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ONTOLOGY REPORT - ANNOTATIONS


Term:amine metabolic process
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Accession:GO:0009308 term browser browse the term
Definition:The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
Synonyms:exact_synonym: amine metabolism


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amine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC123346.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:89,236,258...89,311,138 JBrowse link
G Aoc1 amine oxidase, copper containing 1 IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO
IBA
ISS
(PMID:9653080)
PMID:21873635
RGD PMID:9653080, PMID:21873635, PMID:9653080 RGD:13792537, RGD:8554068 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO MGI:2182307 (MGI:3703667|PMID:17052995) RGD PMID:17052995 MGI:3703667 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Doxl1 diamine oxidase-like protein 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:78,563,625...78,567,241
Ensembl chr 4:78,563,625...78,567,241
JBrowse link
G Doxl2 diamine oxidase-like protein 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:78,618,743...78,622,525
Ensembl chr 4:78,618,737...78,622,523
JBrowse link
G Inmt indolethylamine N-methyltransferase ISO (PMID:10552930) RGD PMID:10552930 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Svs1 seminal vesicle secretory protein 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:78,639,672...78,644,570
Ensembl chr 4:78,639,672...78,644,570
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO (PMID:23474851) RGD PMID:23474851 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
benzylpenicillin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 IMP RGD PMID:19255943 RGD:11081014 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:17194738 RGD:5131263 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362
JBrowse link
G Ddc dopa decarboxylase TAS
IEA
GO_REF:0000043 UniProt PMID:12047348 GO_REF:0000043, RGD:727571 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Hdc histidine decarboxylase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Th tyrosine hydroxylase IDA RGD PMID:20025246 RGD:4139888 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
catecholamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11559542), (PMID:15645182), (PMID:21846718)
UniProt
RGD
PMID:11559542, PMID:15645182, PMID:21846718, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing ISS
ISO
IBA
GO_REF:0000024
(MGI:3799635|PMID:18794526)
PMID:21873635
UniProt
RGD
PMID:18794526, PMID:21873635 GO_REF:0000024, MGI:3799635, RGD:13792537 NCBI chr 1:166,985,468...166,989,681
Ensembl chr 1:166,986,013...166,988,062
JBrowse link
G Maoa monoamine oxidase A NAS RGD PMID:12388421 RGD:629546 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:1856098 (MGI:54307|PMID:17511) RGD PMID:17511 MGI:54307 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Dbh dopamine beta-hydroxylase IC RGD PMID:11521740 RGD:1625401 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Ddc dopa decarboxylase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Mtpn myotrophin IEP RGD PMID:12051753 RGD:625450 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 IDA RGD PMID:6959650 RGD:2301075 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1d1 sulfotransferase family 1D, member 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:22,107,418...22,126,011
Ensembl chr14:22,091,777...22,126,021
JBrowse link
cellular biogenic amine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mecp2 methyl CpG binding protein 2 ISO MGI:2137311 (MGI:3607765|PMID:15975715) RGD PMID:15975715 MGI:3607765 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
choline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase TAS
ISO
IEA
(PMID:10102904)
GO_REF:0000107
RGD
Ensembl
PMID:10102904, PMID:1710985 GO_REF:0000107, RGD:632576 NCBI chr 2:23,289,376...23,370,360
Ensembl chr 2:23,289,374...23,370,477
JBrowse link
G Sardh sarcosine dehydrogenase TAS
NAS
PMID:9839943 RGD
UniProt
PMID:9839943, PMID:9839943 RGD:634034, RGD:634034 NCBI chr 3:5,737,203...5,802,153
Ensembl chr 3:5,737,200...5,802,129
JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:20097214 RGD:6903884 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:20097214 RGD:6903884 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IEP RGD PMID:12438507 RGD:704388 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:19818757 RGD:5143981 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Dao D-amino-acid oxidase IEA
