ONTOLOGY REPORT - ANNOTATIONS


Term:response to heat
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Accession:GO:0009408 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
Synonyms:narrow_synonym: response to heat shock
 alt_id: GO:0006951
 xref: MIPS_funcat:32.01.05


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response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:1598611
G Aldoa aldolase, fructose-bisphosphate A JBrowse link 1 198,228,387 198,233,988 RGD:1599061
G Asic3 acid sensing ion channel subunit 3 JBrowse link 4 7,287,868 7,293,295 RGD:1624291
RGD:1600115
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1599475
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1624291
RGD:1600115
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:2301325
G Casq1 calsequestrin 1 JBrowse link 13 90,592,676 90,602,365 RGD:1624291
RGD:1600115
G Cckar cholecystokinin A receptor JBrowse link 14 59,610,939 59,619,786 RGD:2313358
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:2307043
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:2313390
G Ckm creatine kinase, M-type JBrowse link 1 80,321,507 80,331,841 RGD:1600115
G Cpb2 carboxypeptidase B2 JBrowse link 15 57,290,849 57,339,762 RGD:2313648
G Crnn cornulin JBrowse link 2 193,427,097 193,432,070 RGD:1624291
RGD:1600115
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:2314489
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:2306574
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:2314489
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 5 57,028,467 57,039,378 RGD:1600115
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 JBrowse link 19 22,569,999 22,588,143 RGD:1600115
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1600115
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 JBrowse link 8 59,278,262 59,294,003 RGD:1600115
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:9588227
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha JBrowse link 12 37,444,136 37,452,391 RGD:8554311
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta JBrowse link 6 109,044,830 109,051,254 RGD:8554311
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma JBrowse link 5 135,882,946 135,949,276 RGD:8554311
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta JBrowse link 6 26,546,917 26,552,474 RGD:8554311
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link 11 84,080,273 84,090,259 RGD:8554311
RGD:1600115
RGD:1624291
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:1624291
RGD:1600115
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:5684987
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:1626383
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:1624291
RGD:10402365
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:2316945
RGD:1600115
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Hspa2 heat shock protein family A (Hsp70) member 2 JBrowse link 6 99,433,575 99,436,288 RGD:1600115
G Hspa4 heat shock protein family A (Hsp70) member 4 JBrowse link 10 38,601,624 38,642,397 RGD:633150
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:10059374
G Hspb2 heat shock protein family B (small) member 2 JBrowse link 8 55,176,648 55,178,227 RGD:70771
G Hspb7 heat shock protein family B (small) member 7 JBrowse link 5 159,968,077 159,971,563 RGD:61631
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624223
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
G Igfbp7 insulin-like growth factor binding protein 7 JBrowse link 14 33,010,300 33,070,193 RGD:1626551
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:4142847
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1626650
RGD:12902613
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2306933
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:5128783
G Kat5 lysine acetyltransferase 5 JBrowse link 1 220,967,795 220,974,596 RGD:9588482
G LOC103692716 heat shock protein HSP 90-alpha JBrowse link 6 135,044,833 135,050,417 RGD:1600115
G Lrp11 LDL receptor related protein 11 JBrowse link 1 1,702,696 1,731,210 RGD:1624291
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:1600115
RGD:1624291
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:1582333
G Micb MHC class I polypeptide-related sequence B JBrowse link 1 79,754,587 79,772,092 RGD:1624291
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1642001
G Mill1 MHC I like leukocyte 1 JBrowse link 1 79,631,266 79,657,943 RGD:1624291
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1642051
G Mstn myostatin JBrowse link 9 53,310,977 53,315,804 RGD:2303598
G Mt-cyb mitochondrially encoded cytochrome b JBrowse link MT 14,136 15,278 RGD:2298970
G Myh6 myosin heavy chain 6 JBrowse link 15 33,605,653 33,629,730 RGD:7247703
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1642129
RGD:1600115
RGD:1624291
G Osm oncostatin M JBrowse link 14 84,457,487 84,469,426 RGD:1624291
