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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine metabolic process
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Accession:GO:0008291 term browser browse the term
Definition:The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
Synonyms:exact_synonym: acetylcholine metabolism


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acetylcholine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) ISO RGD PMID:16628397 RGD:1580871 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184
JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHAT choline O-acetyltransferase ISO RGD PMID:126256, PMID:334962, PMID:4008917, PMID:6854006 RGD:2301195, RGD:2301197, RGD:2301199, RGD:2301203 NCBI chr10:44,574,925...44,629,618 JBrowse link
G SLC44A4 solute carrier family 44 member 4 ISO (PMID:23651124), (PMID:28013291) UniProtKB PMID:23651124, PMID:28013291 NCBI chr 6:31,526,660...31,542,165
Ensembl chr 6:32,413,441...32,428,550
JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO (PMID:11068039)
(MGI:MGI:3044863|PMID:15173594)
PMID:10649566
UniProtKB
MGI
UniProt
PMID:10649566, PMID:11068039, PMID:15173594 MGI:MGI:3044863, RGD:68853 NCBI chr2A:93,917,086...93,944,308
Ensembl chr2A:109,017,805...109,046,860
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) ISO (PMID:1517212)
(MGI:MGI:3654414|PMID:16434405), (MGI:MGI:65815|PMID:7512968)
HGNC
MGI
RGD
PMID:126256, PMID:334962, PMID:1133098, PMID:1517212, PMID:2731551, PMID:3655326, PMID:4008917, PMID:6854006, PMID:7512968, PMID:8737018, PMID:14646156, PMID:16052514, PMID:16434405 MGI:MGI:3654414, MGI:MGI:65815, RGD:1580870, RGD:2301187, RGD:2301195, RGD:2301197, RGD:2301199, RGD:2301203, RGD:2301204, RGD:2301205, RGD:2301207, RGD:2301213 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:8888012 RGD:2302806 NCBI chr12:115,716,953...115,726,412
Ensembl chr12:119,093,952...119,105,054
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHR follicle stimulating hormone receptor ISO (MGI:MGI:3628883|PMID:12204217) MGI PMID:12204217 MGI:MGI:3628883 NCBI chr2A:49,088,450...49,287,688
Ensembl chr2A:50,008,328...50,207,258
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12524
    metabolic process 7962
      nitrogen compound metabolic process 6668
        acetylcholine metabolic process 6
          acetylcholine biosynthetic process + 3
          acetylcholine catabolic process + 1
          negative regulation of acetylcholine metabolic process + 0
          positive regulation of acetylcholine metabolic process + 1
          regulation of acetylcholine metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 12524
    biological regulation 9129
      regulation of biological quality 3472
        regulation of neurotransmitter levels 208
          neurotransmitter metabolic process 15
            acetylcholine metabolic process 6
              acetylcholine biosynthetic process + 3
              acetylcholine catabolic process + 1
              negative regulation of acetylcholine metabolic process + 0
              positive regulation of acetylcholine metabolic process + 1
              regulation of acetylcholine metabolic process + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.