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ONTOLOGY REPORT - ANNOTATIONS


Term:amine metabolic process
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Accession:GO:0009308 term browser browse the term
Definition:The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
Synonyms:exact_synonym: amine metabolism


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amine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aoc3 amine oxidase copper containing 3 ISO (PMID:9653080) UniProtKB PMID:9653080 NCBI chrNW_004936490:17,549,836...17,564,867 JBrowse link
G Inmt indolethylamine N-methyltransferase ISO (PMID:10552930) UniProtKB PMID:10552930 NCBI chrNW_004936478:6,997,605...7,002,649 JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO (MGI:3703667|PMID:17052995) MGI PMID:17052995 MGI:3703667 NCBI chrNW_004936471:33,682,730...33,688,332 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO (PMID:23474851) UniProtKB PMID:23474851 NCBI chrNW_004936748:785,491...802,791 JBrowse link
benzylpenicillin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 ISO RGD PMID:19255943 RGD:11081014 NCBI chrNW_004936636:292,631...341,999 JBrowse link
catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 ISO RGD PMID:17194738 RGD:5131263 NCBI chrNW_004936478:6,901,098...6,947,719 JBrowse link
G Th tyrosine hydroxylase ISO RGD PMID:20025246 RGD:4139888 NCBI chrNW_004936794:478,651...486,887 JBrowse link
catecholamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO (PMID:11559542), (PMID:15645182), (PMID:21846718) UniProt PMID:11559542, PMID:15645182, PMID:21846718 NCBI chrNW_004936619:3,847,059...3,883,866 JBrowse link
catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO (MGI:54307|PMID:17511) MGI PMID:17511 MGI:54307 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
G Mtpn myotrophin ISO RGD PMID:12051753 RGD:625450 NCBI chrNW_004936592:644,618...679,615 JBrowse link
cellular biogenic amine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mecp2 methyl-CpG binding protein 2 ISO (MGI:3607765|PMID:15975715) MGI PMID:15975715 MGI:3607765 NCBI chrNW_004936809:902,938...967,771 JBrowse link
choline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase ISO (PMID:10102904) UniProtKB PMID:10102904 NCBI chrNW_004936549:6,838,773...6,899,961 JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:20097214 RGD:6903884 NCBI chrNW_004936519:6,831,096...6,873,977 JBrowse link
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:20097214 RGD:6903884 NCBI chrNW_004936479:13,252,678...13,255,570 JBrowse link
G Dao D-amino acid oxidase ISO (PMID:17303072) UniProtKB PMID:17303072 NCBI chrNW_004936769:744,862...758,086 JBrowse link
G Ddc dopa decarboxylase ISO RGD PMID:12703659 RGD:4139893 NCBI chrNW_004936686:1,322,153...1,405,434 JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO (PMID:16338639) UniProtKB PMID:16338639 NCBI chrNW_004936697:232,048...275,420 JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO (MGI:3046856|PMID:15218106) MGI PMID:15218106 MGI:3046856 NCBI chrNW_004936605:978,174...997,093 JBrowse link
G Nr4a2 nuclear receptor subfamily 4 group A member 2 ISO (MGI:1203924|PMID:9608532), (MGI:3767764|PMID:16782508) MGI PMID:9608532, PMID:16782508 MGI:1203924, MGI:3767764 NCBI chrNW_004936469:21,912,118...21,920,486 JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO (MGI:2386819|PMID:9520487) MGI PMID:9520487 MGI:2386819 NCBI chrNW_004936815:359,775...400,690 JBrowse link
G Snca synuclein alpha ISO (MGI:1352916|PMID:10707987) MGI PMID:10707987 MGI:1352916 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO (MGI:3622848|PMID:16257223) UniProt PMID:16257223 MGI:3622848 NCBI chrNW_004936628:310,720...394,002 JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) BHF-UCL PMID:12457228 NCBI chrNW_004936794:478,651...486,887 JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase ISO PMID:11943812
