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ONTOLOGY REPORT - ANNOTATIONS


Term:branched-chain amino acid catabolic process
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Accession:GO:0009083 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
Synonyms:exact_synonym: branched chain family amino acid breakdown;   branched chain family amino acid catabolic process;   branched chain family amino acid catabolism;   branched chain family amino acid degradation


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branched-chain amino acid catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:1624291
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:1582175
RGD:1624291
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha JBrowse link 1 82,423,291 82,452,094 RGD:631719
RGD:13792537
RGD:1600115
RGD:1624291
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta JBrowse link 8 91,464,229 91,656,134 RGD:1624291
RGD:13792537
RGD:1600115
G Bckdk branched chain ketoacid dehydrogenase kinase JBrowse link 1 199,351,628 199,356,299 RGD:68918
RGD:68712
G Slc25a44 solute carrier family 25, member 44 JBrowse link 2 187,772,013 187,786,829 RGD:1624291
isoleucine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:1582175
RGD:1600115
RGD:1624291
leucine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Auh AU RNA binding methylglutaconyl-CoA hydratase JBrowse link 17 12,310,178 12,405,224 RGD:1600115
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase JBrowse link 5 154,294,841 154,308,582 RGD:13792537
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 JBrowse link 8 83,069,837 83,204,778 RGD:13792537
G Ivd isovaleryl-CoA dehydrogenase JBrowse link 3 110,669,355 110,689,789 RGD:1600115
RGD:8554099
G Mccc1 methylcrotonoyl-CoA carboxylase 1 JBrowse link 2 122,550,777 122,690,540 RGD:1600115
G Mccc2 methylcrotonoyl-CoA carboxylase 2 JBrowse link 2 30,175,017 30,246,028 RGD:1600115
RGD:13792537
valine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 JBrowse link 6 108,146,552 108,167,185 RGD:1599052
RGD:13792537
RGD:1600115
RGD:1624291
G Hibadh 3-hydroxyisobutyrate dehydrogenase JBrowse link 4 82,604,369 82,702,429 RGD:1600115
RGD:13792537
RGD:1624291
G Hibch 3-hydroxyisobutyryl-CoA hydrolase JBrowse link 9 53,446,185 53,526,727 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19337
    metabolic process 11555
      primary metabolic process 10411
        cellular amino acid metabolic process 266
          branched-chain amino acid metabolic process 17
            branched-chain amino acid catabolic process 16
              branched-chain amino acid catabolic process to alcohol via Ehrlich pathway 0
              branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway 0
              isoleucine catabolic process 2
              leucine catabolic process + 6
              valine catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 19337
    metabolic process 11555
      organic substance metabolic process 10949
        organic acid metabolic process 1030
          oxoacid metabolic process 1004
            carboxylic acid metabolic process 959
              carboxylic acid catabolic process 229
                cellular amino acid catabolic process 104
                  branched-chain amino acid catabolic process 16
                    branched-chain amino acid catabolic process to alcohol via Ehrlich pathway 0
                    branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway 0
                    isoleucine catabolic process 2
                    leucine catabolic process + 6
                    valine catabolic process + 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.