ISO
GO_REF:0000107
(PMID:17303072)
Ensembl
RGD
PMID:17303072 GO_REF:0000107 NCBI chr12:48,353,691...48,373,647
Ensembl chr12:48,354,196...48,365,784
JBrowse link
G Ddc dopa decarboxylase IDA
IEA
GO_REF:0000041 UniProt PMID:12703659 GO_REF:0000041, RGD:4139893 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO (PMID:16338639) RGD PMID:16338639 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO MGI:3027995 (MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:3046856 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IEA
ISO
GO_REF:0000107
MGI:2429971 (MGI:1203924|PMID:9608532), (MGI:3767764|PMID:16782508)
Ensembl
RGD
PMID:9608532, PMID:16782508 GO_REF:0000107, MGI:1203924, MGI:3767764 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:2386303 (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Snca synuclein alpha ISO MGI:1888382 (MGI:1352916|PMID:10707987) RGD PMID:10707987 MGI:1352916 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISS
ISO
GO_REF:0000024
(MGI:3622848|PMID:16257223)
UniProt
RGD
PMID:16257223 GO_REF:0000024, MGI:3622848 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase IDA
ISO
IBA
IMP
MGI:1860450 (MGI:2386819|PMID:9520487), (MGI:72094|PMID:7715703), (MGI:77787|PMID:7592982)
PMID:21873635
PMID:11943812
RGD PMID:7592982, PMID:7715703, PMID:9520487, PMID:2427363, PMID:21873635, PMID:11943812, PMID:19584816 MGI:2386819, MGI:72094, MGI:77787, RGD:1580046, RGD:13792537, RGD:5129111, RGD:5130972 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Dbh dopamine beta-hydroxylase IEA
ISO
IBA
ISS
GO_REF:0000107
MGI:1857556 (MGI:1332340|PMID:10051631), (MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
PMID:21873635
(PMID:3443096), (PMID:7961964)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:3443096, PMID:7715704, PMID:7961964, PMID:10051631, PMID:27148966, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:1332340, MGI:5787847, MGI:72180, RGD:13792537 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Maoa monoamine oxidase A IEA
ISO
GO_REF:0000107
(MGI:2386819|PMID:9520487)
Ensembl
RGD
PMID:9520487 GO_REF:0000107, MGI:2386819 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:2386303 (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:1856098|MGI:1856466 (MGI:50550|PMID:1752214), (MGI:65000|PMID:8174230) RGD PMID:1752214, PMID:8174230 MGI:50550, MGI:65000, MGI:71923 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Comt catechol-O-methyltransferase IBA
ISO
PMID:21873635
MGI:2178542|MGI:4830700 (MGI:4830461|PMID:19930170), (MGI:5510279|PMID:23863468)
RGD PMID:19930170, PMID:23863468, PMID:21873635 MGI:4830461, MGI:5510279, RGD:13792537 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:10945868 RGD:1599723 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Ddc dopa decarboxylase TAS RGD PMID:7567987 RGD:727686 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Drd2 dopamine receptor D2 ISO (MGI:68905|PMID:7925842) RGD PMID:7925842 MGI:68905 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEA
ISO
GO_REF:0000107
MGI:1928285 (MGI:2384280|PMID:11160454)
Ensembl
RGD
PMID:11160454 GO_REF:0000107, MGI:2384280 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO MGI:1857299 (MGI:1321418|PMID:9886073), (MGI:65825|PMID:7509865), (MGI:65928|PMID:1432691) RGD PMID:1432691, PMID:7509865, PMID:9886073 MGI:1321418, MGI:65825, MGI:65928 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:166,985,468...166,989,681
Ensembl chr 1:166,986,013...166,988,062
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 ISO MGI:3527173 (MGI:6150107|PMID:28327638) RGD PMID:28327638 MGI:6150107 NCBI chr 2:46,372,488...46,476,162
Ensembl chr 2:46,372,518...46,476,203
JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:15544851 RGD:1580153 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 ISO MGI:2429971 (MGI:3529728|PMID:12385813) RGD PMID:12385813 MGI:3529728 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase NOT ISO MGI:2678247 (MGI:2675710|PMID:12915482)
MGI:3055212 (MGI:3525458|PMID:15684050)
RGD PMID:12915482, PMID:15684050 MGI:2675710, MGI:3525458 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Snca synuclein alpha ISO MGI:1889011 (MGI:3057254|PMID:15465911) RGD PMID:15465911 MGI:3057254 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncaip synuclein, alpha interacting protein ISO