(MGI:2386819|PMID:9520487)
(MGI:72094|PMID:7715703), (MGI:77787|PMID:7592982)
BHF-UCL
MGI
RGD
PMID:2427363, PMID:7592982, PMID:7715703, PMID:9520487, PMID:11943812, PMID:19584816 MGI:2386819, MGI:72094, MGI:77787, RGD:1580046, RGD:5129111, RGD:5130972 NCBI chrNW_004936794:478,651...486,887 JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO (MGI:2386819|PMID:9520487) MGI PMID:9520487 MGI:2386819 NCBI chrNW_004936619:3,847,059...3,883,866 JBrowse link
G Dbh dopamine beta-hydroxylase ISO (PMID:3443096), (PMID:7961964)
(MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
(MGI:1332340|PMID:10051631)
UniProtKB
UniProt
MGI
PMID:3443096, PMID:7715704, PMID:7961964, PMID:10051631, PMID:27148966 MGI:1332340, MGI:5787847, MGI:72180 NCBI chrNW_004936669:3,302,014...3,326,233 JBrowse link
G Maoa monoamine oxidase A ISO (MGI:2386819|PMID:9520487) MGI PMID:9520487 MGI:2386819 NCBI chrNW_004936502:9,816,443...9,888,002 JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO (MGI:2386819|PMID:9520487) MGI PMID:9520487 MGI:2386819 NCBI chrNW_004936815:359,775...400,690 JBrowse link
dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO (MGI:50550|PMID:1752214), (MGI:65000|PMID:8174230) MGI PMID:1752214, PMID:8174230 MGI:50550, MGI:65000, MGI:71923 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
G Comt catechol-O-methyltransferase ISO (MGI:5510279|PMID:23863468)
(MGI:4830461|PMID:19930170)
MGI PMID:19930170, PMID:23863468 MGI:4830461, MGI:5510279 NCBI chrNW_004936619:3,847,059...3,883,866 JBrowse link
G Drd2 dopamine receptor D2 ISO (MGI:68905|PMID:7925842) MGI PMID:7925842 MGI:68905 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO (MGI:2384280|PMID:11160454) MGI PMID:11160454 MGI:2384280 NCBI chrNW_004936530:8,286,101...8,612,183 JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO (MGI:1321418|PMID:9886073), (MGI:65825|PMID:7509865), (MGI:65928|PMID:1432691) MGI PMID:1432691, PMID:7509865, PMID:9886073 MGI:1321418, MGI:65825, MGI:65928 NCBI chrNW_004936691:650,753...694,362 JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 ISO (MGI:6150107|PMID:28327638) MGI PMID:28327638 MGI:6150107 NCBI chrNW_004936480:13,829,093...13,932,202 JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO RGD PMID:15544851 RGD:1580153 NCBI chrNW_004936580:3,479,858...3,496,896 JBrowse link
G Nr4a2 nuclear receptor subfamily 4 group A member 2 ISO (MGI:3529728|PMID:12385813) MGI PMID:12385813 MGI:3529728 NCBI chrNW_004936469:21,912,118...21,920,486 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase NOT ISO (MGI:2675710|PMID:12915482)
(MGI:3525458|PMID:15684050)
MGI PMID:12915482, PMID:15684050 MGI:2675710, MGI:3525458 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Snca synuclein alpha ISO (MGI:3057254|PMID:15465911) MGI PMID:15465911 MGI:3057254 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
G Sncaip synuclein alpha interacting protein ISO (PMID:14506261) MGI PMID:14506261 NCBI chrNW_004936575:2,727,253...2,873,428 JBrowse link
G Sncb synuclein beta ISO (MGI:3057254|PMID:15465911) MGI PMID:15465911 MGI:3057254 NCBI chrNW_004936597:878,270...888,346 JBrowse link
G Spr sepiapterin reductase ISO (MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:3722569 NCBI chrNW_004936491:16,693,940...16,699,040 JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnmt phenylethanolamine N-methyltransferase ISO RGD PMID:7914070 RGD:4139902 NCBI chrNW_004936490:14,858,682...14,861,614 JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) BHF-UCL PMID:12457228 NCBI chrNW_004936794:478,651...486,887 JBrowse link
epinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO (MGI:50550|PMID:1752214) MGI PMID:1752214 MGI:50550, MGI:71923 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
ethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chka choline kinase alpha ISO RGD PMID:1577786 RGD:61551 NCBI chrNW_004936599:2,031,953...2,068,423 JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 ISO (MGI:3793397|PMID:18227059) UniProt PMID:18227059 MGI:3793397 NCBI chrNW_004936501:5,177,511...5,193,484 JBrowse link
histamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase ISO (PMID:22767596)
(MGI:2138019|PMID:11478947)
UniProtKB
MGI
PMID:11478947, PMID:22767596 MGI:2138019 NCBI chrNW_004936471:12,303,802...12,324,613 JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 ISO (PMID:10318872) UniProtKB PMID:10318872 NCBI chrNW_004936581:5,109,165...5,113,617 JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase ISO (PMID:26206890) UniProtKB PMID:26206890 NCBI chrNW_004936469:38,125,877...38,166,429 JBrowse link
histamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdc histidine decarboxylase ISO RGD PMID:5898, PMID:4449071, PMID:7075603, PMID:9525922 RGD:2303726, RGD:2303727, RGD:2303728, RGD:2303735 NCBI chrNW_004936471:12,303,802...12,324,613 JBrowse link
G Hnmt histamine N-methyltransferase ISO (PMID:23505051) ARUK-UCL PMID:23505051 NCBI chrNW_004936469:38,125,877...38,166,429 JBrowse link
G Trh thyrotropin releasing hormone ISO RGD PMID:17760865 RGD:7241067 NCBI chrNW_004936602:623,542...626,337 JBrowse link
N-acylethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B ISO (MGI:3695251|PMID:16818490) MGI PMID:16818490 MGI:3695251 NCBI chrNW_004936722:1,658,287...1,671,848 JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 ISO (MGI:5295534|PMID:21801852)
(MGI:5790171|PMID:25596343)
UniProt
MGI
PMID:21801852, PMID:25596343 MGI:5295534, MGI:5790171 NCBI chrNW_004936501:5,177,511...5,193,484 JBrowse link
G Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 ISO (PMID:25596343), (PMID:27637550)
(MGI:5790171|PMID:25596343)
(MGI:6104349|PMID:27637550)
MGI
UniProt
PMID:25596343, PMID:27637550 MGI:5790171, MGI:6104349 NCBI chrNW_004936490:4,032,412...4,079,243 JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 ISO (PMID:27637550)
(MGI:6104349|PMID:27637550)
UniProt PMID:27637550 MGI:6104349 NCBI chrNW_004936501:12,391,204...12,397,877 JBrowse link
G Naaa N-acylethanolamine acid amidase ISO (PMID:15655246), (PMID:30301806)
PMID:22860206
UniProt PMID:15655246, PMID:22860206, PMID:30301806 RGD:39458030 NCBI chrNW_004936598:42,751...56,261 JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D ISO (MGI:3695251|PMID:16818490)
(MGI:3044670|PMID:14634025)
MGI PMID:14634025, PMID:16818490 MGI:3044670, MGI:3695251 NCBI chrNW_004936479:20,259,260...20,293,116 JBrowse link
negative regulation of arginine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO (PMID:19278978) BHF-UCL PMID:19278978 NCBI chrNW_004936567:944,825...1,039,920 JBrowse link
negative regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO (MGI:54307|PMID:17511) MGI PMID:17511 MGI:54307 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO (PMID:19278978) BHF-UCL PMID:19278978 NCBI chrNW_004936567:944,825...1,039,920 JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO RGD PMID:15190105 RGD:2289786 NCBI chrNW_004936619:3,847,059...3,883,866 JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO RGD PMID:17018023 RGD:1625003 NCBI chrNW_004936499:1,002,083...1,109,446 JBrowse link
G Itgam integrin subunit alpha M ISO (MGI:3814938|PMID:18981141) ARUK-UCL PMID:18981141 MGI:3814938 NCBI chrNW_004936543:8,460,526...8,508,524 JBrowse link
G Snca synuclein alpha ISO PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atcay ATCAY kinesin light chain interacting caytaxin ISO (PMID:16899818) UniProtKB PMID:16899818 NCBI chrNW_004936588:2,196,556...2,226,489 JBrowse link
nor-spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) UniProtKB PMID:12803540 NCBI chrNW_004936595:891,380...892,937 JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO (MGI:53940|PMID:4858102)
(MGI:53801|PMID:4405722)
MGI PMID:4405722, PMID:4858102 MGI:53801, MGI:53940 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
