ONTOLOGY REPORT - ANNOTATIONS


Term:axis specification
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Accession:GO:0009798 term browser browse the term
Definition:The establishment, maintenance and elaboration of a pattern along a line or around a point.
Synonyms:related_synonym: axis determination


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axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
G Ripply2 ripply transcriptional repressor 2 JBrowse link 8 94,676,579 94,691,125 RGD:1624291
G Wnt6 Wnt family member 6 JBrowse link 9 82,033,543 82,047,172 RGD:1624291
RGD:1600115
anterior/posterior axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:1624291
RGD:1600115
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Cdx1 caudal type homeo box 1 JBrowse link 18 56,337,485 56,355,477 RGD:13792537
G Cdx2 caudal type homeo box 2 JBrowse link 12 9,464,026 9,470,565 RGD:13792537
G Cdx4 caudal type homeo box 4 JBrowse link X 74,165,172 74,173,758 RGD:13792537
G Cer1 cerberus 1, DAN family BMP antagonist JBrowse link 5 101,003,019 101,006,375 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:1624291
RGD:1600115
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
RGD:1600115
G Ldb1 LIM domain binding 1 JBrowse link 1 265,772,729 265,798,442 RGD:1624291
RGD:1600115
G Lefty1 left right determination factor 1 JBrowse link 13 99,212,778 99,217,786 RGD:1624291
RGD:1600115
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
RGD:1600115
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
G Pgap1 post-GPI attachment to proteins 1 JBrowse link 9 61,066,170 61,134,963 RGD:1624291
RGD:1600115
G Rnf2 ring finger protein 2 JBrowse link 13 68,829,714 68,859,920 RGD:1624291
RGD:1600115
G Six2 SIX homeobox 2 JBrowse link 6 8,952,572 8,955,893 RGD:1624291
G Ski SKI proto-oncogene JBrowse link 5 172,556,196 172,623,878 RGD:1624291
G Tbx18 T-box18 JBrowse link 8 95,359,354 95,387,363 RGD:1624291
G Tdgf1 teratocarcinoma-derived growth factor 1 JBrowse link 8 119,215,266 119,220,909 RGD:1624291
G Wls Wnt ligand secretion mediator JBrowse link 2 266,315,036 266,431,220 RGD:1624291
RGD:1600115
G Wnt3 Wnt family member 3 JBrowse link 10 91,830,709 91,874,907 RGD:1624291
RGD:1600115
anterior/posterior axis specification, embryo term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 7 60,128,506 60,210,482 RGD:1624291
RGD:1600115
G Fzd5 frizzled class receptor 5 JBrowse link 9 71,443,784 71,445,541 RGD:1624291
RGD:1600115
G Tbx3 T-box 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
RGD:1600115
G Tcf7l1 transcription factor 7 like 1 JBrowse link 4 100,492,796 100,660,401 RGD:1624291
G Tdgf1 teratocarcinoma-derived growth factor 1 JBrowse link 8 119,215,266 119,220,909 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
dorsal/ventral axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Axin1 axin 1 RGD:1624291
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Mdfi MyoD family inhibitor JBrowse link 9 15,166,118 15,184,469 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Senp2 SUMO specific peptidase 2 JBrowse link 11 82,627,973 82,664,702 RGD:1299408
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Vax2 ventral anterior homeobox 2 JBrowse link 4 115,388,839 115,412,515 RGD:1600115
RGD:1624291
G Wnt3 Wnt family member 3 JBrowse link 10 91,830,709 91,874,907 RGD:1624291
RGD:1600115
embryonic axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:8554075
G Cobl cordon-bleu WH2 repeat protein JBrowse link 14 92,341,949 92,497,169 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Frat1 FRAT regulator of WNT signaling pathway 1 JBrowse link 1 261,071,965 261,075,244 RGD:1624291
G Fzd5 frizzled class receptor 5 JBrowse link 9 71,443,784 71,445,541 RGD:1624291
G Peg12 paternally expressed 12 JBrowse link 1 123,097,861 123,100,464 RGD:1624291
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
G Wnt1 Wnt family member 1 JBrowse link 7 140,464,999 140,469,046 RGD:1624291
RGD:1600115
G Wnt7a Wnt family member 7A JBrowse link 4 122,994,425 123,040,609 RGD:1624291
RGD:1600115
epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
RGD:1600115
establishment of anatomical structure orientation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ttc8 tetratricopeptide repeat domain 8 JBrowse link 6 122,920,308 122,974,525 RGD:1624291
establishment of animal organ orientation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Irx4 iroquois homeobox 4 JBrowse link 1 32,634,774 32,645,151 RGD:1582291
G Wnt8a Wnt family member 8A JBrowse link 18 27,331,236 27,336,829 RGD:1624291
RGD:1600115
growth plate cartilage axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:1624291
RGD:1600115
left/right axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahi1 Abelson helper integration site 1 JBrowse link 1 16,478,127 16,601,769 RGD:1600115
G Arl13b ADP-ribosylation factor like GTPase 13B JBrowse link 7 1,122,567 1,188,209 RGD:1624291
RGD:1600115
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 1 12,823,363 12,825,806 RGD:1624291
RGD:1600115
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1624291
RGD:1600115
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 JBrowse link 13 35,622,472 35,673,449 RGD:1624291
RGD:1600115
G Hspb11 heat shock protein family B (small), member 11 JBrowse link 5 126,856,128 126,882,913 RGD:1624291
RGD:1600115
G Ift172 intraflagellar transport 172 JBrowse link 6 26,390,686 26,485,459 RGD:1624291
G Mns1 meiosis-specific nuclear structural 1 JBrowse link 8 79,054,240 79,075,119 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1624291
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:1624291
RGD:1600115
G Pkd1l1 polycystin 1 like 1, transient receptor potential channel interacting JBrowse link 14 89,047,949 89,193,579 RGD:1624291
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
lung proximal/distal axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:68736
