Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:phospholipase A1 activity
go back to main search page
Accession:GO:0008970 term browser browse the term
Definition:Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
Synonyms:exact_synonym: phosphatidylcholine 1-acylhydrolase activity
 xref: EC:3.1.1.32;   MetaCyc:PHOSPHOLIPASE-A1-RXN;   reactome:R-HSA-1482827 "PC is hydrolyzed to 2-acyl LPC by PLA2G4C";   reactome:R-HSA-1482828 "PE is hydrolyzed to 2-acyl LPE by PLA2[4]";   reactome:R-HSA-1482847 "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)";   reactome:R-HSA-1482862 "PC is hydrolysed to 2-acyl LPC by PLA2[7]";   reactome:R-HSA-1482892 "PE is hydrolyzed to 2-acyl LPE by PLA2G4C";   reactome:R-HSA-1482920 "PG is hydrolyzed to 2-acyl LPG by PLA2[14]";   reactome:R-HSA-1482932 "PI is hydrolyzed to 2-acyl LPI by PLA2[13]";   reactome:R-HSA-5694485 "ABHD3 hydrolyses LPC(14:0) to 1AGPC"


show annotations for term's descendants       view all columns           Sort by:
 
phospholipase A1 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd3 abhydrolase domain containing 3, phospholipase JBrowse link 18 1,892,413 1,946,840 RGD:1624291
RGD:13792537
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308772
G Lipg lipase G, endothelial type JBrowse link 18 70,903,528 70,924,434 RGD:1624291
G Pla1a phospholipase A1 member A JBrowse link 11 64,882,024 64,919,714 RGD:1624291
G Plaat1 phospholipase A and acyltransferase 1 JBrowse link 11 75,125,951 75,145,868 RGD:1624291
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:12790655
RGD:1624291
G Plaat5 phospholipase A and acyltransferase 5 JBrowse link 1 222,907,159 222,937,643 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19527
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 781
          carboxylic ester hydrolase activity 156
            phospholipase A1 activity 7
Path 2
Term Annotations click to browse term
  molecular_function 19527
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 781
          lipase activity 120
            phospholipase activity 92
              phospholipase A1 activity 7
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.