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ONTOLOGY REPORT - ANNOTATIONS


Term:isoprenoid biosynthetic process
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Accession:GO:0008299 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
Synonyms:exact_synonym: isoprenoid anabolism;   isoprenoid biosynthesis;   isoprenoid formation;   isoprenoid synthesis
 narrow_synonym: polyisoprenoid anabolism;   polyisoprenoid biosynthesis;   polyisoprenoid biosynthetic process;   polyisoprenoid formation;   polyisoprenoid synthesis;   polyterpene biosynthesis;   polyterpene biosynthetic process
 alt_id: GO:0009241
 xref: MetaCyc:POLYISOPRENSYN-PWY


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isoprenoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07028137.1 RGD:1600115
G Coq2 coenzyme Q2, polyprenyltransferase JBrowse link 14 10,581,102 10,601,093 RGD:1600115
G Crppa CDP-L-ribitol pyrophosphorylase A JBrowse link 6 55,880,136 56,159,466 RGD:1600115
G Fdft1 farnesyl diphosphate farnesyl transferase 1 JBrowse link 15 46,339,248 46,367,302 RGD:1600115
G Fdps farnesyl diphosphate synthase JBrowse link 2 188,403,595 188,413,219 RGD:2316922
RGD:1600115
G Ggps1 geranylgeranyl diphosphate synthase 1 JBrowse link 17 53,956,185 53,971,039 RGD:1600115
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:2316848
RGD:13792537
RGD:2316922
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:1600115
G Idi1 isopentenyl-diphosphate delta isomerase 1 JBrowse link 17 57,976,266 57,984,036 RGD:1600115
RGD:1624291
G Idi2 isopentenyl-diphosphate delta isomerase 2 JBrowse link 17 63,107,152 63,107,469 RGD:1624291
G LOC103694120 isopentenyl-diphosphate delta-isomerase 2-like JBrowse link 17 57,814,239 57,816,277 RGD:1600115
G Mvd mevalonate diphosphate decarboxylase JBrowse link 19 55,258,910 55,268,933 RGD:1624291
G Mvk mevalonate kinase JBrowse link 12 47,904,266 47,920,457 RGD:2316851
RGD:1624291
RGD:2316922
G Pdss1 decaprenyl diphosphate synthase subunit 1 JBrowse link 17 90,033,432 90,072,506 RGD:1624291
G Pdss2 decaprenyl diphosphate synthase subunit 2 JBrowse link 20 47,966,513 48,192,747 RGD:1624291
G Pex5 peroxisomal biogenesis factor 5 JBrowse link 4 156,983,914 157,009,675 RGD:1624291
G Pmvk phosphomevalonate kinase JBrowse link 2 188,784,329 188,793,890 RGD:2316922
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:1624291
RGD:1600115
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:1624291
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 JBrowse link 1 16,910,043 16,929,465 RGD:1624291
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:2306683
G Dhrs9 dehydrogenase/reductase 9 JBrowse link 3 55,623,671 55,645,883 RGD:1624291
RGD:1600115
G Rdh16 retinol dehydrogenase 16 JBrowse link 7 71,058,150 71,072,685 RGD:1624291
dolichol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat2 acetyl-CoA acetyltransferase 2 JBrowse link 1 47,972,399 47,992,654 RGD:2326086
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit JBrowse link 20 33,557,052 33,584,011 RGD:1624291
G Srd5a3 steroid 5 alpha-reductase 3 JBrowse link 14 34,554,769 34,570,423 RGD:13792537
farnesyl diphosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fdps farnesyl diphosphate synthase JBrowse link 2 188,403,595 188,413,219 RGD:2316305
RGD:13792537
RGD:1600115
G Ggps1 geranylgeranyl diphosphate synthase 1 JBrowse link 17 53,956,185 53,971,039 RGD:1600115
farnesyl diphosphate biosynthetic process, mevalonate pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:1300058
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 JBrowse link 2 52,427,351 52,445,082 RGD:13792537
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:13792537
geranyl diphosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fdps farnesyl diphosphate synthase JBrowse link 2 188,403,595 188,413,219 RGD:1600115
G Ggps1 geranylgeranyl diphosphate synthase 1 JBrowse link 17 53,956,185 53,971,039 RGD:1600115
