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ONTOLOGY REPORT - ANNOTATIONS


Term:determination of adult lifespan
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Accession:GO:0008340 term browser browse the term
Definition:The control of viability and duration in the adult phase of the life-cycle.


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determination of adult lifespan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 NOT ISO (MGI:MGI:5800654|PMID:27010503) RGD PMID:27010503 MGI:MGI:5800654 NCBI chr16:19,799,943...19,826,057
Ensembl chr16:19,800,463...19,803,796
JBrowse link
G Atm ATM serine/threonine kinase ISO MGI:MGI:3605986|MGI:MGI:894697 (MGI:MGI:3836659|PMID:19061978) RGD PMID:19061978 MGI:MGI:3836659 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atn1 atrophin 1 ISO MGI:MGI:4360645 (MGI:MGI:4359552|PMID:19681162) RGD PMID:19681162 MGI:MGI:4359552 NCBI chr 4:157,267,394...157,281,199
Ensembl chr 4:157,267,901...157,274,755
Ensembl chr 9:157,267,901...157,274,755
JBrowse link
G Bbc3 Bcl-2 binding component 3 ISO UniProtKB:P02340 (MGI:MGI:4944151|PMID:20818388) RGD PMID:20818388 MGI:MGI:4944151 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Cfh complement factor H ISO (MGI:MGI:5883383|PMID:28057640) RGD PMID:28057640 MGI:MGI:5883383 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cgas cyclic GMP-AMP synthase ISO MGI:MGI:1328317 (MGI:MGI:5699498|PMID:26371324) RGD PMID:26371324 MGI:MGI:5699498 NCBI chr 8:85,789,515...85,804,008
Ensembl chr 8:85,789,763...85,803,433
JBrowse link
G Coq7 coenzyme Q7, hydroxylase ISO
IBA
MGI:MGI:2157003 (MGI:MGI:4359329|PMID:19478076)
PMID:21873635
RGD PMID:19478076, PMID:21873635 MGI:MGI:4359329, RGD:13792537 NCBI chr 1:188,176,060...188,190,874
Ensembl chr 1:188,174,874...188,190,860
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease ISO MGI:MGI:3043589 (MGI:MGI:3041918|PMID:15082767) RGD PMID:15082767 MGI:MGI:3041918 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Gba glucosylceramidase beta ISO (MGI:MGI:3795074|PMID:18346921) RGD PMID:18346921 MGI:MGI:3795074 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Ghrhr growth hormone releasing hormone receptor ISO MGI:MGI:1856425 (MGI:MGI:2135699|PMID:11371619) RGD PMID:11371619 MGI:MGI:2135699 NCBI chr 4:85,587,321...85,602,389
Ensembl chr 4:85,588,595...85,601,666
JBrowse link
G Hdac9 histone deacetylase 9 ISO MGI:MGI:1890508 (MGI:MGI:5139938|PMID:21746928) RGD PMID:21746928 MGI:MGI:5139938 NCBI chr 6:53,487,367...54,358,694
Ensembl chr 6:53,488,883...54,059,119
JBrowse link
G Htt huntingtin ISO MGI:MGI:2177757|MGI:MGI:2177767|MGI:MGI:2177768 (MGI:MGI:1926691|PMID:11062468), (MGI:MGI:1929816|PMID:11152661) RGD PMID:11062468, PMID:11152661 MGI:MGI:1926691, MGI:MGI:1929816 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase ISO MGI:MGI:1890508 (MGI:MGI:5500993|PMID:23686339) RGD PMID:23686339 MGI:MGI:5500993 NCBI chr 5:169,475,270...169,482,031
Ensembl chr 5:169,475,270...169,482,030
JBrowse link
G Ide insulin degrading enzyme ISO (PMID:18448515) RGD PMID:18448515 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO
IEA
MGI:MGI:2386884 (MGI:MGI:1266928|PMID:9620849)
GO_REF:0000107
RGD
Ensembl
PMID:9620849 GO_REF:0000107, MGI:MGI:1266928 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771
JBrowse link
G Lep leptin ISO MGI:MGI:1328317 (MGI:MGI:5829115|PMID:28069950) RGD PMID:28069950 MGI:MGI:5829115 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:19692353) RGD PMID:19692353 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Msh2 mutS homolog 2 ISO
