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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
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Accession:GO:0008635 term browser browse the term
Definition:Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.
Synonyms:exact_synonym: caspase activation via cytochrome c
 narrow_synonym: activation of caspase activity by cytochrome c


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activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:1624291
RGD:13792537
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
RGD:1600115
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1624291
RGD:1600115
G Cops5 COP9 signalosome subunit 5 JBrowse link 5 8,876,090 8,894,345 RGD:1624291
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:1624291
G Diablo diablo, IAP-binding mitochondrial protein JBrowse link 12 38,490,230 38,503,344 RGD:1624291
RGD:13792537
G LOC100360940 diablo-like JBrowse link 5 147,607,350 147,608,936 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    cellular process 16266
      positive regulation of cellular process 5522
        positive regulation of cell death 736
          positive regulation of programmed cell death 669
            positive regulation of apoptotic process 664
              positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 130
                activation of cysteine-type endopeptidase activity involved in apoptotic process 80
                  activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c 8
Path 2
Term Annotations click to browse term
  biological_process 18166
    metabolic process 10845
      organic substance metabolic process 10283
        macromolecule metabolic process 8818
          protein metabolic process 5590
            cellular protein metabolic process 4932
              regulation of cellular protein metabolic process 2658
                positive regulation of cellular protein metabolic process 1620
                  positive regulation of proteolysis 357
                    positive regulation of peptidase activity 185
                      positive regulation of endopeptidase activity 168
                        positive regulation of cysteine-type endopeptidase activity 147
                          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 130
                            activation of cysteine-type endopeptidase activity involved in apoptotic process 80
                              activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.