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
neural plate axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2cd3 C2 calcium-dependent domain containing 3 JBrowse link 1 165,382,279 165,480,088 RGD:1624291
RGD:1600115
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
RGD:1600115
P granule organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pld6 phospholipase D family, member 6 JBrowse link 10 46,142,313 46,145,774 RGD:1624291
RGD:1600115
G Tdrd5 tudor domain containing 5 JBrowse link 13 73,872,637 73,922,640 RGD:1600115
RGD:1624291
polarity specification of anterior/posterior axis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Wnt8a Wnt family member 8A JBrowse link 18 27,331,236 27,336,829 RGD:1624291
RGD:1600115
polarity specification of proximal/distal axis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
RGD:1600115
G Wnt8a Wnt family member 8A JBrowse link 18 27,331,236 27,336,829 RGD:1624291
RGD:1600115
primitive streak formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ets2 ETS proto-oncogene 2, transcription factor JBrowse link 11 36,075,709 36,092,495 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
RGD:1600115
G Gdf3 growth differentiation factor 3 JBrowse link 4 155,417,667 155,422,014 RGD:1624291
RGD:1600115
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
RGD:1600115
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
G Otx2 orthodenticle homeobox 2 JBrowse link 15 25,500,037 25,511,619 RGD:1624291
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
proximal/distal axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Six3 SIX homeobox 3 JBrowse link 6 8,886,730 8,891,094 RGD:1624291
regulation of transcription involved in anterior/posterior axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1624291
RGD:1600115
somite rostral/caudal axis specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 JBrowse link 13 35,622,472 35,673,449 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
G Gdf3 growth differentiation factor 3 JBrowse link 4 155,417,667 155,422,014 RGD:1624291
RGD:1600115
G Kdm6a lysine demethylase 6A JBrowse link X 4,805,493 4,945,788 RGD:1624291
RGD:1600115
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
RGD:1600115
G Mesp2 mesoderm posterior bHLH transcription factor 2 JBrowse link 1 141,550,633 141,553,239 RGD:1624291
G Nrarp Notch-regulated ankyrin repeat protein JBrowse link 3 2,396,143 2,398,697 RGD:1624291
RGD:1600115
G Otx2 orthodenticle homeobox 2 JBrowse link 15 25,500,037 25,511,619 RGD:1624291
G Ripply1 ripply transcriptional repressor 1 JBrowse link X 111,099,420 111,114,835 RGD:1624291
G Ripply2 ripply transcriptional repressor 2 JBrowse link 8 94,676,579 94,691,125 RGD:1624291
RGD:1600115
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Tbx6 T-box 6 JBrowse link 1 198,214,797 198,218,706 RGD:1624291
RGD:1600115
G Tmed2 transmembrane p24 trafficking protein 2 JBrowse link 12 37,471,259 37,480,344 RGD:1624291
RGD:1600115
specification of axis polarity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahi1 Abelson helper integration site 1 JBrowse link 1 16,478,127 16,601,769 RGD:1624291
RGD:1600115
G Bcor BCL6 co-repressor JBrowse link X 11,570,155 11,692,022 RGD:1624291
RGD:1600115
thorax and anterior abdomen determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Neurog1 neurogenin 1 JBrowse link 17 9,154,656 9,156,175 RGD:1624291
RGD:1600115
G Tifab TIFA inhibitor JBrowse link 17 9,234,948 9,239,266 RGD:1624291
RGD:1600115
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
RGD:1600115
zygotic determination of anterior/posterior axis, embryo term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nckap1 NCK-associated protein 1 JBrowse link 3 67,725,180 67,804,680 RGD:1624291
G Pcsk6 proprotein convertase subtilisin/kexin type 6 JBrowse link 1 126,749,508 126,947,392 RGD:1624291
RGD:1600115
zygotic specification of dorsal/ventral axis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smad2 SMAD family member 2 JBrowse link 18 72,550,107 72,612,078 RGD:1624291
RGD:1600115
G Smad6 SMAD family member 6 JBrowse link 8 68,897,746 68,967,221 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17895
    multicellular organismal process 8519
      pattern specification process 472
        axis specification 92
          adaxial/abaxial axis specification + 0
          anterior/posterior axis specification + 53
          anterior/posterior axis specification, follicular epithelium 0
          centrolateral axis specification 0
          dorsal/ventral axis specification + 13
          embryonic axis specification + 38
          establishment of anatomical structure orientation + 3
          growth plate cartilage axis specification 1
          left/right axis specification 13
          oocyte axis specification + 2
          proximal/distal axis specification + 4
          radial axis specification 0
          specification of axis polarity + 5
Path 2
Term Annotations click to browse term
  biological_process 17895
    developmental process 6321
      anatomical structure development 5927
        multicellular organism development 5423
          pattern specification process 472
            axis specification 92
              adaxial/abaxial axis specification + 0
              anterior/posterior axis specification + 53
              anterior/posterior axis specification, follicular epithelium 0
              centrolateral axis specification 0
              dorsal/ventral axis specification + 13
              embryonic axis specification + 38
              establishment of anatomical structure orientation + 3
              growth plate cartilage axis specification 1
              left/right axis specification 13
              oocyte axis specification + 2
              proximal/distal axis specification + 4
              radial axis specification 0
              specification of axis polarity + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.