ISS
(PMID:14506261)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:14506261 GO_REF:0000024 NCBI chr18:47,739,284...47,877,679
Ensembl chr18:47,739,140...47,877,676
JBrowse link
G Sncb synuclein, beta IEA
ISO
GO_REF:0000107
MGI:1277151 (MGI:3057254|PMID:15465911)
Ensembl
RGD
PMID:15465911 GO_REF:0000107, MGI:3057254 NCBI chr17:10,384,472...10,392,776
Ensembl chr17:10,384,511...10,392,843
JBrowse link
G Spr sepiapterin reductase ISO MGI:3757641 (MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:3722569 NCBI chr 4:116,912,343...116,916,073
Ensembl chr 4:116,912,351...116,916,236
JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnmt phenylethanolamine-N-methyltransferase TAS
IEA
IDA
IC
GO_REF:0000041 UniProt PMID:11514309, PMID:7914070, PMID:7503429 GO_REF:0000041, RGD:628457, RGD:4139902, RGD:4139901 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
epinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:1856098|MGI:1856466 (MGI:50550|PMID:1752214) RGD PMID:1752214 MGI:50550, MGI:71923 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
ethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chka choline kinase alpha IDA RGD PMID:1577786 RGD:61551 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 ISS
ISO
IEA
GO_REF:0000024
(MGI:3793397|PMID:18227059)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18227059 GO_REF:0000024, GO_REF:0000107, MGI:3793397 NCBI chr 1:188,367,550...188,407,125
Ensembl chr 1:188,394,814...188,407,132
JBrowse link
histamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase IEA
ISO
IBA
GO_REF:0000041
MGI:2182618 (MGI:2138019|PMID:11478947)
PMID:21873635
(PMID:22767596)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:11478947, PMID:22767596, PMID:21873635 GO_REF:0000041, GO_REF:0000107, MGI:2138019, RGD:13792537 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 ISO (PMID:10318872) RGD PMID:10318872 NCBI chr 3:72,395,194...72,401,254
Ensembl chr 3:72,395,218...72,401,318
JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase ISO
ISS
(PMID:26206890)
GO_REF:0000024
RGD
UniProt
PMID:26206890 GO_REF:0000024 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
histamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase IDA RGD PMID:4449071, PMID:9525922, PMID:7075603, PMID:5898 RGD:2303726, RGD:2303735, RGD:2303728, RGD:2303727 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hnmt histamine N-methyltransferase ISO (PMID:23505051) RGD PMID:23505051 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Trh thyrotropin releasing hormone IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:17760865, PMID:21873635 RGD:7241067, RGD:13792537 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
N-acylethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B ISO (MGI:3695251|PMID:16818490) RGD PMID:16818490 MGI:3695251 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:5295534|PMID:21801852), (MGI:5790171|PMID:25596343)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21801852, PMID:25596343 GO_REF:0000024, GO_REF:0000107, MGI:5295534, MGI:5790171 NCBI chr 1:188,367,550...188,407,125
Ensembl chr 1:188,394,814...188,407,132
JBrowse link
G Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 IEA
ISO
ISS
IBA
GO_REF:0000107
(MGI:5790171|PMID:25596343), (MGI:6104349|PMID:27637550)
GO_REF:0000024
(PMID:25596343), (PMID:27637550)
PMID:21873635
Ensembl
RGD
UniProt
PMID:25596343, PMID:27637550, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:5790171, MGI:6104349, RGD:13792537 NCBI chr10:74,334,972...74,376,332
Ensembl chr10:74,334,975...74,376,270
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 ISO (PMID:27637550)
(MGI:6104349|PMID:27637550)
RGD PMID:27637550 MGI:6104349 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Naaa N-acylethanolamine acid amidase ISS
IDA
ISO
GO_REF:0000024
PMID:22860206
(PMID:15655246), (PMID:30301806)
UniProt
RGD
PMID:15655246, PMID:30301806, PMID:22860206 GO_REF:0000024, RGD:39458030 NCBI chr14:17,283,262...17,302,364
Ensembl chr14:17,283,124...17,302,366
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D IBA
ISO
PMID:21873635
MGI:3695401 (MGI:3044670|PMID:14634025), (MGI:3695251|PMID:16818490)
RGD PMID:14634025, PMID:16818490, PMID:21873635 MGI:3044670, MGI:3695251, RGD:13792537 NCBI chr 4:9,965,323...10,004,650
Ensembl chr 4:9,966,891...10,002,247