G Dbh dopamine beta-hydroxylase ISO (MGI:1203930|PMID:9603211), (MGI:1332340|PMID:10051631)
(MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
(PMID:27148966)
RGD
MGI
UniProt
UniProtKB
PMID:7715704, PMID:9603211, PMID:10051631, PMID:10573542, PMID:27148966 MGI:1203930, MGI:1332340, MGI:5787847, MGI:72180, RGD:1625403 NCBI chrNW_004936669:3,302,014...3,326,233 JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chrNW_004936508:5,855,748...5,938,879 JBrowse link
G Gata3 GATA binding protein 3 ISO (MGI:1859081|PMID:10835639) MGI PMID:10835639 MGI:1859081 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G Insm1 INSM transcriptional repressor 1 ISO (MGI:3772428|PMID:18094025) UniProt PMID:18094025 MGI:3772428 NCBI chrNW_004936485:66,889...69,792 JBrowse link
G Kl klotho ISO RGD PMID:20086041 RGD:10403068 NCBI chrNW_004936472:27,604,681...27,649,613 JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) BHF-UCL PMID:12457228 NCBI chrNW_004936794:478,651...486,887 JBrowse link
norepinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B ISO RGD PMID:10424772 RGD:8548769 NCBI chrNW_004936579:1,312,175...1,328,397 JBrowse link
G Atp7a ATPase copper transporting alpha ISO (MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:53851, MGI:71923 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO (MGI:1313089|PMID:9808618) MGI PMID:9808618 MGI:1313089 NCBI chrNW_004936508:5,855,748...5,938,879 JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO (MGI:2157257|PMID:11784869) MGI PMID:11784869 MGI:2157257 NCBI chrNW_004936470:8,879,217...8,880,777 JBrowse link
G Pnmt phenylethanolamine N-methyltransferase ISO RGD PMID:3945626 RGD:5130757 NCBI chrNW_004936490:14,858,682...14,861,614 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (MGI:3047192|PMID:15249681) MGI PMID:15249681 MGI:3047192 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Rnf180 ring finger protein 180 ISO (MGI:5505713|PMID:23926250) MGI PMID:23926250 MGI:5505713 NCBI chrNW_004936480:4,809,103...4,834,977 JBrowse link
G Rtl4 retrotransposon Gag like 4 ISO (MGI:5749620|PMID:26402067) MGI PMID:26402067 MGI:5749620 NCBI chrNW_004936499:2,901,534...2,904,565 JBrowse link
G Spr sepiapterin reductase ISO (MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:3722569 NCBI chrNW_004936491:16,693,940...16,699,040 JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase ISO RGD PMID:11521740 RGD:1625401 NCBI chrNW_004936669:3,302,014...3,326,233 JBrowse link
phenylethylamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Maoa monoamine oxidase A ISO Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741 RGD:1600709 NCBI chrNW_004936502:9,816,443...9,888,002 JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyltransferase 1 ISO (PMID:15283699) UniProt PMID:15283699 NCBI chrNW_004936624:756,761...759,979 JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT ISO (PMID:15283699) UniProt PMID:15283699 NCBI chrNW_004936595:891,380...892,937 JBrowse link
polyamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase ISO (PMID:12477380)
(MGI:2663545|PMID:12660232)
UniProtKB
MGI
RGD
PMID:12477380, PMID:12660232, PMID:15541750 MGI:2663545, RGD:7244190 NCBI chrNW_004936486:19,503,631...19,511,918 JBrowse link
G Sat1 spermidine/spermine N1-acetyltransferase 1 ISO RGD PMID:15541750 RGD:7244190 NCBI chrNW_004936624:756,761...759,979 JBrowse link
G Smox spermine oxidase ISO (PMID:12477380) UniProtKB PMID:12477380 NCBI chrNW_004936485:14,566,570...14,603,323 JBrowse link
polyamine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 ISO (PMID:28516954) UniProt PMID:28516954 NCBI chrNW_004936629:562,038...567,709 JBrowse link
G Hdac6 histone deacetylase 6 NOT ISO (PMID:28516954) UniProt PMID:28516954 NCBI chrNW_004936721:757,500...778,416 JBrowse link
polyamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 ISO RGD PMID:10430362 RGD:1578320 NCBI chrNW_004936564:6,656,789...6,675,564 JBrowse link
