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ONTOLOGY REPORT - ANNOTATIONS


Term:aspartate family amino acid metabolic process
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Accession:GO:0009066 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid metabolism


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asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) IDA
IBA
ISO
PMID:21873635
(PMID:2573597)
RGD PMID:2573597, PMID:2887559, PMID:21873635 RGD:2316002, RGD:13792537 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:52,988,042...53,009,054
Ensembl chr 9:53,004,499...53,009,054
JBrowse link
asparagine catabolic process via L-aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asrgl1 asparaginase and isoaspartyl peptidase 1 IDA
IBA
ISO
PMID:12753071
PMID:21873635
(PMID:19839645)
RGD PMID:19839645, PMID:12753071, PMID:21873635 RGD:1299508, RGD:13792537 NCBI chr 1:225,309,737...225,329,743
Ensembl chr 1:225,309,246...225,329,770
JBrowse link
asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspg asparaginase IDA PMID:9575212 UniProt PMID:9575212 RGD:1299414 NCBI chr 6:136,682,279...136,701,673
Ensembl chr 6:136,682,126...136,701,628
JBrowse link
G Nit2 nitrilase family, member 2 ISO
IBA
(PMID:22674578)
PMID:21873635
RGD PMID:22674578, PMID:21873635 RGD:13792537 NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 ISO
IBA
(MGI:MGI:53641|PMID:4193185)
PMID:21873635
RGD PMID:4193185, PMID:21873635 MGI:MGI:53641, RGD:13792537 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:69,022,756...69,035,507
Ensembl chr16:69,022,784...69,028,179
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO (MGI:MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:MGI:53641 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddo D-aspartate oxidase ISO
IBA
(PMID:9163533)
PMID:21873635
RGD PMID:9163533, PMID:21873635 RGD:13792537 NCBI chr20:48,739,812...48,758,958
Ensembl chr20:48,739,639...48,758,905
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO (PMID:2241899) RGD PMID:2241899 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO
IBA
(PMID:2567216)
PMID:21873635
RGD PMID:2567216, PMID:21873635 RGD:13792537 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adss adenylosuccinate synthase IDA RGD PMID:71897 RGD:5135533 NCBI chr13:95,913,426...95,943,761
Ensembl chr13:95,913,426...95,943,761
JBrowse link
G Adssl1 adenylosuccinate synthase like 1 IDA RGD PMID:3759987 RGD:5135303 NCBI chr 6:137,184,818...137,206,694
Ensembl chr 6:137,184,820...137,206,693
JBrowse link
G Ass1 argininosuccinate synthase 1 ISO (PMID:7977368) RGD PMID:7977368 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Ddo D-aspartate oxidase ISO
IBA
MGI:MGI:3625623 (MGI:MGI:3617951|PMID:16525061)
PMID:21873635
RGD PMID:16525061, PMID:21873635 MGI:MGI:3617951, RGD:13792537 NCBI chr20:48,739,812...48,758,958
Ensembl chr20:48,739,639...48,758,905
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IDA
ISS
GO_REF:0000024 UniProt PMID:2837211 GO_REF:0000024, RGD:2289377 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 IMP
ISS
GO_REF:0000024 UniProt PMID:12686151 GO_REF:0000024, RGD:2289396 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 ISO (MGI:MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:MGI:53641 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO (MGI:MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:MGI:53641 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 IEA
ISO
GO_REF:0000107
(PMID:10934207)
Ensembl
RGD
PMID:10934207 GO_REF:0000107 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ISO (MGI:MGI:6202004|PMID:16447251) RGD PMID:16447251 MGI:MGI:6202004 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
L-asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 ISO (PMID:11960987) RGD PMID:11960987 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
L-lysine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase ISO (MGI:MGI:1350812|PMID:10567240) RGD PMID:10567240 MGI:MGI:1350812 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pipox pipecolic acid and sarcosine oxidase ISO
IBA
(PMID:10642506)
PMID:21873635
RGD PMID:10642506, PMID:21873635 RGD:13792537 NCBI chr10:64,951,986...64,964,865
Ensembl chr10:64,952,119...64,964,862
JBrowse link
L-lysine catabolic process to acetyl-CoA via saccharopine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:32,832,001...32,868,680
Ensembl chr16:32,832,061...32,868,702
JBrowse link
G Aass aminoadipate-semialdehyde synthase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase ISO
IEA
(PMID:18230605)
GO_REF:0000107
RGD
Ensembl
PMID:18230605 GO_REF:0000107 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 ISO
IEA
(PMID:18230605)
GO_REF:0000107
RGD
Ensembl
PMID:18230605 GO_REF:0000107 NCBI chr 2:23,272,320...23,289,266
Ensembl chr 2:23,272,328...23,289,266
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:15938715)
UniProt
RGD
PMID:15938715 GO_REF:0000024, GO_REF:0000041 NCBI chr 6:47,940,211...47,947,173
Ensembl chr 6:47,940,183...47,947,230
JBrowse link
G Apip APAF1 interacting protein IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(PMID:22837397), (PMID:23285211)
UniProt
RGD
PMID:22837397, PMID:23285211, PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483
JBrowse link
G Enoph1 enolase-phosphatase 1 IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:15843022)
