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ONTOLOGY REPORT - ANNOTATIONS


Term:NAD biosynthetic process
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Accession:GO:0009435 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
Synonyms:exact_synonym: NAD anabolism;   NAD biosynthesis;   NAD formation;   NAD synthesis;   NADH biosynthesis;   NADH biosynthetic process;   nicotinamide adenine dinucleotide biosynthesis;   nicotinamide adenine dinucleotide biosynthetic process;   oxidized NAD biosynthesis;   oxidized NAD biosynthetic process;   oxidized nicotinamide adenine dinucleotide biosynthesis;   oxidized nicotinamide adenine dinucleotide biosynthetic process;   reduced NAD biosynthesis;   reduced NAD biosynthetic process;   reduced nicotinamide adenine dinucleotide biosynthesis;   reduced nicotinamide adenine dinucleotide biosynthetic process
 alt_id: GO:0006736


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NAD biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Aspdh aspartate dehydrogenase domain containing IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:100,471,066...100,473,327
Ensembl chr 1:100,470,722...100,473,459
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase ISO (PMID:28792876) RGD PMID:28792876 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Kynu kynureninase ISS
ISO
GO_REF:0000024
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000024 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Nadsyn1 NAD synthetase 1 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:216,985,710...217,013,743
Ensembl chr 1:216,985,714...217,013,702
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IEA
ISO
GO_REF:0000041
(MGI:3522067|PMID:15381699)
UniProt
RGD
PMID:15381699 GO_REF:0000041, MGI:3522067 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Naprt nicotinate phosphoribosyltransferase IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:8694849, PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 7:116,922,979...116,926,436
Ensembl chr 7:116,922,944...116,926,555
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 IEA
ISO
IBA
GO_REF:0000041
(MGI:3522067|PMID:15381699), (MGI:3654729|PMID:16914673), (MGI:6206974|PMID:27735788)
PMID:21873635
UniProt
RGD
PMID:15381699, PMID:16914673, PMID:27735788, PMID:21873635 GO_REF:0000041, MGI:3522067, MGI:3654729, MGI:6206974, RGD:13792537 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Nmnat2 nicotinamide nucleotide adenylyltransferase 2 IMP
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:22449973, PMID:21873635 GO_REF:0000041, RGD:13782043, RGD:13792537 NCBI chr13:70,379,346...70,559,311
Ensembl chr13:70,379,346...70,559,458
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 IEA
ISO
IBA
GO_REF:0000041
(MGI:3654729|PMID:16914673)
PMID:21873635
UniProt
RGD
PMID:16914673, PMID:21873635 GO_REF:0000041, MGI:3654729, RGD:13792537 NCBI chr 8:106,317,038...106,429,535
Ensembl chr 8:106,317,124...106,429,522
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:234,721,992...234,749,452
Ensembl chr 1:234,721,974...234,749,447
JBrowse link
G Qprt quinolinate phosphoribosyltransferase IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:8694849, PMID:21873635 GO_REF:0000041, RGD:2289495, RGD:13792537 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
NAD salvage term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naprt nicotinate phosphoribosyltransferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:116,922,979...116,926,436
Ensembl chr 7:116,922,944...116,926,555
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      biosynthetic process 6222
        cellular biosynthetic process 6056
          cellular nitrogen compound biosynthetic process 5075
            pyridine-containing compound biosynthetic process 24
              pyridine nucleotide biosynthetic process 19
                nicotinamide nucleotide biosynthetic process 19
                  NAD biosynthetic process 15
                    'de novo' NAD biosynthetic process + 6
                    NAD biosynthesis via nicotinamide riboside salvage pathway 0
                    NAD salvage 1
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        cellular aromatic compound metabolic process 5700
          nucleobase-containing compound metabolic process 5488
            nucleobase-containing small molecule metabolic process 591
              nucleoside phosphate metabolic process 513
                nucleotide metabolic process 506
                  nucleotide biosynthetic process 248
                    pyridine nucleotide biosynthetic process 19
                      nicotinamide nucleotide biosynthetic process 19
                        NAD biosynthetic process 15
                          'de novo' NAD biosynthetic process + 6
                          NAD biosynthesis via nicotinamide riboside salvage pathway 0
                          NAD salvage 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.