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ONTOLOGY REPORT - ANNOTATIONS


Term:protein-tyrosine sulfotransferase activity
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Accession:GO:0008476 term browser browse the term
Definition:Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.
Synonyms:exact_synonym: protein-tyrosine sulphotransferase activity
 related_synonym: 3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity;   tyrosylprotein sulfotransferase activity
 xref: EC:2.8.2.20;   MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN;   RHEA:16801;   Reactome:R-HSA-9668023 "TPST1,2 transfer SO4(2-) from PAPS to FVIII";   Reactome:R-HSA-9668148 "F8 variant is not sulfonated at Y1699";   reactome:R-HSA-8954262 "TPST1,2 transfer SO4(2-) from PAPS to PODXL2"


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protein-tyrosine sulfotransferase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpst1 tyrosylprotein sulfotransferase 1 ISO
ISS
IEA
IBA
(PMID:9501187)
GO_REF:0000024
MGI:MGI:2183366 (MGI:MGI:1275820|PMID:9501187), (MGI:MGI:3697050|PMID:17046811)
GO_REF:0000003
PMID:21873635
RGD
UniProt
PMID:9501187, PMID:17046811, PMID:21873635 GO_REF:0000003, GO_REF:0000024, MGI:MGI:1275820, MGI:MGI:3697050, RGD:13792537 NCBI chr12:30,045,753...30,112,377
Ensembl chr12:30,045,751...30,106,893
JBrowse link
G Tpst2 tyrosylprotein sulfotransferase 2 ISO
IBA
ISS
MGI:MGI:3512111 (MGI:MGI:3697050|PMID:17046811)
PMID:21873635
(PMID:23481380), (PMID:9733778)
GO_REF:0000024
RGD
UniProt
PMID:9733778, PMID:17046811, PMID:23481380, PMID:21873635 GO_REF:0000024, MGI:MGI:3697050, RGD:13792537 NCBI chr12:50,343,076...50,383,534
Ensembl chr12:50,343,086...50,383,496
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20467
    catalytic activity 6067
      catalytic activity, acting on a protein 2312
        protein-tyrosine sulfotransferase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20467
    catalytic activity 6067
      transferase activity 2353
        transferase activity, transferring sulfur-containing groups 78
          sulfotransferase activity 59
            protein-tyrosine sulfotransferase activity 2
paths to the root

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