UniProt
RGD
PMID:15843022, PMID:21873635 GO_REF:0000024, GO_REF:0000041, RGD:13792537 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806
JBrowse link
G Mtap methylthioadenosine phosphorylase IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:107,711,077...107,777,530
Ensembl chr 5:107,711,077...107,777,530
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483
JBrowse link
G Enoph1 enolase-phosphatase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806
JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:1,432,757...1,450,175
Ensembl chr 8:1,439,340...1,450,138
JBrowse link
G Aass aminoadipate-semialdehyde synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase IDA
ISO
(MGI:MGI:3510291|PMID:15217352) RGD PMID:15217352, PMID:15845641 MGI:MGI:3510291, RGD:1359026 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO
IBA
MGI:MGI:2385823 (MGI:MGI:3510291|PMID:15217352)
PMID:21873635
RGD PMID:15217352, PMID:21873635 MGI:MGI:3510291, RGD:13792537 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IDA
IEA
ISO
GO_REF:0000107
(PMID:23825108)
MGI:MGI:2180496 (MGI:MGI:1930456|PMID:11158293)
Ensembl
RGD
PMID:11158293, PMID:23825108, PMID:15845641, PMID:11730351 GO_REF:0000107, MGI:MGI:1930456, RGD:1359026, RGD:1601423 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO
IBA
(PMID:11466310)
PMID:21873635
(MGI:MGI:3710265|PMID:17369066)
RGD PMID:11466310, PMID:17369066, PMID:21873635 MGI:MGI:3710265, RGD:13792537 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015
JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:10677294)
Ensembl
UniProt
RGD
PMID:10677294 GO_REF:0000024, GO_REF:0000107 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:47,940,211...47,947,173
Ensembl chr 6:47,940,183...47,947,230
JBrowse link
G Gnmt glycine N-methyltransferase ISO MGI:MGI:3842652 (MGI:MGI:3842675|PMID:17937387) RGD PMID:17937387 MGI:MGI:3842675 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (MGI:MGI:5621260|PMID:23190757) RGD PMID:23190757 MGI:MGI:5621260 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO UniProtKB:P53128 (PMID:10551815) RGD PMID:10551815 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IMP RGD PMID:21121936 RGD:7207080 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT ISO (MGI:MGI:3690523|PMID:17034760) RGD PMID:17034760 MGI:MGI:3690523 NCBI chr 4:98,976,559...98,997,187
Ensembl chr 4:98,976,550...98,995,590
JBrowse link
threonine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcat glycine C-acetyltransferase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:120,263,068...120,269,365
Ensembl chr 7:120,263,054...120,269,451
JBrowse link
G LOC688286 similar to threonine aldolase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:106,877,585...106,883,706
Ensembl chr10:106,878,085...106,883,423
JBrowse link
G Sds serine dehydratase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Sdsl serine dehydratase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,636,994...41,647,205
Ensembl chr12:41,636,994...41,647,205
JBrowse link
G Tdh L-threonine dehydrogenase ISO
IBA
(MGI:MGI:5292271|PMID:21896756), (MGI:MGI:5905531|PMID:26492815)
PMID:21873635
RGD PMID:21896756, PMID:26492815, PMID:21873635 MGI:MGI:5292271, MGI:MGI:5905531, RGD:13792537 NCBI chr15:46,667,926...46,682,752
Ensembl chr15:46,667,926...46,681,467
JBrowse link
threonine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh phosphoglycerate dehydrogenase ISO MGI:MGI:3769591 (MGI:MGI:3835979|PMID:19114063) RGD PMID:19114063 MGI:MGI:3835979 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Sds serine dehydratase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Sdsl serine dehydratase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,636,994...41,647,205
Ensembl chr12:41,636,994...41,647,205
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      primary metabolic process 10941
        cellular amino acid metabolic process 276
          alpha-amino acid metabolic process 201
            aspartate family amino acid metabolic process 41
              asparagine metabolic process + 6
              aspartate family amino acid biosynthetic process + 22
              aspartate family amino acid catabolic process + 14
              aspartate metabolic process + 7
              hydroxylysine metabolic process + 2
              lysine metabolic process + 5
              methionine metabolic process + 14
              threonine metabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      cellular metabolic process 11085
        organic acid metabolic process 1095
          oxoacid metabolic process 1066
            carboxylic acid metabolic process 1009
              cellular amino acid metabolic process 276
                alpha-amino acid metabolic process 201
                  aspartate family amino acid metabolic process 41
                    asparagine metabolic process + 6
                    aspartate family amino acid biosynthetic process + 22
                    aspartate family amino acid catabolic process + 14
                    aspartate metabolic process + 7
                    hydroxylysine metabolic process + 2
                    lysine metabolic process + 5
                    methionine metabolic process + 14
                    threonine metabolic process + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.