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ONTOLOGY REPORT - ANNOTATIONS


Term:GDP-mannose 4,6-dehydratase activity
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Accession:GO:0008446 term browser browse the term
Definition:Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O.
Synonyms:related_synonym: GDP-D-mannose 4,6-dehydratase activity;   GDP-D-mannose dehydratase activity;   GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming);   GDP-mannose 4,6-hydro-lyase activity;   GDPmannose 4,6-dehydratase activity;   Gmd;   guanosine 5'-diphosphate-D-mannose oxidoreductase activity;   guanosine diphosphomannose 4,6-dehydratase activity;   guanosine diphosphomannose oxidoreductase activity
 xref: EC:4.2.1.47;   KEGG_REACTION:R00888;   MetaCyc:GDPMANDEHYDRA-RXN;   RHEA:23820;   reactome:R-HSA-6787632 "GMDS dehydrates GDP-Man to GDP-DHDMan"


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GDP-mannose 4,6-dehydratase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gmds GDP-mannose 4, 6-dehydratase ISS
ISO
IBA
GO_REF:0000024
UniProtKB:Q8K3X3 (PMID:9525924), (PMID:9603974)
PMID:21873635
UniProt
RGD
PMID:9525924, PMID:9603974, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr17:33,408,722...33,938,086
Ensembl chr17:33,408,722...33,938,085
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  molecular_function 20457
    catalytic activity 6065
      lyase activity 212
        carbon-oxygen lyase activity 92
          hydro-lyase activity 71
            GDP-mannose 4,6-dehydratase activity 1
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