Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:epsilon DNA polymerase complex
go back to main search page
Accession:GO:0008622 term browser browse the term
Definition:A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.


show annotations for term's descendants       view all columns           Sort by:
 
epsilon DNA polymerase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07027368.1 RGD:13792537
G AABR07052692.1 RGD:13792537
G LOC100362333 DNA-directed DNA polymerase epsilon 3 JBrowse link 7 118,816,053 118,816,725 RGD:1600115
RGD:13792537
G Pole DNA polymerase epsilon, catalytic subunit JBrowse link 12 52,403,533 52,452,075 RGD:13792537
RGD:1624291
G Pole2 DNA polymerase epsilon 2, accessory subunit JBrowse link 6 91,494,348 91,532,355 RGD:13792537
RGD:1624291
G Pole3 DNA polymerase epsilon 3, accessory subunit JBrowse link 5 78,380,813 78,384,047 RGD:1624291
RGD:13792537
RGD:1600115
G Pole4 DNA polymerase epsilon 4, accessory subunit JBrowse link 4 113,491,644 113,497,455 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19951
    intracellular 13934
      DNA polymerase complex 23
        epsilon DNA polymerase complex 7
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        intracellular organelle 12137
          intracellular membrane-bounded organelle 10066
            nucleus 6843
              nuclear lumen 4008
                nuclear chromosome 658
                  epsilon DNA polymerase complex 7
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.