JBrowse link
negative regulation of arginine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
negative regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:1856098 (MGI:54307|PMID:17511) RGD PMID:17511 MGI:54307 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15190105 RGD:2289786 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:17018023 RGD:1625003 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Itgam integrin subunit alpha M ISO (MGI:3814938|PMID:18981141) RGD PMID:18981141 MGI:3814938 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Snca synuclein alpha IMP PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atcay ATCAY kinesin light chain interacting caytaxin ISO
ISS
(PMID:16899818)
GO_REF:0000024
RGD
UniProt
PMID:16899818 GO_REF:0000024 NCBI chr 7:11,356,017...11,379,782
Ensembl chr 7:11,356,118...11,380,913
JBrowse link
nor-spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:1856097|MGI:1856098 (MGI:53801|PMID:4405722), (MGI:53940|PMID:4858102) RGD PMID:4405722, PMID:4858102 MGI:53801, MGI:53940 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Dbh dopamine beta-hydroxylase TAS
ISO
IBA
ISS
IEA
IMP
MGI:1857556 (MGI:1203930|PMID:9603211), (MGI:1332340|PMID:10051631), (MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
PMID:21873635
GO_REF:0000024
(PMID:27148966)
GO_REF:0000041
RGD
UniProt
PMID:7715704, PMID:9603211, PMID:10051631, PMID:27148966, PMID:11914591, PMID:21873635, PMID:10573542 GO_REF:0000024, GO_REF:0000041, MGI:1203930, MGI:1332340, MGI:5787847, MGI:72180, RGD:727567, RGD:13792537, RGD:1625403 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Gata3 GATA binding protein 3 ISS
ISO
GO_REF:0000024
MGI:2153826 (MGI:1859081|PMID:10835639)
UniProt
RGD
PMID:10835639 GO_REF:0000024, MGI:1859081 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Insm1 INSM transcriptional repressor 1 ISO (MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:3772428 NCBI chr 3:140,427,961...140,430,467 JBrowse link
G Kl Klotho IMP RGD PMID:20086041 RGD:10403068 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
norepinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B IDA RGD PMID:10424772 RGD:8548769 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Atp7a ATPase copper transporting alpha ISO MGI:1856102|MGI:1856466 (MGI:53851|PMID:4147174) RGD PMID:4147174 MGI:53851, MGI:71923 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Epas1 endothelial PAS domain protein 1 IEA
ISO
GO_REF:0000107
MGI:1861921 (MGI:1313089|PMID:9808618)
Ensembl
RGD
PMID:9808618 GO_REF:0000107, MGI:1313089 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO MGI:2429638 (MGI:2157257|PMID:11784869) RGD PMID:11784869 MGI:2157257 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IDA RGD PMID:3945626 RGD:5130757 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO MGI:3050230 (MGI:3047192|PMID:15249681) RGD PMID:15249681 MGI:3047192 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Rnf180 ring finger protein 180 IBA
ISO
PMID:21873635
(MGI:5505713|PMID:23926250)
RGD PMID:23926250, PMID:21873635 MGI:5505713, RGD:13792537 NCBI chr 2:35,718,100...35,892,578
Ensembl chr 2:35,718,889...35,870,578
JBrowse link
G Rtl4 retrotransposon Gag like 4 ISO MGI:5789261 (MGI:5749620|PMID:26402067) RGD PMID:26402067 MGI:5749620 NCBI chr  X:115,908,999...116,402,406
Ensembl chr  X:116,399,611...116,400,516
JBrowse link
G Spr sepiapterin reductase ISO MGI:3757641 (MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:3722569 NCBI chr 4:116,912,343...116,916,073
Ensembl chr 4:116,912,351...116,916,236
JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IMP RGD PMID:11521740 RGD:1625401 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
phenylethylamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Maoa monoamine oxidase A IDA
IMP
Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741, PMID:11754741 RGD:1600709, RGD:1600709 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Azin2 antizyme inhibitor 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
JBrowse link
G LOC100912604 spermidine synthase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,588,818...14,591,980
Ensembl chr 3:14,588,870...14,591,974
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:11,752,127...11,754,587
Ensembl chr 7:11,752,412...11,754,508
JBrowse link