IEA
MGI:MGI:1858055 (MGI:MGI:1351797|PMID:10545954)
GO_REF:0000107
RGD
Ensembl
PMID:10545954 GO_REF:0000107, MGI:MGI:1351797 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msh6 mutS homolog 6 ISO MGI:MGI:1858014|MGI:MGI:2151803 (MGI:MGI:1100204|PMID:9390556), (MGI:MGI:1351797|PMID:10545954) RGD PMID:9390556, PMID:10545954 MGI:MGI:1100204, MGI:MGI:1351797 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499
JBrowse link
G Pou1f1 POU class 1 homeobox 1 ISO MGI:MGI:1856024|MGI:MGI:1856025 (MGI:MGI:2135699|PMID:11371619) RGD PMID:11371619 MGI:MGI:2135699 NCBI chr11:2,645,659...2,662,581
Ensembl chr11:2,645,865...2,662,579
JBrowse link
G Prdm2 PR/SET domain 2 ISO
IEA
MGI:MGI:2388354 (MGI:MGI:2149923|PMID:11544182)
GO_REF:0000107
RGD
Ensembl
PMID:11544182 GO_REF:0000107, MGI:MGI:2149923 NCBI chr 5:161,769,587...161,879,150
Ensembl chr 5:161,770,653...161,879,133
JBrowse link
G Rad54b RAD54 homolog B ISO MGI:MGI:107202|MGI:MGI:894697 (MGI:MGI:3836659|PMID:19061978) RGD PMID:19061978 MGI:MGI:3836659 NCBI chr 5:25,140,531...25,214,469
Ensembl chr 5:25,146,949...25,214,376
JBrowse link
G Rad54l RAD54 like ISO MGI:MGI:107202|MGI:MGI:3605986 (MGI:MGI:3836659|PMID:19061978) RGD PMID:19061978 MGI:MGI:3836659 NCBI chr 5:134,948,511...134,978,125
Ensembl chr 5:134,948,512...134,978,125
JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 ISO MGI:MGI:1890508 (MGI:MGI:5913114|PMID:23695662) RGD PMID:23695662 MGI:MGI:5913114 NCBI chr  X:146,532,002...146,533,538 JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 ISO MGI:MGI:3707684 (MGI:MGI:3703120|PMID:17079272) RGD PMID:17079272 MGI:MGI:3703120 NCBI chr13:34,610,689...34,671,617
Ensembl chr13:34,610,684...34,670,124
JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:4944151|PMID:20818388) RGD PMID:20818388 MGI:MGI:4944151 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trex1 three prime repair exonuclease 1 ISO MGI:MGI:104663|MGI:MGI:2442261|MGI:MGI:3052754 (MGI:MGI:3052278|PMID:15254239), (MGI:MGI:5699498|PMID:26371324), (MGI:MGI:5829115|PMID:28069950) RGD PMID:15254239, PMID:26371324, PMID:28069950 MGI:MGI:3052278, MGI:MGI:5699498, MGI:MGI:5829115 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 ISO MGI:MGI:1099440|MGI:MGI:1888594|MGI:MGI:1931221|MGI:MGI:2180033 (MGI:MGI:2178865|PMID:11923874), (MGI:MGI:3583382|PMID:15980864), (MGI:MGI:3789238|PMID:16079796), (MGI:MGI:3797328|PMID:18443001), (MGI:MGI:5139938|PMID:21746928), (MGI:MGI:5500993|PMID:23686339), (MGI:MGI:5824440|PMID:27799555), (MGI:MGI:5913114|PMID:23695662) RGD PMID:11923874, PMID:15980864, PMID:16079796, PMID:18443001, PMID:21746928, PMID:23686339, PMID:23695662, PMID:27799555 MGI:MGI:2178865, MGI:MGI:3583382, MGI:MGI:3789238, MGI:MGI:3797328, MGI:MGI:5139938, MGI:MGI:5500993, MGI:MGI:5824440, MGI:MGI:5913114 NCBI chr 5:139,982,404...140,015,541
Ensembl chr 5:139,983,680...140,015,541
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    multicellular organismal process 9055
      determination of adult lifespan 28
        insulin receptor signaling pathway involved in determination of adult lifespan + 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          multicellular organism aging 54
            determination of adult lifespan 28
              insulin receptor signaling pathway involved in determination of adult lifespan + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.