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ONTOLOGY REPORT - ANNOTATIONS


Term:glutamine family amino acid metabolic process
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Accession:GO:0009064 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
Synonyms:exact_synonym: glutamine family amino acid metabolism


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ammonia assimilation cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:1624291
RGD:1600115
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:632694
RGD:2301547
arginine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:632221
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:631755
RGD:13792537
RGD:1624291
RGD:12859071
RGD:1600115
G Nags N-acetylglutamate synthase JBrowse link 10 90,084,607 90,089,693 RGD:13792537
arginine biosynthetic process via ornithine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:1600115
RGD:13792537
G Otc ornithine carbamoyltransferase JBrowse link X 13,524,804 13,601,074 RGD:13792537
arginine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddah1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 2 251,634,368 251,766,009 RGD:1624291
G Ddah2 dimethylarginine dimethylaminohydrolase 2 JBrowse link 20 5,049,260 5,052,573 RGD:1600115
G Fah fumarylacetoacetate hydrolase JBrowse link 1 146,713,663 146,736,339 RGD:1624291
RGD:1600115
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:8553334
RGD:13792537
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:1624291
RGD:13792537
RGD:1600115
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:1600115
RGD:13792537
RGD:1624291
arginine catabolic process to glutamate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:13792537
arginine catabolic process to ornithine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:8693655
RGD:13792537
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1358311
RGD:13792537
RGD:8693655
arginine catabolic process to proline via ornithine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:13792537
arginine deiminase pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Padi3 peptidyl arginine deiminase 3 JBrowse link 5 159,309,000 159,336,429 RGD:69926
arginine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:2300098
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1582129
RGD:1600115
G Ddah1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 2 251,634,368 251,766,009 RGD:1625578
RGD:13792537
G Ddah2 dimethylarginine dimethylaminohydrolase 2 JBrowse link 20 5,049,260 5,052,573 RGD:1625578
RGD:13792537
G Slc39a8 solute carrier family 39 member 8 JBrowse link 2 241,028,851 241,092,584 RGD:1600115
RGD:1624291
asparagine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspg asparaginase JBrowse link 6 136,682,279 136,701,673 RGD:13792537
asparagine catabolic process via L-aspartate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asrgl1 asparaginase and isoaspartyl peptidase 1 JBrowse link 1 225,309,737 225,329,743 RGD:1299508
RGD:13792537
RGD:1624291
glutamate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gls glutaminase JBrowse link 9 54,212,622 54,284,879 RGD:1600115
RGD:13792537
RGD:1624291
G Gls2 glutaminase 2 JBrowse link 7 2,605,679 2,621,853 RGD:13792537
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:1624291
G Slc25a12 solute carrier family 25 member 12 JBrowse link 3 57,881,951 57,998,214 RGD:13628741
glutamate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:1601355
RGD:13792537
RGD:1624291
glutamate catabolic process to 2-oxoglutarate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:1624291
RGD:13504861
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:1624291
RGD:13504861
glutamate catabolic process to aspartate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:1624291
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:1624291
glutamate catabolic process via 2-oxoglutarate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adhfe1 alcohol dehydrogenase, iron containing, 1 JBrowse link 5 9,403,194 9,429,783 RGD:1600115
RGD:1624291
glutamate decarboxylation to succinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:1625237
glutamate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadat aminoadipate aminotransferase JBrowse link 16 32,832,001 32,868,680 RGD:1624291
RGD:1600115
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1624291
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 JBrowse link 17 42,133,076 42,159,413 RGD:1624291
RGD:1600115
G Dglucy D-glutamate cyclase JBrowse link 6 124,786,164 124,870,244 RGD:1624291
RGD:13792537
G Fpgs folylpolyglutamate synthase JBrowse link 3 11,717,667 11,729,694 RGD:1624291
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:1600115
RGD:1624291
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:1600115
RGD:1624291
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:1624291
RGD:1600115
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:2301548
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:1600115
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:1600115
G Mthfs methenyltetrahydrofolate synthetase JBrowse link 8 96,564,877 96,614,386 RGD:1624291
G Nags N-acetylglutamate synthase JBrowse link 10 90,084,607 90,089,693 RGD:1624291
RGD:13792537
G Tat tyrosine aminotransferase JBrowse link 19 41,675,639 41,686,195 RGD:1624291
RGD:1600115
glutamine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:2301548
RGD:13792537
RGD:2301547
G Lgsn lengsin, lens protein with glutamine synthetase domain JBrowse link 9 37,458,603 37,490,117 RGD:13792537
glutamine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gls glutaminase JBrowse link 9 54,212,622 54,284,879 RGD:728510
RGD:13792537
RGD:1624291
RGD:1600115
G Gls2 glutaminase 2 JBrowse link 7 2,605,679 2,621,853 RGD:13792537
G Ppat phosphoribosyl pyrophosphate amidotransferase JBrowse link 14 33,580,541 33,614,919 RGD:633710
glutamine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adssl1 adenylosuccinate synthase like 1 JBrowse link 6 137,184,818 137,206,694 RGD:5135508
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:1600115
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link 6 26,657,507 26,680,459 RGD:5132588
