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ONTOLOGY REPORT - ANNOTATIONS


Term:intrinsic apoptotic signaling pathway in response to osmotic stress
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Accession:GO:0008627 term browser browse the term
Definition:A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.
Synonyms:related_synonym: induction of apoptosis by ionic changes


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intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Scn2a sodium voltage-gated channel alpha subunit 2 JBrowse link 3 51,687,910 51,822,008 RGD:1624291
RGD:1600115
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:1624291
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:1624291
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
G Ybx3 Y box binding protein 3 JBrowse link 4 165,606,819 165,630,041 RGD:1624291
RGD:1600115
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:1624291
RGD:1600115
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    response to stimulus 10490
      response to stress 3960
        response to osmotic stress 127
          cellular response to osmotic stress 63
            intrinsic apoptotic signaling pathway in response to osmotic stress 9
              intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
              negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 6
              positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 1
              regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 7
Path 2
Term Annotations click to browse term
  biological_process 19578
    biological regulation 13539
      regulation of biological process 12843
        regulation of cellular process 12334
          signal transduction 6929
            apoptotic signaling pathway 629
              intrinsic apoptotic signaling pathway 301
                intrinsic apoptotic signaling pathway in response to osmotic stress 9
                  intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
                  negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 6
                  positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 1
                  regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.