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ONTOLOGY REPORT - ANNOTATIONS


Term:cyclic nucleotide biosynthetic process
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Accession:GO:0009190 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
Synonyms:exact_synonym: cyclic nucleotide anabolism;   cyclic nucleotide biosynthesis;   cyclic nucleotide formation;   cyclic nucleotide synthesis


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cAMP biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:14985420, PMID:21873635 RGD:2312640, RGD:13792537 NCBI chr14:87,311,970...87,429,880
Ensembl chr14:87,312,203...87,421,659
JBrowse link
G Adcy10 adenylate cyclase 10 IDA
ISO
IMP
(PMID:12609998), (PMID:15659711) RGD PMID:12609998, PMID:15659711, PMID:9874775, PMID:7225326, PMID:16627466, PMID:16964251 RGD:1299450, RGD:2313177, RGD:2313173, RGD:2313171 NCBI chr13:83,701,952...83,787,010
Ensembl chr13:83,721,300...83,787,018
JBrowse link
G Adcy2 adenylate cyclase 2 IDA
IEA
PMID:10427002
GO_REF:0000002
PMID:18164588
GOC PMID:11738086, PMID:10427002, PMID:18164588, PMID:12711600 GO_REF:0000002, RGD:2312641, RGD:10400857, RGD:8553431, RGD:2312674 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
JBrowse link
G Adcy3 adenylate cyclase 3 IDA
IBA
ISO
IEA
PMID:21873635
(MGI:MGI:1889935|PMID:11055432)
GO_REF:0000107
PMID:24363043
RGD
Ensembl
PMID:11055432, PMID:12711600, PMID:21873635, PMID:24363043 GO_REF:0000107, MGI:MGI:1889935, RGD:2312674, RGD:13792537, RGD:10400870 NCBI chr 6:28,570,941...28,648,848
Ensembl chr 6:28,571,351...28,650,148
JBrowse link
G Adcy4 adenylate cyclase 4 IDA
IEA
GO_REF:0000043
PMID:8900209
UniProt PMID:11738086, PMID:8900209, PMID:12711600 GO_REF:0000043, RGD:2312641, RGD:8554340, RGD:2312674 NCBI chr15:34,453,917...34,469,779
Ensembl chr15:34,453,915...34,469,746
JBrowse link
G Adcy5 adenylate cyclase 5 IDA
IBA
ISO
IEA
PMID:21873635
(PMID:15385642), (PMID:24700542), (PMID:24740569)
GO_REF:0000107
RGD
Ensembl
PMID:15385642, PMID:24700542, PMID:24740569, PMID:11738086, PMID:21873635, PMID:10894801, PMID:12711600 GO_REF:0000107, RGD:2312641, RGD:13792537, RGD:2315006, RGD:2312674 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adcy6 adenylate cyclase 6 IDA
IBA
IEA
ISO
IMP
PMID:21873635
GO_REF:0000043
(PMID:17916776), (PMID:18403039)
(MGI:MGI:4457984|PMID:20466003)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17916776, PMID:18403039, PMID:20466003, PMID:15961389, PMID:21873635, PMID:10894801, PMID:15579502, PMID:12711600, PMID:10866989, PMID:18971210, PMID:11738086 GO_REF:0000043, GO_REF:0000107, MGI:MGI:4457984, RGD:1598749, RGD:13792537, RGD:2315006, RGD:2313211, RGD:2312674, RGD:2312678, RGD:2312654, RGD:2312641 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Adcy7 adenylate cyclase 7 IDA
ISO
(PMID:11113152), (PMID:17760784) RGD PMID:11113152, PMID:17760784, PMID:12711600 RGD:2312674 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
JBrowse link
G Adcy8 adenylate cyclase 8 IMP
IBA
IEA
IDA
PMID:21873635
GO_REF:0000043
UniProt PMID:16741924, PMID:21873635, PMID:19305019, PMID:19444869 GO_REF:0000043, RGD:2312769, RGD:13792537, RGD:7241269, RGD:2312785 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Adcy9 adenylate cyclase 9 IMP
ISO
(MGI:MGI:76465|PMID:7575502), (MGI:MGI:80863|PMID:8662814)
(PMID:10987815), (PMID:9628827)
RGD PMID:7575502, PMID:8662814, PMID:9628827, PMID:10987815, PMID:19444869 MGI:MGI:76465, MGI:MGI:80863, RGD:2312785 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600
JBrowse link
cGMP biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO
IEA
MGI:MGI:3640802 (MGI:MGI:3640061|PMID:16614755)
GO_REF:0000107
