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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA replication
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Accession:GO:0008156 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.
Synonyms:exact_synonym: down regulation of DNA replication;   downregulation of DNA replication
 narrow_synonym: inhibition of DNA replication
 related_synonym: DNA replication inhibitor


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negative regulation of DNA replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:1624291
G Cdan1 codanin 1 JBrowse link 3 112,660,839 112,676,596 RGD:1624291
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 10 108,095,131 108,099,483 RGD:1600115
RGD:1624291
G Gmnn geminin, DNA replication inhibitor JBrowse link 17 42,302,523 42,310,783 RGD:1624291
G Gtpbp4 GTP binding protein 4 JBrowse link 17 63,111,086 63,145,618 RGD:1624291
RGD:1600115
G Hcrt hypocretin neuropeptide precursor JBrowse link 10 88,669,216 88,670,430 RGD:1600965
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:2316772
G Hus1 HUS1 checkpoint clamp component JBrowse link 14 89,194,086 89,208,825 RGD:1624291
G Inppl1 inositol polyphosphate phosphatase-like 1 JBrowse link 1 166,898,177 166,912,524 RGD:1626126
G Mapk15 mitogen-activated protein kinase 15 JBrowse link 7 117,041,287 117,061,799 RGD:632686
G Pds5a PDS5 cohesin associated factor A JBrowse link 14 44,185,445 44,282,308 RGD:1624291
RGD:1600115
G Rad17 RAD17 checkpoint clamp loader component JBrowse link 2 30,634,353 30,664,618 RGD:1624291
G Slfn13 schlafen family member 13 JBrowse link 10 70,326,157 70,343,024 RGD:1624291
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
RGD:13792537
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Tspyl2 TSPY-like 2 JBrowse link X 22,408,118 22,413,886 RGD:1624291
G Wapl WAPL cohesin release factor JBrowse link 16 11,029,325 11,108,867 RGD:1624291
negative regulation of DNA endoreduplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxo5 F-box protein 5 JBrowse link 1 42,461,277 42,467,646 RGD:1624291
negative regulation of DNA-dependent DNA replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gmnn geminin, DNA replication inhibitor JBrowse link 17 42,302,523 42,310,783 RGD:1624291
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:11557986
G Lig3 DNA ligase 3 JBrowse link 10 70,134,734 70,158,051 RGD:1624291
replication fork arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msh3 mutS homolog 3 JBrowse link 2 21,790,048 21,931,791 RGD:13792537
G Slfn13 schlafen family member 13 JBrowse link 10 70,326,157 70,343,024 RGD:1624291
G Timeless timeless circadian regulator JBrowse link 7 2,643,288 2,667,329 RGD:13792537
G Tipin timeless interacting protein JBrowse link 8 69,753,363 69,768,640 RGD:13792537
G Tipinl1 TIMELESS interacting protein like 1 JBrowse link 5 173,761 174,959 RGD:13792537
replication fork protection term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:1624291
RGD:1600115
G Donson DNA replication fork stabilization factor DONSON JBrowse link 11 31,834,608 31,847,751 RGD:1624291
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 JBrowse link 9 79,943,775 79,990,230 RGD:13792537
G Timeless timeless circadian regulator JBrowse link 7 2,643,288 2,667,329 RGD:13792537
G Tipin timeless interacting protein JBrowse link 8 69,753,363 69,768,640 RGD:13792537
RGD:1600115
G Tipinl1 TIMELESS interacting protein like 1 JBrowse link 5 173,761 174,959 RGD:13792537
G Zfp830 zinc finger protein 830 JBrowse link 10 70,118,250 70,119,714 RGD:1624291
RGD:13792537
RGD:1600115
G Zranb3 zinc finger RANBP2-type containing 3 JBrowse link 13 44,661,375 44,812,430 RGD:1624291
RGD:13792537
signal transduction involved in intra-S DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      biosynthetic process 5934
        cellular biosynthetic process 5757
          cellular macromolecule biosynthetic process 4773
            DNA replication 241
              negative regulation of DNA replication 31
                negative regulation of DNA-dependent DNA replication + 16
Path 2
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      organic substance metabolic process 10949
        macromolecule metabolic process 9418
          macromolecule biosynthetic process 4905
            cellular macromolecule biosynthetic process 4773
              DNA replication 241
                regulation of DNA replication 113
                  negative regulation of DNA replication 31
                    negative regulation of DNA-dependent DNA replication + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.