endodermal cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc73 cell division cycle 73 JBrowse link 13 60,403,771 60,496,511 RGD:1600115
RGD:1624291
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component JBrowse link 1 175,839,140 175,869,167 RGD:1624291
RGD:1600115
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component JBrowse link 8 82,380,906 82,405,293 RGD:1624291
RGD:1600115
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component JBrowse link 1 85,362,421 85,367,999 RGD:1624291
RGD:1600115
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291
RGD:1600115
G Rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) JBrowse link 3 111,478,350 111,537,941 RGD:1624291
endodermal cell fate determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Sox17 SRY box 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
RGD:1600115
endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:1624291
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
RGD:1600115
G Nanog Nanog homeobox JBrowse link 4 155,531,906 155,539,268 RGD:1624291
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291
G Sox2 SRY box 2 JBrowse link 2 121,165,137 121,167,545 RGD:1624291
RGD:1600115
mesendoderm development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
RGD:1600115
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:1624291
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
G Ldb1 LIM domain binding 1 JBrowse link 1 265,772,729 265,798,442 RGD:1624291
RGD:1600115
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
RGD:1600115
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
RGD:1600115
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Ssbp3 single stranded DNA binding protein 3 JBrowse link 5 126,511,339 126,649,830 RGD:1624291
RGD:1600115
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1624291
RGD:1600115
negative regulation of endodermal cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col5a1 collagen type V alpha 1 chain JBrowse link 3 6,430,180 6,581,010 RGD:1600115
RGD:1624291
G Col5a2 collagen type V alpha 2 chain JBrowse link 9 52,091,088 52,238,735 RGD:1624291
RGD:1600115
negative regulation of endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115
regulation of endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sox17 SRY box 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
RGD:1600115

Term paths to the root
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Term Annotations click to browse term
  biological_process 17941
    developmental process 6374
      anatomical structure development 5982
        tissue development 2021
          endoderm development 82
            endoderm formation + 51
            mesendoderm development + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.