geranylgeranyl diphosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ggps1 geranylgeranyl diphosphate synthase 1 JBrowse link 17 53,956,185 53,971,039 RGD:1600115
isopentenyl diphosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07028157.1 RGD:13792537
G Idi1 isopentenyl-diphosphate delta isomerase 1 JBrowse link 17 57,976,266 57,984,036 RGD:13792537
G LOC102551575 isopentenyl-diphosphate delta-isomerase 2-like JBrowse link 17 57,864,652 57,866,201 RGD:13792537
G LOC291276 similar to isopentenyl diphosphate delta-isomerase type 2 JBrowse link 17 57,701,861 57,705,698 RGD:13792537
G RGD1564347 similar to isopentenyl diphosphate delta-isomerase type 2 JBrowse link 17 57,674,146 57,688,350 RGD:13792537
isopentenyl diphosphate biosynthetic process, mevalonate pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mvd mevalonate diphosphate decarboxylase JBrowse link 19 55,258,910 55,268,933 RGD:2316852
RGD:13792537
RGD:1600115
G Mvk mevalonate kinase JBrowse link 12 47,904,266 47,920,457 RGD:2316852
RGD:13792537
RGD:1600115
G Pmvk phosphomevalonate kinase JBrowse link 2 188,784,329 188,793,890 RGD:2316852
RGD:13792537
RGD:1600115
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
polyprenol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhdds dehydrodolichyl diphosphate synthase subunit JBrowse link 5 152,200,681 152,227,669 RGD:13792537
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rdh10 retinol dehydrogenase 10 JBrowse link 5 2,605,265 2,631,905 RGD:6771354
G Rdh16 retinol dehydrogenase 16 JBrowse link 7 71,058,150 71,072,685 RGD:6771354
retinoic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6771354
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:6771322
RGD:1624291
RGD:1600115
RGD:6771354
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 JBrowse link 1 127,302,920 127,337,828 RGD:6771322
RGD:1624291
RGD:1600115
RGD:6771354
G Crabp2 cellular retinoic acid binding protein 2 JBrowse link 2 187,322,416 187,326,794 RGD:6771322
G Dhrs9 dehydrogenase/reductase 9 JBrowse link 3 55,623,671 55,645,883 RGD:6771322
RGD:6771354
G Rbp1 retinol binding protein 1 JBrowse link 8 106,449,321 106,470,842 RGD:6771322
G Rdh10 retinol dehydrogenase 10 JBrowse link 5 2,605,265 2,631,905 RGD:1624291
triterpenoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lss lanosterol synthase JBrowse link 20 12,844,522 12,870,474 RGD:1600115
zeaxanthin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpe65 retinoid isomerohydrolase RPE65 JBrowse link 2 266,141,581 266,169,197 RGD:1624291
RGD:1600115
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      cellular metabolic process 10644
        cellular biosynthetic process 5814
          isoprenoid biosynthetic process 39
            apocarotenoid biosynthetic process + 0
            isopentenyl diphosphate biosynthetic process + 8
            isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate 0
            isoprenoid biosynthetic process via mevalonate + 3
            polyprenol biosynthetic process + 4
            prenol biosynthetic process 0
            terpene biosynthetic process + 0
            terpenoid biosynthetic process + 18
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      primary metabolic process 10482
        lipid metabolic process 1315
          cellular lipid metabolic process 1003
            isoprenoid metabolic process 108
              isoprenoid biosynthetic process 39
                apocarotenoid biosynthetic process + 0
                isopentenyl diphosphate biosynthetic process + 8
                isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate 0
                isoprenoid biosynthetic process via mevalonate + 3
                polyprenol biosynthetic process + 4
                prenol biosynthetic process 0
                terpene biosynthetic process + 0
                terpenoid biosynthetic process + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.