G Odc1 ornithine decarboxylase 1 ISO RGD PMID:10430362 RGD:1578320 NCBI chrNW_004936532:6,581,717...6,587,116 JBrowse link
G Sat1 spermidine/spermine N1-acetyltransferase 1 ISO RGD PMID:11172929 RGD:1599544 NCBI chrNW_004936624:756,761...759,979 JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:8888012 RGD:2302806 NCBI chrNW_004936668:2,316,661...2,323,015 JBrowse link
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO (MGI:5306122|PMID:21757002) BHF-UCL PMID:21757002 MGI:5306122 NCBI chrNW_004936492:13,315,265...13,365,186 JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chrNW_004936508:5,855,748...5,938,879 JBrowse link
G Park7 Parkinsonism associated deglycase ISO (PMID:19703902) ParkinsonsUK-UCL PMID:19703902 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Vps35 VPS35 retromer complex component ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chrNW_004936475:50,476...77,797 JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:11239920 RGD:10047061 NCBI chrNW_004936530:7,543,743...7,621,392 JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO (MGI:3046856|PMID:15218106) MGI PMID:15218106 MGI:3046856 NCBI chrNW_004936605:978,174...997,093 JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO (PMID:8643611) UniProtKB PMID:8643611 NCBI chrNW_004936691:650,753...694,362 JBrowse link
G Maob monoamine oxidase B ISO RGD PMID:12175458 RGD:2316765 NCBI chrNW_004936502:9,907,181...10,014,756 JBrowse link
G Npy neuropeptide Y ISO RGD PMID:19579268 RGD:10448966 NCBI chrNW_004936478:1,289,437...1,296,819 JBrowse link
positive regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO (MGI:5306122|PMID:21757002) BHF-UCL PMID:21757002 MGI:5306122 NCBI chrNW_004936492:13,315,265...13,365,186 JBrowse link
positive regulation of homocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO RGD PMID:15779086 RGD:2289784 NCBI chrNW_004936619:3,847,059...3,883,866 JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO (PMID:16731528) ParkinsonsUK-UCL PMID:16731528 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase ISO (PMID:16354669) UniProtKB PMID:16354669 NCBI chrNW_004936486:19,503,631...19,511,918 JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 ISO (MGI:4413411|PMID:19008477) BHF-UCL PMID:19008477 MGI:4413411 NCBI chrNW_004936516:4,692,926...4,695,625 JBrowse link
putrescine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) UniProtKB PMID:12803540 NCBI chrNW_004936595:891,380...892,937 JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 ISO RGD PMID:1415709, PMID:10430362 RGD:1578320, RGD:7242912 NCBI chrNW_004936532:6,581,717...6,587,116 JBrowse link
G Paox polyamine oxidase ISO (PMID:16354669) UniProtKB PMID:16354669 NCBI chrNW_004936486:19,503,631...19,511,918 JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 ISO (MGI:5574513|PMID:24967154) UniProt PMID:24967154 MGI:5574513 NCBI chrNW_004936532:6,581,717...6,587,116 JBrowse link
putrescine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase ISO (PMID:16354669) UniProtKB
UniProt
PMID:16354669 RGD:12790650 NCBI chrNW_004936486:19,503,631...19,511,918 JBrowse link
putrescine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aoc1 amine oxidase copper containing 1 ISO (PMID:8144586) UniProt PMID:8144586 NCBI chrNW_004936527:6,309,210...6,312,869 JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor ISO (MGI:3628883|PMID:12204217) MGI PMID:12204217 MGI:3628883 NCBI chrNW_004936508:3,601,205...3,754,234 JBrowse link
regulation of arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:4830440|PMID:19284480) UniProt PMID:19284480 MGI:4830440 NCBI chrNW_004936501:11,955,334...11,967,338 JBrowse link
regulation of arginine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fh fumarate hydratase ISO (MGI:5496931|PMID:23643539) UniProt PMID:23643539 MGI:5496931 NCBI chrNW_004936526:8,936,096...8,965,155 JBrowse link