RGD:13792537
RGD:10755425
G Cps1 carbamoyl-phosphate synthase 1 JBrowse link 9 74,113,437 74,236,274 RGD:13792537
G Ctps1 CTP synthase 1 JBrowse link 5 139,475,934 139,505,065 RGD:1600115
G Ctps2 CTP synthase 2 JBrowse link X 33,383,087 33,522,852 RGD:1600115
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 JBrowse link 4 118,852,046 118,901,583 RGD:1600115
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 JBrowse link 10 35,279,237 35,325,506 RGD:1600115
G Gls glutaminase JBrowse link 9 54,212,622 54,284,879 RGD:1600115
G Gls2 glutaminase 2 JBrowse link 7 2,605,679 2,621,853 RGD:1600115
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:1624291
RGD:1600115
G Gmps guanine monophosphate synthase JBrowse link 2 154,555,967 154,590,662 RGD:1600115
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1624291
RGD:1600115
G Nit2 nitrilase family, member 2 JBrowse link 11 45,462,345 45,473,107 RGD:1624291
RGD:13792537
G Pfas phosphoribosylformylglycinamidine synthase JBrowse link 10 55,571,881 55,593,384 RGD:1599004
G Phgdh phosphoglycerate dehydrogenase JBrowse link 2 200,484,245 200,513,564 RGD:1624291
G Sirt4 sirtuin 4 JBrowse link 12 46,862,358 46,876,593 RGD:1624291
histidine catabolic process to glutamate and formamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amdhd1 amidohydrolase domain containing 1 JBrowse link 7 34,362,635 34,406,282 RGD:1600115
G Ftcd formimidoyltransferase cyclodeaminase JBrowse link 20 12,806,957 12,820,466 RGD:1600115
G Hal histidine ammonia lyase JBrowse link 7 34,326,087 34,356,413 RGD:1600115
histidine catabolic process to glutamate and formate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ftcd formimidoyltransferase cyclodeaminase JBrowse link 20 12,806,957 12,820,466 RGD:1600115
G Hal histidine ammonia lyase JBrowse link 7 34,326,087 34,356,413 RGD:1600115
L-proline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1600115
G LOC108348083 delta-1-pyrroline-5-carboxylate synthase JBrowse link 1 259,057,407 259,089,727 RGD:1600115
G Noxred1 NADP-dependent oxidoreductase domain containing 1 JBrowse link 6 111,243,232 111,271,107 RGD:13792537
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:1600115
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1600115
RGD:13792537
G Pycr2 pyrroline-5-carboxylate reductase 2 JBrowse link 13 99,184,624 99,188,418 RGD:1600115
RGD:13792537
G Pycr3 pyrroline-5-carboxylate reductase 3 JBrowse link 7 116,949,882 116,955,150 RGD:1600115
RGD:13792537
RGD:1624291
negative regulation of arginine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
negative regulation of glutamate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atcay ATCAY kinesin light chain interacting caytaxin JBrowse link 7 11,356,017 11,379,782 RGD:1624291
RGD:1600115
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1624291
RGD:1600115
positive regulation of glutamate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1624291
proline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1624291
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1624291
G Pycr2 pyrroline-5-carboxylate reductase 2 JBrowse link 13 99,184,624 99,188,418 RGD:1624291
RGD:1600115
proline catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dao D-amino-acid oxidase JBrowse link 12 48,353,691 48,373,647 RGD:1600115
RGD:13792537
RGD:1624291
G Prodh2 proline dehydrogenase 2 JBrowse link 1 88,955,125 88,968,501 RGD:1600115
proline catabolic process to glutamate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 JBrowse link 5 158,090,238 158,115,725 RGD:1600115
G Iffo2 intermediate filament family orphan 2 JBrowse link 5 158,042,587 158,083,311 RGD:1600115
G Prodh1 proline dehydrogenase 1 JBrowse link 11 87,058,478 87,075,785 RGD:13792537
G Prodh2 proline dehydrogenase 2 JBrowse link 1 88,955,125 88,968,501 RGD:13792537
G Tas1r2 taste 1 receptor member 2 JBrowse link 5 158,119,894 158,135,733 RGD:1600115
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agmat agmatinase JBrowse link 5 160,306,754 160,321,951 RGD:13792537
regulation of arginine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
regulation of arginine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fh fumarate hydratase JBrowse link 13 93,651,486 93,677,371 RGD:1600115
RGD:1624291
G Slc7a7 solute carrier family 7 member 7 JBrowse link 15 33,013,346 33,059,733 RGD:1624291
RGD:13792537
regulation of glutamate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:6484536
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:1624291
regulation of glutamine family amino acid metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt4 sirtuin 4 JBrowse link 12 46,862,358 46,876,593 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      primary metabolic process 10563
        cellular amino acid metabolic process 267
          alpha-amino acid metabolic process 193
            glutamine family amino acid metabolic process 75
              arginine metabolic process + 20
              glutamate metabolic process + 34
              glutamine family amino acid biosynthetic process + 18
              glutamine family amino acid catabolic process + 27
              glutamine metabolic process + 22
              proline metabolic process + 13
              regulation of glutamine family amino acid metabolic process + 9
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      cellular metabolic process 10737
        organic acid metabolic process 1053
          oxoacid metabolic process 1026
            carboxylic acid metabolic process 979
              cellular amino acid metabolic process 267
                alpha-amino acid metabolic process 193
                  glutamine family amino acid metabolic process 75
                    arginine metabolic process + 20
                    glutamate metabolic process + 34
                    glutamine family amino acid biosynthetic process + 18
                    glutamine family amino acid catabolic process + 27
                    glutamine metabolic process + 22
                    proline metabolic process + 13
                    regulation of glutamine family amino acid metabolic process + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.