G Odc1 ornithine decarboxylase 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 ISO (PMID:15283699) RGD PMID:15283699 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT ISO (PMID:15283699) RGD PMID:15283699 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
G Srm spermidine synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
polyamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
(MGI:2663545|PMID:12660232)
(PMID:12477380)
RGD PMID:12477380, PMID:12660232, PMID:15541750 MGI:2663545, RGD:7244190 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:15541750 RGD:7244190 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Smox spermine oxidase ISO (PMID:12477380) RGD PMID:12477380 NCBI chr 3:124,068,796...124,103,726
Ensembl chr 3:124,068,865...124,102,240
JBrowse link
polyamine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 ISS
ISO
GO_REF:0000024
(PMID:28516954)
UniProt
RGD
PMID:28516954 GO_REF:0000024 NCBI chr 7:130,102,335...130,109,036
Ensembl chr 7:130,102,347...130,107,437
JBrowse link
G Hdac6 histone deacetylase 6 NOT ISO (PMID:28516954) RGD PMID:28516954 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
polyamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:71,216,011...71,229,788
Ensembl chr 8:71,216,178...71,228,713
JBrowse link
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:11172929 RGD:1599544 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 IDA RGD PMID:8888012 RGD:2302806 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IEA
ISO
GO_REF:0000107
(MGI:5306122|PMID:21757002)
Ensembl
RGD
PMID:21757002 GO_REF:0000107, MGI:5306122 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Park7 Parkinsonism associated deglycase ISO
IEA
ISS
(PMID:19703902)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
ParkinsonsUK-UCL
PMID:19703902 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Vps35 VPS35 retromer complex component ISO (MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:5694519 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11239920 RGD:10047061 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO MGI:3027995 (MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:3046856 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO (PMID:8643611) RGD PMID:8643611 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Npy neuropeptide Y IDA RGD PMID:19579268 RGD:10448966 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
positive regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 ISO (MGI:5306122|PMID:21757002) RGD PMID:21757002 MGI:5306122 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
positive regulation of homocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15779086 RGD:2289784 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO
IEA
ISS
(PMID:16731528)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
ParkinsonsUK-UCL
PMID:16731528 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 IEA
ISO
GO_REF:0000107
(MGI:4413411|PMID:19008477)
Ensembl
RGD
PMID:19008477 GO_REF:0000107, MGI:4413411 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
putrescine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362, PMID:1415709 RGD:1578320, RGD:7242912 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Paox polyamine oxidase ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:160,306,754...160,321,951
Ensembl chr 5:160,306,727...160,321,066
JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Azin2 antizyme inhibitor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
JBrowse link
G Odc1 ornithine decarboxylase 1 IEA
ISO
IBA
ISS
GO_REF:0000041
(MGI:5574513|PMID:24967154)
PMID:21873635
GO_REF:0000024
UniProt
RGD
PMID:24967154, PMID:21873635 GO_REF:0000024, GO_REF:0000041, MGI:5574513, RGD:13792537 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G RGD1562036 similar to ornithine decarboxylase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:148,432,213...148,444,188
Ensembl chr 5:148,433,086...148,444,188
JBrowse link
putrescine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669, PMID:16354669 RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
putrescine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aoc1 amine oxidase, copper containing 1 ISO
ISS
(PMID:8144586)
GO_REF:0000024
RGD
UniProt
PMID:8144586 GO_REF:0000024 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor ISO MGI:88392 (MGI:3628883|PMID:12204217) RGD PMID:12204217 MGI:3628883 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