G Slc7a7 solute carrier family 7 member 7 ISO (MGI:3760035|PMID:17376816) MGI PMID:17376816 MGI:3760035 NCBI chrNW_004936722:1,464,252...1,523,786 JBrowse link
regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vhl von Hippel-Lindau tumor suppressor ISO RGD PMID:11912140 RGD:619592 NCBI chrNW_004936602:3,135,790...3,140,622 JBrowse link
regulation of cellular amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins insulin ISO (PMID:3553851) BHF-UCL PMID:3553851 NCBI chrNW_004936816:1,002,137...1,003,357 JBrowse link
regulation of cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 ISO (MGI:3710059|PMID:17200146) MGI PMID:17200146 MGI:3710059 NCBI chrNW_004936535:9,177,305...9,242,743 JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:3618656|PMID:11282258) MGI PMID:11282258 MGI:3618656 NCBI chrNW_004936580:4,165,255...4,179,285 JBrowse link
G Drd1 dopamine receptor D1 ISO (MGI:2136539|PMID:11438590) MGI PMID:11438590 MGI:2136539 NCBI chrNW_004936609:790,647...795,187 JBrowse link
G Drd4 dopamine receptor D4 ISO (MGI:1097029|PMID:9323127) MGI PMID:9323127 MGI:1097029 NCBI chrNW_004936888:468,334...471,254 JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO (MGI:1927024|PMID:11080193) UniProt PMID:11080193 MGI:1927024 NCBI chrNW_004936480:5,042,531...5,047,157 JBrowse link
G Nr4a2 nuclear receptor subfamily 4 group A member 2 ISO (MGI:2671567|PMID:12915123) MGI PMID:12915123 MGI:2671567 NCBI chrNW_004936469:21,912,118...21,920,486 JBrowse link
G Pde1b phosphodiesterase 1B ISO (MGI:3769297|PMID:17559891) MGI PMID:17559891 MGI:3769297 NCBI chrNW_004936512:11,739,219...11,766,264 JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing ISO (MGI:5466578|PMID:22214848) MGI PMID:22214848 MGI:5466578 NCBI chrNW_004936569:799,963...865,462 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:22314364) ParkinsonsUK-UCL PMID:22314364 NCBI chrNW_004936489:12,118,538...12,913,664 JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO (MGI:2386819|PMID:9520487), (MGI:894559|PMID:9247269) MGI PMID:9247269, PMID:9520487 MGI:2386819, MGI:894559 NCBI chrNW_004936815:359,775...400,690 JBrowse link
regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO RGD PMID:19858196 RGD:6484536 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Slc7a11 solute carrier family 7 member 11 ISO (MGI:5562570|PMID:24548853)
(MGI:4948153|PMID:21490221), (MGI:5616960|PMID:25429150)
MGI PMID:21490221, PMID:24548853, PMID:25429150 MGI:4948153, MGI:5562570, MGI:5616960 NCBI chrNW_004936535:9,177,305...9,242,743 JBrowse link
regulation of glutamine family amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 ISO (MGI:5490691|PMID:23562301) CACAO PMID:23562301 MGI:5490691 NCBI chrNW_004936668:628,875...633,425 JBrowse link
spermidine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyltransferase 1 ISO (PMID:15283699) RGD
UniProt
PMID:15283699, PMID:15541750 RGD:7244190 NCBI chrNW_004936624:756,761...759,979 JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT ISO (PMID:12803540)
(PMID:15283699)
UniProtKB
UniProt
PMID:12803540, PMID:15283699 NCBI chrNW_004936595:891,380...892,937 JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 ISO (MGI:3584197|PMID:11856372) RGD
MGI
PMID:1415709, PMID:10430362, PMID:10712236, PMID:11856372 MGI:3584197, RGD:1578320, RGD:7242911, RGD:7242912 NCBI chrNW_004936564:6,656,789...6,675,564 JBrowse link
G Srm spermidine synthase ISO (PMID:17585781) RGD
UniProtKB
PMID:8494549, PMID:12843627, PMID:16931179, PMID:17585781 RGD:1359042, RGD:7242920, RGD:7242928 NCBI chrNW_004936474:121,135...124,894 JBrowse link
spermidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase ISO RGD PMID:7721768 RGD:2316236 NCBI chrNW_004936659:1,803,581...1,810,121 JBrowse link
G Paox polyamine oxidase ISO (PMID:16354669) UniProtKB
RGD
UniProt
PMID:7560898, PMID:16354669 RGD:12790650, RGD:7244191 NCBI chrNW_004936486:19,503,631...19,511,918 JBrowse link
