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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine metabolic process
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Accession:GO:0008291 term browser browse the term
Definition:The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
Synonyms:exact_synonym: acetylcholine metabolism


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acetylcholine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase ISO RGD PMID:16628397 RGD:1580871 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHAT choline O-acetyltransferase ISO RGD PMID:126256, PMID:334962, PMID:4008917, PMID:6854006 RGD:2301195, RGD:2301197, RGD:2301199, RGD:2301203 NCBI chr28:1,480,364...1,528,858
Ensembl chr28:1,482,202...1,528,776
JBrowse link
G SLC44A4 solute carrier family 44 member 4 IEA Ensembl GO_REF:0000107 NCBI chr12:1,328,276...1,340,752
Ensembl chr12:1,328,399...1,340,778
JBrowse link
G SLC5A7 solute carrier family 5 member 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:35,879,880...35,908,203
Ensembl chr10:35,883,245...35,908,569
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase IEA Ensembl GO_REF:0000107 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:8888012 RGD:2302806 NCBI chr26:14,522,124...14,526,370
Ensembl chr26:14,500,074...14,529,354
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHR follicle stimulating hormone receptor IEA Ensembl GO_REF:0000107 NCBI chr10:50,765,591...50,938,643
Ensembl chr10:50,770,995...50,938,474
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    metabolic process 10639
      nitrogen compound metabolic process 8979
        acetylcholine metabolic process 6
          acetylcholine biosynthetic process + 3
          acetylcholine catabolic process + 1
          negative regulation of acetylcholine metabolic process + 0
          positive regulation of acetylcholine metabolic process + 1
          regulation of acetylcholine metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 16162
    biological regulation 11530
      regulation of biological quality 4009
        regulation of neurotransmitter levels 245
          neurotransmitter metabolic process 24
            acetylcholine metabolic process 6
              acetylcholine biosynthetic process + 3
              acetylcholine catabolic process + 1
              negative regulation of acetylcholine metabolic process + 0
              positive regulation of acetylcholine metabolic process + 1
              regulation of acetylcholine metabolic process + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.