regulation of arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:4830440|PMID:19284480) RGD PMID:19284480 MGI:4830440 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
regulation of arginine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fh fumarate hydratase ISS
ISO
GO_REF:0000024
(MGI:5496931|PMID:23643539)
UniProt
RGD
PMID:23643539 GO_REF:0000024, MGI:5496931 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Slc7a7 solute carrier family 7 member 7 IBA
ISO
PMID:21873635
MGI:3530880 (MGI:3760035|PMID:17376816)
RGD PMID:17376816, PMID:21873635 MGI:3760035, RGD:13792537 NCBI chr15:33,013,346...33,059,733
Ensembl chr15:33,013,504...33,051,129
JBrowse link
regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vhl von Hippel-Lindau tumor suppressor IMP RGD PMID:11912140 RGD:619592 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
regulation of cellular amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 ISO (PMID:3553851) RGD PMID:3553851 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
regulation of cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 ISO MGI:3608695 (MGI:3710059|PMID:17200146) RGD PMID:17200146 MGI:3710059 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:1926253 (MGI:3618656|PMID:11282258) RGD PMID:11282258 MGI:3618656 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Drd1 dopamine receptor D1 IEA
ISO
GO_REF:0000107
MGI:1857158 (MGI:2136539|PMID:11438590)
Ensembl
RGD
PMID:11438590 GO_REF:0000107, MGI:2136539 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd4 dopamine receptor D4 IEA
ISO
GO_REF:0000107
MGI:2178631 (MGI:1097029|PMID:9323127)
Ensembl
RGD
PMID:9323127 GO_REF:0000107, MGI:1097029 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISS
ISO
GO_REF:0000024
(MGI:1927024|PMID:11080193)
UniProt
RGD
PMID:11080193 GO_REF:0000024, MGI:1927024 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IEA
ISO
GO_REF:0000107
(MGI:2671567|PMID:12915123)
Ensembl
RGD
PMID:12915123 GO_REF:0000107, MGI:2671567 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Pde1b phosphodiesterase 1B ISO MGI:3604470 (MGI:3769297|PMID:17559891) RGD PMID:17559891 MGI:3769297 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing ISO MGI:5006973 (MGI:5466578|PMID:22214848) RGD PMID:22214848 MGI:5466578 NCBI chr 9:81,566,074...81,634,531
Ensembl chr 9:81,566,074...81,634,534
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:2386303 (MGI:2386819|PMID:9520487), (MGI:894559|PMID:9247269) RGD PMID:9247269, PMID:9520487 MGI:2386819, MGI:894559 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:8574643 RGD:2305963 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link
regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IDA RGD PMID:19858196 RGD:6484536 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Slc7a11 solute carrier family 7 member 11 ISO MGI:3608695 (MGI:4948153|PMID:21490221), (MGI:5562570|PMID:24548853), (MGI:5616960|PMID:25429150) RGD PMID:21490221, PMID:24548853, PMID:25429150 MGI:4948153, MGI:5562570, MGI:5616960 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
regulation of glutamine family amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 ISO (MGI:5490691|PMID:23562301) RGD PMID:23562301 MGI:5490691 NCBI chr12:46,862,358...46,876,593
Ensembl chr12:46,868,416...46,876,592
JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:23098818 RGD:11353778 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Tph1 tryptophan hydroxylase 1 TAS RGD PMID:12153488 RGD:625621 NCBI chr 1:102,669,868...102,699,442
Ensembl chr 1:102,669,868...102,699,442
JBrowse link
spermidine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA
ISO
IBA
(PMID:15283699)
PMID:21873635
RGD PMID:15283699, PMID:15541750, PMID:21873635 RGD:7244190, RGD:13792537 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT ISO
IBA
(PMID:12803540)
(PMID:15283699)
PMID:21873635
RGD PMID:12803540, PMID:15283699, PMID:21873635 RGD:13792537 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:160,306,754...160,321,951
Ensembl chr 5:160,306,727...160,321,066
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372, PMID:10430362, PMID:21873635, PMID:1415709, PMID:10712236 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G LOC100912604 spermidine synthase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,588,818...14,591,980
Ensembl chr 3:14,588,870...14,591,974
JBrowse link
G Srm spermidine synthase IDA