spermidine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 ISO (PMID:28516954) UniProt PMID:28516954 NCBI chrNW_004936629:562,038...567,709 JBrowse link
G Hdac6 histone deacetylase 6 NOT ISO (PMID:28516954) UniProt PMID:28516954 NCBI chrNW_004936721:757,500...778,416 JBrowse link
spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase ISO (PMID:23525104) UniProtKB PMID:23525104 NCBI chrNW_004936659:1,803,581...1,810,121 JBrowse link
spermine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) UniProtKB PMID:12803540 NCBI chrNW_004936595:891,380...892,937 JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 ISO (MGI:3584197|PMID:11856372) RGD
MGI
PMID:1415709, PMID:10430362, PMID:10712236, PMID:11856372 MGI:3584197, RGD:1578320, RGD:7242911, RGD:7242912 NCBI chrNW_004936564:6,656,789...6,675,564 JBrowse link
G Sms spermine synthase ISO RGD PMID:8494549 RGD:7242928 NCBI chrNW_004936624:2,345,573...2,402,157 JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase ISO PMID:16354669
(PMID:16354669)
UniProt
RGD
UniProtKB
PMID:7560898, PMID:16354669 RGD:12790650, RGD:7244191 NCBI chrNW_004936486:19,503,631...19,511,918 JBrowse link
G Smox spermine oxidase ISO (PMID:18422650)
(MGI:2429361|PMID:12141946)
UniProtKB
MGI
RGD
PMID:12141946, PMID:15541750, PMID:18422650 MGI:2429361, RGD:7244190 NCBI chrNW_004936485:14,566,570...14,603,323 JBrowse link
spermine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sms spermine synthase ISO (MGI:1197776|PMID:9467015) MGI PMID:9467015 MGI:1197776 NCBI chrNW_004936624:2,345,573...2,402,157 JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase ISO RGD PMID:11802786 RGD:70243 NCBI chrNW_004936469:40,858,338...40,904,807 JBrowse link
G Kynu kynureninase ISO (PMID:17334708) UniProtKB PMID:17334708 NCBI chrNW_004936469:33,632,885...33,805,158 JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase ISO RGD PMID:7236232 RGD:2303721 NCBI chrNW_004936469:33,632,885...33,805,158 JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO RGD PMID:7236232 RGD:2303721 NCBI chrNW_004936576:2,537,702...2,555,790 JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase ISO (MGI:3587527|PMID:15866519) MGI PMID:15866519 MGI:3587527 NCBI chrNW_004936594:2,794,927...2,805,689 JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 ISO (MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753) RGD
MGI
PMID:2419335, PMID:10719243, PMID:11513477, PMID:11751753 MGI:2151782, MGI:2156954, RGD:2290190, RGD:2290543 NCBI chrNW_004936843:658,058...672,662 JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 ISO (PMID:17671174)
(MGI:3719924|PMID:17671174)
(MGI:3712725|PMID:17499941)
UniProtKB
MGI
PMID:17499941, PMID:17671174 MGI:3712725, MGI:3719924 NCBI chrNW_004936843:595,237...649,390 JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO (PMID:27762317) UniProtKB PMID:27762317 NCBI chrNW_004936576:2,537,702...2,555,790 JBrowse link
tryptophan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO (MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:53851 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO RGD PMID:3400092, PMID:3899109, PMID:10719243 RGD:2290190, RGD:2290313, RGD:2291804 NCBI chrNW_004936576:2,537,702...2,555,790 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12003
    metabolic process 7586
      organic substance metabolic process 7279
        organonitrogen compound metabolic process 4330
          amine metabolic process 98
            2-aminobenzenesulfonate metabolic process + 0
            amine biosynthetic process + 31
            amine catabolic process + 17
            cellular amine metabolic process + 94
            cytokinin metabolic process + 0
            methane biosynthetic process from dimethylamine + 0
            methane biosynthetic process from trimethylamine + 0
            methylamine metabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.