G P2rx3 purinergic receptor P2X 3 JBrowse link 3 72,403,992 72,447,801 RGD:1624291
RGD:1600115
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:13782127
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:2302801
G Pirt phosphoinositide-interacting regulator of transient receptor potential channels JBrowse link 10 53,466,870 53,485,096 RGD:1624291
RGD:1600115
G Pklr pyruvate kinase L/R JBrowse link 2 188,449,158 188,458,034 RGD:1625591
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1642444
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1642547
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1625613
G Psip1 PC4 and SFRS1 interacting protein 1 JBrowse link 5 101,555,691 101,588,659 RGD:1600115
RGD:1624291
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:1643025
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:730264
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
RGD:1600115
G Sst somatostatin JBrowse link 11 80,358,172 80,359,449 RGD:2303176
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:2304333
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 JBrowse link 1 199,664,039 199,670,970 RGD:634226
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 JBrowse link 5 24,402,895 24,419,651 RGD:1624291
RGD:1600115
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:1624291
RGD:1600115
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:70055
RGD:1624291
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 JBrowse link 10 48,903,540 48,925,036 RGD:70055
RGD:1600115
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 JBrowse link 10 59,829,755 59,863,780 RGD:7175559
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:13210576
cellular heat acclimation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsbp1 heat shock factor binding protein 1 JBrowse link 19 51,985,196 51,989,528 RGD:13792537
G Hsbp1l1 heat shock factor binding protein 1-like 1 JBrowse link 18 76,748,067 76,754,642 RGD:13792537
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Rbbp7 RB binding protein 7, chromatin remodeling factor JBrowse link X 33,648,682 33,665,821 RGD:1624291
RGD:1600115
cellular response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ano1 anoctamin 1 JBrowse link 1 217,754,349 217,902,540 RGD:1624291
RGD:1600115
G Arpp21 cAMP regulated phosphoprotein 21 JBrowse link 8 120,323,895 120,492,790 RGD:1624291
RGD:1600115
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:10047286
G Atxn3 ataxin 3 JBrowse link 6 125,817,420 125,853,461 RGD:1624291
RGD:1600115
G Bag3 Bcl2-associated athanogene 3 JBrowse link 1 199,941,258 199,965,191 RGD:1624291
RGD:1600115
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8547793
G Cetn1 centrin 1 JBrowse link 18 785,972 786,674 RGD:1624291
RGD:1600115
G Cftr cystic fibrosis transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11567213
G Clpb ClpB homolog, mitochondrial AAA ATPase chaperonin JBrowse link 1 166,739,372 166,866,095 RGD:1600115
RGD:1624291
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:2311382
G Daxx death-domain associated protein JBrowse link 20 5,480,103 5,485,962 RGD:1624291
RGD:1600115
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link 6 102,048,372 102,073,041 RGD:10395354
RGD:10395357
G Fgf1 fibroblast growth factor 1 JBrowse link 18 32,273,830 32,359,831 RGD:1624291
RGD:1600115
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:2306446
G Hikeshi heat shock protein nuclear import factor JBrowse link 1 154,147,098 154,170,429 RGD:1600115
RGD:1624291
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1624291
RGD:1600115
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:10402942
RGD:13792537
RGD:1624291
G Hsf2 heat shock transcription factor 2 JBrowse link 20 38,935,820 38,963,444 RGD:13792537
G Hsf4 heat shock transcription factor 4 JBrowse link 19 37,225,800 37,232,048 RGD:13792537
G Hsfy2 heat shock transcription factor, Y linked 2 JBrowse link 9 63,289,937 63,291,350 RGD:13792537
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:13792537
G Hspa13 heat shock protein family A (Hsp70) member 13 JBrowse link 11 14,146,515 14,160,697 RGD:13792537
G Hspa14 heat shock protein family A (Hsp70) member 14 JBrowse link 17 78,735,630 78,756,412 RGD:13792537
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
RGD:13792537
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
RGD:13792537
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:13792537
G Hspa2 heat shock protein family A (Hsp70) member 2 JBrowse link 6 99,433,575 99,436,288 RGD:13792537
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:13792537
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:10059375
RGD:13792537
G Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link 18 27,731,072 27,749,235 RGD:13792537
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:12910540