IBA
ISO
IMP
PMID:21873635
(PMID:17585781)
RGD PMID:17585781, PMID:12843627, PMID:21873635, PMID:8494549, PMID:16931179 RGD:1359042, RGD:13792537, RGD:7242928, RGD:7242920 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
spermidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase IDA RGD PMID:7721768 RGD:2316236 NCBI chr19:26,184,665...26,188,755
Ensembl chr19:26,184,545...26,188,832
JBrowse link
G Paox polyamine oxidase IDA
ISO
(PMID:16354669) RGD PMID:16354669, PMID:7560898, PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
spermidine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 ISS
ISO
GO_REF:0000024
(PMID:28516954)
UniProt
RGD
PMID:28516954 GO_REF:0000024 NCBI chr 7:130,102,335...130,109,036
Ensembl chr 7:130,102,347...130,107,437
JBrowse link
G Hdac6 histone deacetylase 6 NOT ISO (PMID:28516954) RGD PMID:28516954 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase ISO (PMID:23525104) RGD PMID:23525104 NCBI chr19:26,184,665...26,188,755
Ensembl chr19:26,184,545...26,188,832
JBrowse link
spermine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 IC RGD PMID:15541750 RGD:7244190 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372, PMID:10430362, PMID:21873635, PMID:1415709, PMID:10712236 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G Sms spermine synthase IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:8494549, PMID:21873635 RGD:7242928, RGD:13792537 NCBI chr  X:40,363,646...40,415,110
Ensembl chr  X:40,363,646...40,415,109
JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
(PMID:16354669) RGD PMID:16354669, PMID:7560898, PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Smox spermine oxidase IDA
ISO
(MGI:2429361|PMID:12141946)
(PMID:18422650)
RGD PMID:12141946, PMID:18422650, PMID:15541750 MGI:2429361, RGD:7244190 NCBI chr 3:124,068,796...124,103,726
Ensembl chr 3:124,068,865...124,102,240
JBrowse link
spermine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sms spermine synthase ISO MGI:2180359 (MGI:1197776|PMID:9467015) RGD PMID:9467015 MGI:1197776 NCBI chr  X:40,363,646...40,415,110
Ensembl chr  X:40,363,646...40,415,109
JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase IDA RGD PMID:11802786 RGD:70243 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase ISO (PMID:17334708) RGD PMID:17334708 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase IDA RGD PMID:7236232 RGD:2303721 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7236232, PMID:21873635 RGD:2303721, RGD:13792537 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IEA
ISO
IBA
GO_REF:0000041
(MGI:3587527|PMID:15866519)
PMID:21873635
UniProt
RGD
PMID:15866519, PMID:21873635 GO_REF:0000041, MGI:3587527, RGD:13792537 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IDA
ISO
IBA
IEA
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:2419335, PMID:11751753, PMID:10719243, PMID:21873635, PMID:11513477 GO_REF:0000107, MGI:2151782, MGI:2156954, RGD:2290190, RGD:13792537, RGD:2290543 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IEA
ISO
IBA
GO_REF:0000041
(MGI:3712725|PMID:17499941), (MGI:3719924|PMID:17671174)
PMID:21873635
(PMID:17671174)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17499941, PMID:17671174, PMID:21873635 GO_REF:0000041, GO_REF:0000107, MGI:3712725, MGI:3719924, RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kynu kynureninase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:27762317)
UniProt
RGD
PMID:27762317 GO_REF:0000024, GO_REF:0000041 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link
tryptophan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:1856102 (MGI:53851|PMID:4147174) RGD PMID:4147174 MGI:53851 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IDA RGD PMID:10719243, PMID:3899109, PMID:3400092 RGD:2290190, RGD:2291804, RGD:2290313 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        organonitrogen compound metabolic process 7134
          amine metabolic process 121
            2-aminobenzenesulfonate metabolic process + 0
            amine biosynthetic process + 41
            amine catabolic process + 23
            cellular amine metabolic process + 113
            cytokinin metabolic process + 0
            methane biosynthetic process from dimethylamine + 0
            methane biosynthetic process from trimethylamine + 0
            methylamine metabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.