Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:4-alpha-hydroxytetrahydrobiopterin dehydratase activity
go back to main search page
Accession:GO:0008124 term browser browse the term
Definition:Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O.
Synonyms:exact_synonym: 4a-hydroxytetrahydrobiopterin dehydratase activity;   pterin-4-alpha-carbinolamine dehydratase activity;   pterin-4a-carbinolamine dehydratase activity
 related_synonym: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming];   4-alpha-hydroxy-tetrahydropterin dehydratase activity;   4a-hydroxytetrahydrobiopterin hydro-lyase activity;   4alpha-hydroxy-tetrahydropterin dehydratase activity;   pterin-4alpha-carbinolamine dehydratase activity;   tetrahydrobiopterin dehydratase activity
 xref: EC:4.2.1.96;   KEGG_REACTION:R04734;   MetaCyc:RXN-7908;   RHEA:11920;   reactome:R-HSA-71146 "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O"


show annotations for term's descendants           Sort by:
 
4-alpha-hydroxytetrahydrobiopterin dehydratase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 IDA
IBA
PMID:1465414
PMID:21873635
CAFA
GO_Central
PMID:1465414, PMID:21873635 RGD:12792994, RGD:13792537 NCBI chr20:30,689,690...30,696,465
Ensembl chr20:30,690,810...30,696,476
JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:8,929,675...8,980,712
Ensembl chr17:8,929,810...8,980,571
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    catalytic activity 6065
      lyase activity 212
        carbon-oxygen lyase activity 92
          hydro-lyase activity 71
            4-alpha-hydroxytetrahydrobiopterin dehydratase activity 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.