G Htra2 HtrA serine peptidase 2 JBrowse link 4 113,883,671 113,886,833 RGD:1624291
RGD:1600115
G Ier5 immediate early response 5 JBrowse link 13 72,742,210 72,744,302 RGD:1624291
RGD:1600115
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:1600115
RGD:1624291
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:7495799
G LOC103692716 heat shock protein HSP 90-alpha JBrowse link 6 135,044,833 135,050,417 RGD:13792537
G LOC108348108 heat shock 70 kDa protein 1A JBrowse link 20 2,699,707 2,701,856 RGD:13792537
G LOC680121 similar to heat shock protein 8 JBrowse link 11 13,499,168 13,501,271 RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:2303719
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:2317714
G Myof myoferlin JBrowse link 1 256,585,410 256,734,727 RGD:1624291
RGD:1600115
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:5132625
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1624291
RGD:1600115
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:1624291
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1624291
RGD:1600115
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11567213
G Rasa3 RAS p21 protein activator 3 JBrowse link 16 81,320,090 81,434,239 RGD:10047323
G Scara5 scavenger receptor class A, member 5 JBrowse link 15 49,069,142 49,177,159 RGD:1624291
RGD:1600115
G Slc52a3 solute carrier family 52 member 3 JBrowse link 3 147,503,266 147,517,935 RGD:1624291
RGD:1600115
G Slu7 SLU7 homolog, splicing factor JBrowse link 10 29,029,556 29,044,919 RGD:1624291
RGD:1600115
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 JBrowse link 4 177,065,266 177,195,942 RGD:1624291
RGD:1600115
G Stac SH3 and cysteine rich domain JBrowse link 8 119,820,664 119,941,867 RGD:1624291
RGD:1600115
G Stub1 STIP1 homology and U-box containing protein 1 JBrowse link 10 15,197,754 15,200,035 RGD:13507303
G Sumo1 small ubiquitin-like modifier 1 JBrowse link 9 66,453,428 66,483,614 RGD:1624291
RGD:1600115
G Tcim transcriptional and immune response regulator JBrowse link 16 72,401,526 72,403,180 RGD:1624291
G Tfec transcription factor EC JBrowse link 4 44,063,533 44,136,815 RGD:1624291
RGD:1600115
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8547793
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1624291
RGD:1600115
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 JBrowse link 5 3,783,247 3,836,485 RGD:10043621
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:11535102
RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1600115
RGD:1624291
G Xylt1 xylosyltransferase 1 JBrowse link 1 186,939,698 187,264,758 RGD:1624291
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon JBrowse link 10 63,884,338 63,921,709 RGD:1624291
RGD:1600115
G Zfand1 zinc finger AN1-type containing 1 JBrowse link 2 93,656,895 93,666,745 RGD:1624291
G Zfp709 zinc finger protein 709 JBrowse link 16 19,632,954 19,643,956 RGD:8553966
heat acclimation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:8662898
mRNA export from nucleus in response to heat stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Polr2d RNA polymerase II subunit D JBrowse link 18 24,570,762 24,577,894 RGD:13792537
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1624291
RGD:1600115
negative regulation of cellular response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:1624291
RGD:1600115
positive regulation of cellular response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ier5 immediate early response 5 JBrowse link 13 72,742,210 72,744,302 RGD:1624291
RGD:1600115
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:1624291
RGD:13792537
G Hsf2 heat shock transcription factor 2 JBrowse link 20 38,935,820 38,963,444 RGD:13792537
G Hsf4 heat shock transcription factor 4 JBrowse link 19 37,225,800 37,232,048 RGD:13792537
G Hsfy2 heat shock transcription factor, Y linked 2 JBrowse link 9 63,289,937 63,291,350 RGD:13792537
regulation of cellular response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chordc1 cysteine and histidine rich domain containing 1 JBrowse link 8 17,421,552 17,445,513 RGD:1624291
RGD:1600115
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:1624291
RGD:1600115
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    response to stimulus 9809
      response to stress 3716
        response to heat 147
          cellular response to heat + 76
          filamentous growth of a population of unicellular organisms in response to heat + 0
          heat acclimation + 6
Path 2
Term Annotations click to browse term
  biological_process 17926
    response to stimulus 9809
      response to abiotic stimulus 1473
        response to temperature stimulus 237
          response to heat 147
            cellular response to heat + 76
            filamentous growth of a population of unicellular organisms in response to heat + 0
            heat acclimation + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.