(PMID:23505436)
RGD
Ensembl
PMID:16614755, PMID:23505436 GO_REF:0000107, MGI:MGI:3640061 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:408,001...899,851
Ensembl chr 8:408,001...899,974
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 ISO (PMID:23505436) RGD PMID:23505436 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 IEA GO_REF:0000002
GO_REF:0000043
InterPro
UniProt
GO_REF:0000002, GO_REF:0000043 NCBI chr15:45,479,662...45,550,285
Ensembl chr15:45,479,658...45,550,285
JBrowse link
G Gucy2c guanylate cyclase 2C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:170,659,993...170,740,274
Ensembl chr 4:170,659,998...170,740,274
JBrowse link
G Gucy2d guanylate cyclase 2D, retinal ISO
IBA
IEA
(MGI:MGI:5049799|PMID:21598940)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:21598940, PMID:21873635 GO_REF:0000107, MGI:MGI:5049799, RGD:13792537 NCBI chr10:55,835,695...55,851,235
Ensembl chr10:55,835,695...55,851,235
JBrowse link
G Gucy2e guanylate cyclase 2E IDA
IBA
PMID:11580282
PMID:21873635
UniProt
GO_Central
PMID:11580282, PMID:21873635 RGD:15023466, RGD:13792537 NCBI chr 1:163,398,891...163,433,594
Ensembl chr 1:163,398,891...163,433,593
JBrowse link
G Gucy2f guanylate cyclase 2F IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:113,372,240...113,474,210
Ensembl chr  X:113,372,240...113,474,164
JBrowse link
G Gucy2g guanylate cyclase 2G IEA
IBA
GO_REF:0000043
PMID:21873635
UniProt PMID:21873635 GO_REF:0000043, RGD:13792537 NCBI chr 1:276,187,243...276,228,574
Ensembl chr 1:276,187,242...276,228,574
JBrowse link
G Nppa natriuretic peptide A ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777, PMID:21873635 RGD:13792537 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777, PMID:21873635 RGD:13792537 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nppc natriuretic peptide C ISO
IBA
(PMID:1672777)
PMID:21873635
(MGI:MGI:2177134|PMID:11259675)
RGD PMID:1672777, PMID:11259675, PMID:21873635 MGI:MGI:2177134, RGD:13792537 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777, PMID:21873635 RGD:13792537 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Npr2 natriuretic peptide receptor 2 ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777, PMID:21873635 RGD:13792537 NCBI chr 5:59,128,186...59,147,321
Ensembl chr 5:59,128,315...59,147,255
JBrowse link
cyclic purine nucleotide metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd2 adenosine monophosphate deaminase 2 ISO
ISS
(PMID:23911318)
GO_REF:0000024
RGD
UniProt
PMID:23911318 GO_REF:0000024 NCBI chr 2:210,861,624...210,874,348
Ensembl chr 2:210,861,625...210,874,304
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      organic substance metabolic process 11639
        organophosphate metabolic process 971
          nucleoside phosphate metabolic process 510
            nucleotide metabolic process 503
              nucleotide biosynthetic process 247
                cyclic nucleotide biosynthetic process 25
                  cyclic purine nucleotide metabolic process + 25
Path 2
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      cellular metabolic process 11067
        cellular aromatic compound metabolic process 5709
          nucleobase-containing compound metabolic process 5483
            nucleobase-containing small molecule metabolic process 590
              nucleoside phosphate metabolic process 510
                nucleotide metabolic process 503
                  nucleotide biosynthetic process 247
                    cyclic nucleotide biosynthetic process 25
                      cyclic purine nucleotide metabolic process + 25
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.