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ONTOLOGY REPORT - ANNOTATIONS


Term:sex determination
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Accession:GO:0007530 term browser browse the term
Definition:Any process that establishes and transmits the specification of sexual status of an individual organism.
Synonyms:xref: Wikipedia:Sex-determination_system


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sex determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ISO
IBA
(MGI:MGI:3851651|PMID:19457926)
PMID:21873635
RGD PMID:19457926, PMID:21873635 MGI:MGI:3851651, RGD:13792537 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 ISO MGI:MGI:98660 (MGI:MGI:1196664|PMID:9486644) RGD PMID:9486644 MGI:MGI:1196664 NCBI chr  X:54,734,385...54,738,513
Ensembl chr  X:54,734,385...54,738,513
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 ISS
ISO
GO_REF:0000024
(PMID:24405868), (PMID:27378692), (PMID:27490115), (PMID:27610946), (PMID:27855412)
UniProt
RGD
PMID:24405868, PMID:27378692, PMID:27490115, PMID:27610946, PMID:27855412 GO_REF:0000024 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Sox3 SRY-box transcription factor 3 ISO (PMID:21183788)
(MGI:MGI:5000178|PMID:21183788)
RGD PMID:21183788 MGI:MGI:5000178 NCBI chr  X:144,035,162...144,037,364
Ensembl chr  X:144,035,883...144,037,294
JBrowse link
G Sry sex determining region Y ISO MGI:MGI:1352460 (MGI:MGI:1196664|PMID:9486644) RGD PMID:9486644 MGI:MGI:1196664 NCBI chr  Y:327,176...327,685
Ensembl chr  Y:327,166...329,299
JBrowse link
G Tcf21 transcription factor 21 ISO
ISS
MGI:MGI:2148207 (MGI:MGI:1347485|PMID:10572052)
GO_REF:0000024
RGD
UniProt
PMID:10572052 GO_REF:0000024, MGI:MGI:1347485 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
G Wt1 WT1 transcription factor ISO
IEA
ISS
MGI:MGI:2183642 (MGI:MGI:2149238|PMID:11509181)
GO_REF:0000107
GO_REF:0000024
(PMID:9815658)
RGD
Ensembl
UniProt
PMID:9815658, PMID:11509181 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2149238 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
female sex determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 IEA
ISO
GO_REF:0000107
(PMID:11283799)
Ensembl
RGD
PMID:11283799 GO_REF:0000107 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
female somatic sex determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxl2 forkhead box L2 ISO MGI:MGI:2182312 (MGI:MGI:3583842|PMID:15944199) RGD PMID:15944199 MGI:MGI:3583842 NCBI chr 8:107,194,492...107,197,644
Ensembl chr 8:107,194,551...107,195,675
JBrowse link
germ-line sex determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem184a transmembrane protein 184A ISO (MGI:MGI:3783844|PMID:18321981) RGD PMID:18321981 MGI:MGI:3783844 NCBI chr12:16,906,863...16,924,143
Ensembl chr12:16,912,249...16,921,426
JBrowse link
maintenance of imprinting at mating-type locus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp445 zinc finger protein 445 ISO UniProtKB:Q8C6P8 (MGI:MGI:6284037|PMID:30602440) RGD PMID:30602440 MGI:MGI:6284037 NCBI chr 8:131,885,119...131,904,303
Ensembl chr 8:131,888,047...131,899,023
JBrowse link
G Zfp57 zinc finger protein 57 ISO UniProtKB:Q8R2V3 (MGI:MGI:6284037|PMID:30602440) RGD PMID:30602440 MGI:MGI:6284037 NCBI chr20:2,014,177...2,020,488
Ensembl chr20:2,014,170...2,020,537
JBrowse link
male germ-line sex determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO MGI:MGI:1856634 (MGI:MGI:55544|PMID:6855886) RGD PMID:6855886 MGI:MGI:55544 NCBI chr 1:48,625,714...48,711,642
Ensembl chr 1:48,625,743...48,711,642
JBrowse link
G Sox9 SRY-box transcription factor 9 ISS
ISO
GO_REF:0000024
MGI:MGI:2385468|MGI:MGI:2673819|MGI:MGI:3580900 (MGI:MGI:2178704|PMID:11431689), (MGI:MGI:3611673|PMID:16207837)
UniProt
RGD
PMID:11431689, PMID:16207837 GO_REF:0000024, MGI:MGI:2178704, MGI:MGI:3611673 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
male sex determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhh desert hedgehog signaling molecule ISO MGI:MGI:1095403 (MGI:MGI:3769860|PMID:17495005) RGD PMID:17495005 MGI:MGI:3769860 NCBI chr 7:140,575,288...140,580,783
Ensembl chr 7:140,575,288...140,580,783
JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 ISO (MGI:MGI:1926717|PMID:11040213), (MGI:MGI:4420727|PMID:20007774), (MGI:MGI:4839662|PMID:20951351) RGD PMID:11040213, PMID:20007774, PMID:20951351 MGI:MGI:1926717, MGI:MGI:4420727, MGI:MGI:4839662 NCBI chr 1:243,477,403...243,582,629
Ensembl chr 1:243,477,493...243,582,629
JBrowse link
G Fgf9 fibroblast growth factor 9 ISO MGI:MGI:2135961|MGI:MGI:98371|MGI:MGI:98660|MGI:MGI:98957 (MGI:MGI:3639791|PMID:16700629) RGD PMID:16700629 MGI:MGI:3639791 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 IMP RGD PMID:7012206 RGD:9685140 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO MGI:MGI:1926486 (MGI:MGI:2680871|PMID:14628051) RGD PMID:14628051 MGI:MGI:2680871 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Insr insulin receptor ISO
IEA
MGI:MGI:1857204 (MGI:MGI:2680871|PMID:14628051)
GO_REF:0000107
RGD
Ensembl
PMID:14628051 GO_REF:0000107, MGI:MGI:2680871 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Insrr insulin receptor-related receptor ISO MGI:MGI:2653019 (MGI:MGI:2680871|PMID:14628051) RGD PMID:14628051 MGI:MGI:2680871 NCBI chr 2:187,161,817...187,181,400
Ensembl chr 2:187,162,017...187,181,395
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 IEA
ISO
GO_REF:0000107
MGI:MGI:2159321|MGI:MGI:98660 (MGI:MGI:2658696|PMID:12679814), (MGI:MGI:3580737|PMID:15944188)
Ensembl
RGD
PMID:12679814, PMID:15944188 GO_REF:0000107, MGI:MGI:2658696, MGI:MGI:3580737 NCBI chr  X:54,734,385...54,738,513
Ensembl chr  X:54,734,385...54,738,513
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 ISO (PMID:10369247) RGD PMID:10369247 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Ptgdr prostaglandin D2 receptor ISO (MGI:MGI:3609509|PMID:16185683) RGD PMID:16185683 MGI:MGI:3609509 NCBI chr15:19,195,606...19,196,508 JBrowse link
G Sf1 splicing factor 1 ISO MGI:MGI:94891 (MGI:MGI:3769860|PMID:17495005) RGD PMID:17495005 MGI:MGI:3769860 NCBI chr 1:221,735,512...221,749,216
Ensembl chr 1:221,735,517...221,749,086
JBrowse link
G Six4 SIX homeobox 4 ISO (MGI:MGI:5532793|PMID:23987514) RGD PMID:23987514 MGI:MGI:5532793 NCBI chr 6:95,984,868...95,999,709
Ensembl chr 6:95,984,868...95,998,529
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO MGI:MGI:104723|MGI:MGI:98660 (MGI:MGI:3639791|PMID:16700629) RGD PMID:16700629 MGI:MGI:3639791 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Sry sex determining region Y IEP
IBA
ISO
PMID:21873635
MGI:MGI:104723|MGI:MGI:1352460|MGI:MGI:98371 (MGI:MGI:3580945|PMID:15879091), (MGI:MGI:3639791|PMID:16700629)
RGD PMID:15879091, PMID:16700629, PMID:8430080, PMID:21873635 MGI:MGI:3580945, MGI:MGI:3639791, RGD:1598778, RGD:13792537 NCBI chr  Y:327,176...327,685
Ensembl chr  Y:327,166...329,299
JBrowse link
male somatic sex determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO
IEA
MGI:MGI:1856319 (MGI:MGI:53651|PMID:5452809)
GO_REF:0000107
RGD
Ensembl
PMID:5452809 GO_REF:0000107, MGI:MGI:53651 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
site-specific DNA replication termination at RTS1 barrier term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtfdc1 replication termination factor 2 domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:170,443,895...170,473,456
Ensembl chr 3:170,443,855...170,473,456
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    reproductive process 1785
      developmental process involved in reproduction 1178
        sex determination 26
          female sex determination + 2
          germ-line sex determination + 3
          male sex determination + 16
          mating type determination + 3
          primary sex determination + 2
          processes downstream of sex determination signal + 0
          somatic sex determination + 2
Path 2
Term Annotations click to browse term
  biological_process 20017
    reproduction 1788
      reproductive process 1785
        developmental process involved in reproduction 1178
          sex determination 26
            female sex determination + 2
            germ-line sex determination + 3
            male sex determination + 16
            mating type determination + 3
            primary sex determination + 2
            processes downstream of sex determination signal + 0
            somatic sex determination + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.